Results 51 to 60 of about 417,945 (311)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Anaesthesia Fluid Detection in 3D Contrast Enhanced Ultrasound Image [PDF]

open access: yes, 2011
Ultrasound medical image has disadvantage on displaying anaesthesia fluid due to its low intensity. Using contrast agent to enhance brightness of fluid area makes it possible to extract fluid area from acquired 3D image. This paper proposes
Alkaff, Dalily
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Maximising ophthalmic theatre time : part 1 [PDF]

open access: yes, 2011
Part 2 of the article can be found through this link : https://www.um.edu.mt/library/oar//handle/123456789/12822Aim: To establish whether the available ophthalmic theatre time is being used efficiently and to find ways how to improve our surgical ...
Agius, Maria   +2 more
core   +4 more sources

Ultrasound-guided caudal anaesthesia combined with epidural anaesthesia for caesarean section: a randomized controlled clinical trial

open access: yesBMC Pregnancy and Childbirth
Background Although epidural anaesthesia and spinal anaesthesia are currently the general choices for patients undergoing caesarean section, these two neuraxial anaesthesia methods still have drawbacks.
Fangjun Wang   +6 more
doaj   +1 more source

Low flow practice for laparoscopic colorectal surgery in pediatric patients

open access: yesBali Journal of Anesthesiology, 2018
Low flow anaesthesia and laparoscopic techniques in pediatric patients are two of many developments in the modern medical field. Both techniques were established to support environmentally friendly, safe, and comfortable anaesthesia practices for ...
Tjokorda Gde Agung Senapathi   +4 more
doaj   +1 more source

Data Collection for the Fourth Multicentre Confidential Enquiry into Perioperative Equine Fatalities (CEPEF4) Study: New Technology and Preliminary Results

open access: yesAnimals, 2021
It is almost 20 years since the largest observational, multicentre study evaluating the risks of mortality associated with general anaesthesia in horses. We proposed an internet-based method to collect data (cleaned and analysed with R) in a multicentre,
Miguel Gozalo-Marcilla   +4 more
doaj   +1 more source

Chaos-modified detrended moving average methodology for monitoring the depth of anaesthesia [PDF]

open access: yes, 2013
This paper proposes a new method to monitor the depth of anaesthesia (DoA) based on the EEG signal. This approach firstly uses discrete wavelet transform (DWT) to to remove the spikes and the low frequency noise from raw EEG signals. After de-noising the
Li, Yan, Nguyen-Ky, T., Wen, Peng
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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