Results 121 to 130 of about 314,893 (262)

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Biochemical Difference of Tissues of Gastric Cancer between Lesser and Greater Curvatures Part 1 On Tissue Respiration, Aerobic and Anaerobic Glycolysis [PDF]

, 1959
Cases of gastric cancer were classified into two types, i.e. the localized and infiltrating ones. Specimens were taken from the cancer and the neighbouring part of it on sides of the greater and the lesser curvatures, and tissue respiration, aerobic and ...
Asahina, Masaru
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Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Immunometabolic effects of lactate on humoral immunity in healthy individuals of different ages

Nature Communications
Aging is characterized by chronic systemic inflammation and metabolic changes. We compare the metabolic status of B cells from young and elderly donors and found that aging is associated with higher oxygen consumption rates, and especially higher ...
Maria Romero, Kate Miller, Andrew Gelsomini, Denisse Garcia, Kevin Li, Dhananjay Suresh, Daniela Frasca   +6 more
doaj   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Mapping the omics landscape for peri‐implant diseases: A scoping review

Periodontology 2000, EarlyView.
Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng, Ioannis Fragkioudakis, Jeniffer Perussolo, John Rong Hao Tay, Elena Calciolari, Nikos Donos   +5 more
wiley   +1 more source

Enhancers regulate anaerobic glycolysis in old cardiomyocytes

, 2019
Heart failure is a typical age-associated pathology with high rates of mortality and morbidity. Age-related cardiac malfunctioning is multifactorial and cardiac remodelling contributes to this.
Pierluigi Carullo, Nadia Corrado, Papait Roberto, Gianluigi Condorelli, Christina Pagiatakis, Simone Serio   +5 more
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Metabolic reprogramming of the immune response in periodontitis

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon, Melissa Grant, Iain Chapple, Joao Paulo Steffens   +3 more
wiley   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Factors affecting the anaerobic glycolysis of brain tissue and the effects of sodium and potassium on brain metabolism.

, 1956
The experiments to be presented consist of an attempt to extend the observations of Dickens and Greville on the effects of anoxia and lack of substrate on the subsequent carbohydrate metabolism of brain tissue.
Rosenfeld, Michael. W.
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