Results 51 to 60 of about 78,364 (310)

ADM1 applications for a hybrid up-flow anaerobic sludge-filter bed reactor performance and for a batch thermophilic anaerobic digestion of thermally pretreated waste activated sludge

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2013
The anaerobic digestion process comprises a whole network of sequential and parallel reactions of biochemical and physicochemical nature. Anaerobic digesters often exhibit significant stability problems that may be avoibed only through appropriate ...
Iván Ramírez
doaj   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min   +6 more
wiley   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao   +11 more
wiley   +1 more source

Anaerobic Digestion

open access: yes, 2018
Anaerobic digestion (AD) is a naturally-occurring biological process in soils, sediments, ruminants, and several other anoxic environments, that cycles carbon and other nutrients, and converts organic matter into a methane-rich gas. As a biotechnology, AD is now well-established for the treatment of the organic fraction of various waste materials ...
Collins, Gavin   +4 more
openaire   +4 more sources

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

open access: yesAdvanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang   +12 more
wiley   +1 more source

Effect of ultrasonic, thermal and ozone pre-treatments on waste activated sludge solubilisation and anaerobic biodegradability [PDF]

open access: yes, 2006
In order to enhance the efficiency of anaerobic digestion, the effects of ultrasounds, ozonation and thermal pre-treatment have been studied on waste activated sludge.
Xin Tian   +7 more
core   +1 more source

Effect of Stillage Pretreatment During a Coupled Scoria-Supported Anaerobic Digestion Followed by Aerobic Degradation

open access: yesAir, Soil and Water Research, 2021
The objective of this study was to evaluate the treatment efficiency of a coupled stillage anaerobic digestion, which was performed in scoria-packed continuous reactors and following aerobic degradation.
Getachew Dagnew Gebreeyessus   +5 more
doaj   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

Energetic and environmental benefits of co-digestion of food waste and cattle slurry: a preliminary assessment [PDF]

open access: yes, 2011
The research evaluated the feasibility of centralised pre-processing and pasteurisation of source-separated domestic food waste followed by transport to farms for anaerobic co-digestion with dairy cattle slurry.
Andrew M. Salter   +8 more
core   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang   +32 more
wiley   +1 more source

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