Results 171 to 180 of about 41,612 (257)

V̇O2max$\dot V_{\rm{O_{2max}}}$‐based all‐out aerobic exercise attenuates hexosamine biosynthetic pathway activity: Metabolomic insights in mice model

open access: yesExperimental Physiology, Volume 111, Issue 7, Page 3253-3266, 1 July 2026.
Abstract Aerobic exercise enhances physiological performance by activating metabolic systems, including glucose oxidation and fat metabolism. Cellular glucose predominantly flows through glycolysis (95–98%), whereas a smaller fraction (2–5%) enters the hexosamine biosynthetic pathway (HBP), generating UDP‐N‐acetylglucosamine.
Gyumin Kang   +3 more
wiley   +1 more source

Skeletal muscle‐specific myostatin overexpression promotes muscle oxidative capacity and fatigue resistance in transgenic mice

open access: yesExperimental Physiology, Volume 111, Issue 7, Page 3357-3380, 1 July 2026.
Abstract In addition to controlling muscle mass, myostatin may support oxidative metabolism and endurance. Loss of function through gene knockout or post‐natal blockade generally lowers muscle oxidative capacity and increases fatigability. These observations imply that myostatin activation could promote a more oxidative and less fatigable muscle ...
Andy V. Khamoui   +6 more
wiley   +1 more source

Acute hypoxia impairs uphill running performance and alters metabolic responses in adult trained trail runners: A pilot study

open access: yesPhysiological Reports, Volume 14, Issue 13, July 2026.
Acute normobaric hypoxia (~2,500 m) reduced uphill 12‐min time‐trial performance (distance, speed, and power) by ~15% while increasing metabolic strain (higher RER and blood lactate, lower V̇O₂), with comparable responses in trained male and female trail runners.
Diego Jaén‐Carrillo   +3 more
wiley   +1 more source

The effects of breath holding during high‐intensity land‐based ergometry in swimmers

open access: yesPhysiological Reports, Volume 14, Issue 13, July 2026.
Abstract The aim of this study was to compare cardiorespiratory responses during high‐intensity land‐based exercise between free‐breathing and breath‐holding conditions in swimmers. Twenty varsity swimmers (20 ± 2 years, 10 females) performed 20 s bouts of simultaneous arm and leg ergometry exercise at high intensity (total power output = 606 ± 76 W ...
Jeremy Walsh   +6 more
wiley   +1 more source

Correction: Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis.

open access: yesElife
Watanuki S   +27 more
europepmc   +1 more source

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