Results 11 to 20 of about 71,019 (261)
Cardiosphere-derived cells demonstrate metabolic flexibility that Is influenced by adhesion status [PDF]
, 2017 Adult stem cells demonstrate metabolic flexibility that is regulated by cell adhesion status. The authors demonstrate that adherent cells primarily utilize glycolysis, whereas suspended cells rely on oxidative phosphorylation for their ATP needs.
Abraham, M. Roselle +13 more
core +2 more sources
iScience, 2022 Summary: In this study, we explore the role of nuclear survivin in maintaining the effector phenotype of IFNγ-producing T cells acting through the transcriptional control of glucose utilization.
Malin C. Erlandsson +11 more
doaj +1 more source
Synaptic modifications transform neural networks to function without oxygen
BMC Biology, 2023 Background Neural circuit function is highly sensitive to energetic limitations. Much like mammals, brain activity in American bullfrogs quickly fails in hypoxia.
Lara Amaral-Silva, Joseph M. Santin
doaj +1 more source
The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]
, 1993 Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Grafe, Peter +2 more
core +1 more source
Frontiers in Plant Science, 2023 Viruses often establish their own infection by altering host metabolism. How viruses co-opt plant metabolism to support their successful infection remains an open question.
Tong Jiang +12 more
doaj +1 more source
Frontiers in Integrative Neuroscience, 2017 The 1988 observation by Fox et al. (1988) that brief intense brain activation increases glycolysis (pyruvate formation from glucose) much more than oxidative metabolism has been abundantly confirmed.
Leif Hertz, Ye Chen
doaj +1 more source
Cells, 2022 Fanconi Anaemia (FA) is a rare recessive genetic disorder characterized by a defective DNA repair mechanism. Although aplastic anaemia is the principal clinical sign in FA, patients develop a head and neck squamous cell carcinoma (HNSCC) with a frequency
Nadia Bertola +3 more
doaj +1 more source
A role for glyceraldehyde-3-phosphate dehydrogenase in the development of thermotolerance in Xenopus laevis embryos [PDF]
, 1988 During heat shock, Xenopus laevis embryos exhibit an increase in the rate of accumulation of lactate and a loss of ATP relative to non-heat- shocked control embryos.
Browder, Leon W., Nickells, Robert W.
core +2 more sources
Synthesis and application of (18F) fluorodeoxyglucose in oncology diagnosis
Journal of Education, Health and Sport, 2017 [18F] Fluorodeoxyglucose ([18F] FDG) is the most commonly used radiopharmaceutical in clinical positron emission tomography (PET) in oncology. Cancer cells create their own specific microenvironment to survive and grow.
Mateusz Wędrowski +6 more
doaj +3 more sources
Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells. [PDF]
, 2017 Glioblastoma (GBM) stem cells (GSCs) reside in both hypoxic and vascular microenvironments within tumors. The molecular mechanisms that allow GSCs to occupy such contrasting niches are not understood.
Barcellos-Hoff, Mary Helen +20 more
core +5 more sources