Results 191 to 200 of about 341,458 (322)

Yak (Bos grunniens) Meat Peptides: Effects on Immunity, Hypoxia Tolerance, and Antioxidant Capacity in Hypotonic Hypoxia Mice

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
Yak meat peptides can increase immune cell content, oxygen transport capacity, and antioxidant enzyme activities in hypotonic hypoxic mice. Meanwhile, they can reduce oxidative stress, thus enhancing the immunity, antioxidant capacity, and hypoxia tolerance of these mice. They also upregulate hypoxia‐related genes HIF and EPO.
Gaiming Zhao, Ying Zhang, Ke Wang, Long Xu, Mancai Yin, Xiangying Kong, Chaozhi Zhu   +6 more
wiley   +1 more source

Exploring Astragaloside IV in Ischemic Heart Disease: A Comprehensive Systematic Review and Meta‐Analysis of Preclinical Cardiotoxicity Models

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 7, July 2025.
This systematic review and meta‐analysis evaluated the therapeutic efficacy of Astragaloside IV in ischemic heart disease, encompassing 18 preclinical studies. The findings demonstrated that As‐IV significantly reduced myocardial infarction size and apoptosis while improving cardiac function and angiogenesis through various mechanisms, along with ...
Alosh Greeny, Gollapalle Lakshminarayanashastry Viswanatha, Rekha Raghuveer Shenoy, Shylaja Hanumanthappa, Dinesh Kumar Chellappan, Jagnoor Singh Sandhu, Saumya Khanna, Nandakumar Krishnadas   +7 more
wiley   +1 more source

Examining mixotrophic fermentation in fed‐batch mode for C1‐gas valorization

Journal of Chemical Technology &Biotechnology, Volume 100, Issue 7, Page 1453-1462, July 2025.
Abstract BACKGROUND C1‐gases like CO and CO2, significant contributors to climate change, offer the potential for sustainable bioconversion into valuable products. The study explored mixotrophic fermentation using C1‐gases in fed‐batch mode to improve the production of target compounds, focusing on Clostridium aceticum and Clostridium carboxidivorans ...
Marina Fernández‐Delgado, Pedro Enrique Plaza, M Teresa García‐Cubero, Susana Lucas, Mónica Coca, Juan Carlos López‐Linares   +5 more
wiley   +1 more source

Glutamine Metabolism: Molecular Regulation, Biological Functions, and Diseases

MedComm, Volume 6, Issue 7, July 2025.
Tumor cells adapt to nutrient‐poor environments by altering metabolism to acquire essential nutrients. They convert glutamine into glutamate and α‐ketoglutarate, supporting mTOR activation and sugar biosynthesis. Disruption of mTORC1 signaling is linked to disease, while glutamine and leucine activation promotes cell growth and inhibits autophagy ...
Mudasir A. Kumar, Sana Khurshid Baba, Inamu Rashid Khan, Mohd Shahnawaz Khan, Fohad Mabood Husain, Saheem Ahmad, Mohammad Haris, Mayank Singh, Ammira S. Al‐Shabeeb Akil, Muzafar A. Macha, Ajaz A. Bhat   +10 more
wiley   +1 more source

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat

Science, 2017
T. Park, J. Reznick, Bethany L. Peterson, Gregory Blass, Damir Omerbašić, N. Bennett, P. H. J. L. Kuich, Christin Zasada, Brigitte M. Browe, Wiebke Hamann, Daniel T. Applegate, M. Radke, Tetiana Kosten, H. Lutermann, Victoria Gavaghan, Ole Eigenbrod, V. Bégay, Vince G Amoroso, V. Govind, R. Minshall, E. Smith, J. Larson, M. Gotthardt, S. Kempa, G. Lewin, G. Lewin   +25 more
semanticscholar   +1 more source

Lactate Metabolism and Lactylation Modification: New Opportunities and Challenges in Cardiovascular Disease

MedComm, Volume 6, Issue 7, July 2025.
Lactate, beyond a metabolic byproduct, regulates immunity and inflammation, linked to cardiovascular diseases (CVD) via metabolic reprogramming. Lactylation, a lactate‐driven epigenetic mark, modulates gene expression in fibrosis, lipid disorders, and CVD progression.
Mengyang Song, Bin Liu, Haiou Wang, Wei Sun   +3 more
wiley   +1 more source

Low oxygen tension during IVM improves bovine oocyte competence and enhances anaerobic glycolysis.

Reproductive Biomedicine Online, 2010
P. Bermejo-Álvarez, Patrick Lonergan, D. Rizos, Alfonso Gutiérrez-Adán   +3 more
semanticscholar   +1 more source

Dad's legacy: Epigenetic reprogramming and paternal inflammatory memory in offspring health

Journal of Internal Medicine, Volume 298, Issue 1, Page 16-30, July 2025.
Abstract Over the past decade, numerous reports have highlighted intergenerational and even transgenerational epigenetic effects resulting from parental exposure to diets, toxins, and stress. In many cases, these parentally induced phenotypes do not seem to confer an obvious benefit, making it challenging to understand the evolutionary drivers behind ...
Shamila D. Alipoor, Parisa Norouzitallab, Anita Öst, Maria Lerm   +3 more
wiley   +1 more source

Speed Endurance Training to Improve Performance

Scandinavian Journal of Medicine &Science in Sports, Volume 35, Issue 7, July 2025.
ABSTRACT In many sports, the physical dimension plays a crucial role in determining athletic performance. This review provides insights into the effectiveness of speed endurance training (SET), that is, exercise training performed at intensities higher than that eliciting maximum oxygen uptake (V̇O2‐max), on performance across different sports and ...
Jens Bangsbo, Julie Kissow, Morten Hostrup   +2 more
wiley   +1 more source

Bufalin-Loaded Multifunctional Photothermal Nanoparticles Inhibit the Anaerobic Glycolysis by Targeting SRC-3/HIF-1α Pathway for Improved Mild Photothermal Therapy in CRC. [PDF]

Int J Nanomedicine
Shang J, Xia Q, Sun Y, Wang H, Chen J, Li Y, Gao F, Yin P, Yuan Z.   +8 more
europepmc   +1 more source