T Cell Exhaustion in Hepatocellular Carcinoma: A Substantial Barrier in Immunotherapy
ABSTRACT Hepatocellular carcinoma (HCC), accounting for over 90% of primary liver cancers, remains a major global challenge for healthcare professionals. While immunotherapy has transformed the landscape of cancer treatment, its success is often limited by immune resistance, particularly through T cell exhaustion which remains a major barrier to ...
Kosar Nouri +7 more
wiley +1 more source
m6A reader IGF2BP2 mediates paclitaxel resistance in esophageal squamous cell carcinoma via FOXM1 mRNA stabilization. [PDF]
Ren S, Wu J, Zhang L, Guan G, Jiang W.
europepmc +1 more source
Cardiac activity cessation during slaughtering combinations in farmed European seabass
Abstract Ensuring fish welfare during stunning and slaughter is essential, as these procedures represent critical points in the production cycle that can significantly impact animal welfare. Cardiac activity serves as a key physiological indicator to assess stress responses and welfare in fish.
E. Hoyo‐Alvarez +4 more
wiley +1 more source
Research Progress on the Regulation of Glycolysis in Gastric Cancer: Key Genes and Enzymes. [PDF]
Chen Z, Li J, Ju H, Yang M, Zhao T.
europepmc +1 more source
Resistance of mature and elderly bodybuilders to anaerobic energy supply load. [PDF]
Chernozub A +8 more
europepmc +1 more source
Carbonic Anhydrase between Aerobic and Anaerobic Glycolysis [PDF]
openaire +1 more source
Metabolic flux analysis revealed key roles of ArcB in ADI pathway and IlvC in BCAA biosynthesis during <i>Streptococcus suis</i> anaerobic growth and infection. [PDF]
Tang H +12 more
europepmc +1 more source
Molecular and Physiological Mechanisms Underlying Submerged Germination in Rice. [PDF]
Jia S, Zhou Q, Yuan S, Wang Y, Zhang Z.
europepmc +1 more source
Genome-resolved insights into the bacterial phylum WOR-3: hydrogenotrophic metabolism and unique carbon fixation via archaeal form III RuBisCO. [PDF]
Zeng J +8 more
europepmc +1 more source

