Results 211 to 220 of about 345,476 (333)
Glucose Metabolic Reprogramming in Colorectal Cancer: From Mechanisms to Targeted Therapy Approaches
Cancer Medicine, Volume 14, Issue 17, September 2025.ABSTRACT Background Colorectal cancer (CRC) is one of the most common malignant tumors, and its morbidity ranks third among all cancers, with a trend toward younger patients. Metabolic reprogramming, a unique metabolic mode in tumor cells, is closely related to the occurrence and development of CRC. Numerous studies have confirmed that many genetic and
Runkai Zhou +4 more
wiley +1 more source
Journal of Cell Communication and Signaling, Volume 19, Issue 3, September 2025.The top row shows key drivers‐KRAS, c‐Myc and HIF‐1a‐alongside gut and tumor microbiota, all converging on glutamine metabolism in PDAC. At the center, glutamine handling is depicted as the linchpin of tumor growth, biosynthesis and immune modulation. The green panel lists major intervention strategies: DON‐loaded nanoparticles, prodrugs (DRP‐104/JHU ...
Min Su +4 more
wiley +1 more source
Clinical and Translational Medicine, Volume 15, Issue 9, September 2025.Unique metabolic signatures are associated with both response and resistance to cancer immunotherapy. These signatures can be used to predict response to treatment and in the future, metabolites could potentially be used to enhance specific types of immune response associated with favourable immunological outcomes. Abstract Checkpoint inhibitor therapy
Agnieszka Beata Malczewski +3 more
wiley +1 more source
Endocrinology, Diabetes &Metabolism, Volume 8, Issue 5, September 2025.Trifolium pratense‐derived exosomes improved the biochemical factors and pancreas regeneration in diabetic rats. ABSTRACT Introduction Plant‐derived exosomes (PDEs) are promising nanotherapeutics for improving chronic diseases, such as diabetes mellitus.
Amir Hossein Khazaei +4 more
wiley +1 more source
Food Frontiers, Volume 6, Issue 5, Page 2470-2484, September 2025.ABSTRACT Germinated brown rice is increasingly recognized for its physiological benefits. However, the effects of germination on its processing properties, as well as on the composition of its volatile and non‐volatile metabolites, have not been systematically elucidated.
Xiuqi Wang +7 more
wiley +1 more source