Results 51 to 60 of about 377,192 (294)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Overcoming sodium toxicity by utilizing grass leaves as co-substrate during the start-up of batch thermophilic anaerobic digestion [PDF]

open access: yes, 2012
Sodium toxicity is a common problem causing inhibition of anaerobic digestion, and digesters treating highly concentrated wastes, such as food and municipal solid waste, and concentrated animal manure, are likely to suffer from partial or complete ...
Suwannoppadol, S.   +2 more
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Life Cycle Assessment and Techno-Economic Assessment of Anaerobic Co-Digestion: A Short Review

open access: yesChemical Engineering Transactions, 2021
Waste-to-energy conversion such as anaerobic digestion has been widely promoted under the subsidies to decouple from fossil fuel dependence system and its inherent two-fold benefits.
Wei En Tan   +5 more
doaj   +1 more source

Comparison of static, in-vessel composting of MSW with thermophilic anaerobic digestion and combinations of the two processes [PDF]

open access: yes, 2009
The biological stabilisation of the organic fraction of municipal solid waste (OFMSW) into a form stable enough for land application can be achieved via aerobic or anaerobic treatments. To investigate the rates of degradation (e.g.
Charles, W.   +2 more
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Effects of rice straw biochar on microbial community structure and metabolic function during anaerobic digestion

open access: yesScientific Reports, 2022
Anaerobic digestion technology mitigates agricultural organic waste pollution, thereby alleviating the energy crisis. Biochar materials increase the utilisation rate of biomass resources and promote the enrichment and growth of microorganisms. Biochar is
Su Wang   +7 more
doaj   +1 more source

Co-digestion of food waste and hydrothermal liquid digestate: Promotion effect of self-generated hydrochars

open access: yesEnvironmental Science and Ecotechnology, 2023
Hydrothermal treatment (HTT) can efficiently valorize the digestate after anaerobic digestion. However, the disposal of the HTT liquid is challenging. This paper proposes a method to recover energy through the anaerobic co-digestion of food waste and HTT
Mingshuai Shao   +6 more
doaj   +1 more source

Rapid start-up of thermophilic anaerobic digestion with the turf fraction of MSW as inoculum [PDF]

open access: yes, 2011
This study aims to determine suitable start-up conditions and inoculum sources for thermophilic anaerobic digestion. Within days of incubation MSW at 55°C, methane was produced at a high rate.
Suwannoppadol, S.   +2 more
core  

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

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