Results 161 to 170 of about 41,612 (257)

Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis. [PDF]

Elife
Watanuki S, Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Fujita S, Morikawa T, Koide S, Oshima M, Nishiyama A, Murakami K, Haraguchi M, Tamaki S, Yamamoto T, Yabushita T, Tanaka Y, Nagamatsu G, Honda H, Okamoto S, Goda N, Tamura T, Nakamura-Ishizu A, Suematsu M, Iwama A, Suda T, Takubo K.   +27 more
europepmc   +1 more source

In Situ pH Determination Using 1H‐MRS Acetate Chemical Shift for Noninvasive Postmortem Examinations

NMR in Biomedicine, Volume 39, Issue 7, July 2026.
The chemical‐shift difference between acetate and myo‐inositol measured by MRS enables estimation of pH in the acidic range. Noninvasive pH assessment in forensic investigations is demonstrated in 58 cases and validated by measurements in extracted tissue.
Sabina Frese, Dominic Gascho, Michael J. Thali, Sebastian Kozerke, Niklaus Zoelch   +4 more
wiley   +1 more source

Bufalin-Loaded Multifunctional Photothermal Nanoparticles Inhibit the Anaerobic Glycolysis by Targeting SRC-3/HIF-1α Pathway for Improved Mild Photothermal Therapy in CRC. [PDF]

Int J Nanomedicine
Shang J, Xia Q, Sun Y, Wang H, Chen J, Li Y, Gao F, Yin P, Yuan Z.   +8 more
europepmc   +1 more source

ANAEROBIC GLYCOLYSIS BY ENZYME PREPARATIONS OF BRUCELLA SUIS

Journal of Biological Chemistry, 1952
W G, ROESSLER, T H, SANDERS, J, DULBERG, C R, BREWER   +3 more
openaire   +2 more sources

Sustained Hypoxia‐Inducible Factor 1‐Alpha Accumulation Disrupts the Articular Niche to Promote Osteoarthritis Pathogenesis

Aging Cell, Volume 25, Issue 7, July 2026.
Sustained HIF‐1α accumulation is not a compensatory shield, but a potent pathogenic driver of osteoarthritis. Continuous HIF‐1α signaling physically eradicates the avascular cartilage niche and primes the synovium for inflammation, establishing HIF‐1α as a critical target for disease‐modifying therapies.
Weiyuan Gong, Chu Tao, Xingyun Wang, Rongdong Liao, Jianglong Li, Xiongtian Guo, Minghao Qu, Jianmei Huang, Mingjue Chen, Fuxin Wei, Peng Wang, Lijun Lin, Di Chen, Qing Yao, Chunyi Wen, Guozhi Xiao   +15 more
wiley   +1 more source

Cerebral metabolism in anoxia and the effects of some neurotropic drugs

, 1971
The effects of tetrodotoxin (TTX) and other neurotropic drugs on anaerobic glycolysis, and on transport processes, of incubated cerebral cortex slices have been studied in an effort to understand more fully cerebral metabolic processes during anoxia, and
Shankar, Raj
core  

Levothyroxine Treatment During Pregnancy: A Metabolomics Study

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Levothyroxine is one of the most prescribed drugs during pregnancy. Our aim was to determine levothyroxine treatment‐associated changes in the metabolite profiles and link these to the health of the newborn. Metabolite profiles of 118 levothyroxine‐treated and 118 healthy control pregnancies were determined with nuclear magnetic resonance ...
Olli Kärkkäinen, Heidi Sahlman, Leea Keski‐Nisula, Jaana Rysä   +3 more
wiley   +1 more source

Mechanisms and Clinical Manifestations of Age‐Related Impairment in Wound Healing

International Wound Journal, Volume 23, Issue 7, July 2026.
ABSTRACT Chronic wounds account for a considerable burden on the overall US healthcare system, affecting an estimated 10.2 million people and costing as much as $148 billion dollars in 2022 alone. Elderly patients suffer disproportionately, as nearly 85% of the chronic wound population is over the age of 65 years old.
Daniel A. Rabin, Tiffany Kim, Julia K. Kaniuk, Marlynn P. Lopez, Spencer Green, Aneeq S. Chaudhry, Katherine Kozlowski, Diana Griffin, Tarifa H. Adam, Thomas A. Mustoe, Robert D. Galiano   +10 more
wiley   +1 more source

PGK1 Drives Glial Glycolytic Reprogramming to Mediate Isoflurane‐Induced Cognitive Impairment in Aged Mice

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Isoflurane‐induced neuroinflammation triggers cognitive impairment in aged mice, but its underlying mechanism remains unclear. This study investigated the molecular mechanism by which isoflurane promotes glycolytic reprogramming to cause cognitive dysfunction in aged mice and identified potential therapeutic targets.
Zhuo Ren, Huaying Hu, Jiahao Guo, Yajun Liu, Chenyang Qiu, Kai Yuan, Yujie Ma, Shuntao Jiao, Ruiyun Guo, Dengfa Zhao, Dongliang Zhang, Yang Zeng, Jun Ma, Mianwang He   +13 more
wiley   +1 more source

Balancing Aerobic and Anaerobic Metabolism, and Its Effect on Recovery Time in Freely‐Diving Steller Sea Lions (Eumetopias jubatus)

Marine Mammal Science, Volume 42, Issue 3, July 2026.
ABSTRACT As breath‐hold divers, marine mammals must coordinate their use of both aerobic and anaerobic metabolism to maximize their time at depth. One indication of the relative reliance between these two energy‐producing systems is the aerobic dive limit (ADL), defined as the dive duration where post‐dive blood lactate concentrations surpass resting ...
Aaron S. Purdy, David A. S. Rosen
wiley   +1 more source