Results 141 to 150 of about 261,537 (268)

First-stage and single-stage continuously stirred tank anaerobic digestion of synthetic complex wastewater and piggery wastewater (with emphasis on thermophilic temperature) [PDF]

open access: yes, 2010
Single-stage continuously stirred tank reactor (CSTR) is commonly used in the anaerobic treatment of animal manure slurry, municipal sewage sludge and concentrated wastewaters containing a high proportion of biodegradable particulate organic materials at
Ho, Lily S.H.
core  

Maternal protein restriction programs the ageing kidney: Proteomic signatures of early‐life origin renal and metabolic dysfunction

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires   +15 more
wiley   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

open access: yesComputational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman   +2 more
wiley   +1 more source

Antibiofilm Activity of a Thermoformable Material Loaded With Essential Oil Solution

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 5, October 2026.
ABSTRACT Background Interest in antimicrobial surfaces for dental devices, such as aligners and brackets, is growing. These surfaces are designed to retard biofilm formation. One approach is to load essential oils (EOs) into the material. The focus of this study was the antibacterial, anti‐biofilm, and anti‐inflammatory activities of an EO solution ...
Alexandra Stähli   +4 more
wiley   +1 more source

Anaerobic digestion in sustainable biomass chains [PDF]

open access: yes, 2009
This thesis evaluates the potential contribution of anaerobic digestion (AD) to the sustainability of biomass chains. Results provide insights in the technological potential to recover energy and valuable by-products from energy crops and residues, and ...
Pabon Pereira, C.P.
core  

Securidaca inappendiculata Extract Mitigates Joint Damage in Collagen‐Induced Arthritis Rats Through Modulation of the SIRT1/HIF‐1α/Glycolysis Pathway

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Securidaca inappendiculata (SI) Hassk. is a traditional Chinese herbal medicine commonly used in Southern China for the treatment of rheumatoid arthritis (RA). However, its exact mechanism of action remains unclear. In this study, we evaluated the therapeutic effects of the SI‐derived compound 1,7‐dihydroxy‐3,4‐dimethoxyxanthone (XAN) in a ...
Yuyan Zhou   +6 more
wiley   +1 more source

An Acidic Tubulointerstitial Microenvironment Delays Cell‐Cycle Progression in Proximal Tubule Cells and Fibroblasts and Synergizes With Lactate to Drive Phenotypic Alterations

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Background Chronic kidney disease (CKD) is characterized by progressive tubulointerstitial inflammation and fibrosis, particularly affecting the proximal tubule. Both proximal tubular epithelial cells and interstitial fibroblasts contribute to CKD progression through cell‐cycle arrest and phenotypic transitions.
Marie‐Christin Schulz   +8 more
wiley   +1 more source

The Crosstalk Between Diabetes and Alzheimer's Disease: A Molecular Perspective

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
Increasing evidence indicates an association between type 2 diabetes mellitus and Alzheimer’s disease, contributing to the proposed concept of AD as “type 3 diabetes.” Shared biological features such as impaired insulin signaling, chronic inflammation, mitochondrial dysfunction, and oxidative stress have been observed in both T2DM and AD.
Deniz Catakli   +3 more
wiley   +1 more source

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