Results 11 to 20 of about 334,223 (370)
Untargeted Metabolomics Reveals Anaerobic Glycolysis as a Novel Target of the Hepatotoxic Antidepressant Nefazodone [PDF]
Journal of Pharmacology and Experimental Therapeutics, 2020 Mitochondrial damage is considered a hallmark of drug-induced liver injury (DILI). However, despite the common molecular etiology, the evolution of the injury is usually unpredictable, with some cases that are mild and reversible upon discontinuation of ...
E.I. Krajnc +6 more
openalex +2 more sources
PLoS ONE, 2023 Candida albicans can cause two major types of infections: superficial infection and systemic candidiasis. C. albicans infects diverse host niches, owing to a wide range of virulence factors and attributes, such as morphological transitions and phenotypic
Ken Okabayashi +7 more
doaj +4 more sources
Transcriptome analysis of anaerobic glycolysis effects on Jurkat T cell proliferation. [PDF]
Cent Eur J ImmunolWang Z +9 more
europepmc +3 more sources
Model evaluation for glycolytic oscillations in yeast biotransformations of xenobiotics [PDF]
Biophysical Chemistry 109, 413-426 (2004), 2004 Anaerobic glycolysis in yeast perturbed by the reduction of xenobiotic ketones is studied numerically in two models which possess the same topology but different levels of complexity. By comparing both models' predictions for concentrations and fluxes as well as steady or oscillatory temporal behavior we answer the question what phenomena require what ...
Beaudoin +48 more
arxiv +5 more sources
Anaerobic Activation of Glycolysis in Tumour Tissue [PDF]
Nature, 1932 ROSENTHAL1 has shown that when the anaerobic conversion of fructose to lactic acid by the Jensen rat sarcoma is studied by Warburg's method, a spontaneous increase in the rate of acid production , which he ascribes to the anaerobic formation of an activator, occurs about forty minutes after the manometric vessels are put into the thermostat at 38° C ...
Frank Dickens, G. D. Greville
openaire +3 more sources
13C nuclear magnetic resonance studies of anaerobic glycolysis in suspensions of yeast cells. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1979 Anaerobic glycolysis in Saccharomyces cerevisiae has been studied by 13C NMR at 90.5 MHz. [1-13c]Glucose and [6-13C]glucose were fed to suspensions of yeast cells.
Jan A. den Hollander +3 more
openalex +2 more sources
The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis [PDF]
Genes & Development, 2007 Mammalian cells are believed to have a cell-intrinsic ability to increase glucose metabolism in response to hypoxia. Here we show that the ability of hematopoietic cells to up-regulate anaerobic glycolysis in response to hypoxia is dependent on receptor ...
Julian J. Lum +7 more
openalex +2 more sources
In vitro inhibition of anaerobic glycolysis by phenothiazine ataractic drugs [PDF]
Experientia, 1960 Im Gegensatz zu Feststellungen anderer Forscher hemmten Chlorpromazin und zwei strukturell verwandte ataraktisch wirkende Phenothiazinderivate die anaerobe Glykolyse von homogenisiertem Rattenhirn. Der Nachweis dieser Hemmung bedarf einer langeren Inkubation, was auf die Mitwirkung eines zeitbedingten Vorgangs, wie metabolische Umwandlung der ...
James A. Buzard
openaire +3 more sources
Rôle of glutathione in anaerobic tissue glycolysis [PDF]
Biochemical Journal, 1935 A. Geiger
openaire +4 more sources
American Journal of Physiology. Heart and Circulatory Physiology, 2008 The role of anaerobic glycolysis and oxidative substrate selection on contractile function and mechanical efficiency during moderate severity myocardial ischemia is unclear.
Lufang Zhou +4 more
openalex +3 more sources