Cell Proliferation, EarlyView.The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou +8 more
wiley +1 more source
Lactate and Lactylation: What We Know and What We Expect in Tumour Progression
Cell Proliferation, EarlyView.Lactate and lactylation in cancer cells have been shown to accelerate tumour development in various ways, including stemness generation, metabolic dysregulation, cell death, chemotherapy resistance, and cell cycle disorder. In addition, lactate and lactylation promote angiogenesis and create an immunosuppressive microenvironment, which promotes tumour ...
Qi Zhang, Zhenzhen Han, Youjia Duan
wiley +1 more source
Pasteur effect in leukocyte energy metabolism of patients with mild, moderate, and severe COVID-19
Türk Biyokimya DergisiThe Pasteur effect in cellular energy metabolism is defined as the switch to anaerobic glycolysis due to alterations in ambient oxygen concentration or inhibition of the electron transport chain (ETC) and oxidative phosphorylation.
Ortatatli Mesut +5 more
doaj +1 more source
Common pathways and outliers in glucose catabolism across Trypanosomatidae
The FEBS Journal, EarlyView.Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes +5 more
wiley +1 more source
SNHG17 alters anaerobic glycolysis by resetting phosphorylation modification of PGK1 to foster pro-tumor macrophage formation in pancreatic ductal adenocarcinoma. [PDF]
J Exp Clin Cancer Res, 2023 Lin J +11 more
europepmc +1 more source
Studies on the Oxygen Consumption and Glycolysis of Bone Marrow Part 2. A Study on the Glycolysis of the Sternal Bone Marrow in Various Leukemias [PDF]
, 1959 With the sternal bone marrow obtained from various leukemias definitely diagnosed by their bone-marrow tissue culture the author measured the glycolysis in the sternal bone marrow and obtained the following results. 1.
Sanada, Hiroshi
core
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis. [PDF]
Cell Death Dis, 2022 Lu C +9 more
europepmc +1 more source
Four Haylages, One Metabonome: Defining Diet Driven Metabolic Shifts in Ponies
Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT Haylage is widely fed to all categories of stabled horses across Europe and New Zealand. Haylage can vary from high energy nutrient dense forage to low energy highly fibrous fodder, yet little is known about the impact different haylages have on metabolism in horses.
Meriel Moore‐Colyer +2 more
wiley +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
Journal of Periodontal Research, EarlyView.A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger +5 more
wiley +1 more source
Eccentric Cycling Training Improves Erythrocyte Antioxidant and Oxygen Releasing Capacity Associated with Enhanced Anaerobic Glycolysis and Intracellular Acidosis. [PDF]
Antioxidants (Basel), 2021 Huang YC +5 more
europepmc +1 more source