Results 71 to 80 of about 417,945 (311)

Technical aspects of an impact acceleration traumatic brain injury rat model with potential suitability for both microdialysis and PtiO2 monitoring

, 2007
This report describes technical adaptations of a traumatic brain injury (TBI) model-largely inspired by Marmarou-in order to monitor microdialysis data and PtiO2 (brain tissue oxygen) before, during and after injury. We particularly focalize on our model
Bruno Palmier, Bullock, Emilie Carré, Emmanuel Cantais, Foda, Gentleman, Jean-Jacques Risso, Jean-Pierre Terrier, Kawaguchi, Marmarou, Michel Lonjon, Olivier Darbin, Paxinos, Piper, Povlishock, Schallert, Warner   +16 more
core   +1 more source

Lumbar puncture for the generalist [PDF]

, 2004
The safe and successful performance of a lumbar puncture demands a working and yet specific knowledge as well as competency in performance. This review aims to aid understanding of the knowledge framework, the pitfalls and complications of lumbar ...
Abrahams, Peter H., Boon, J. M., Meiring, J. H., Welch, T.   +3 more
core   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Management of paediatric procedure-related cancer pain

, 1999
Paediatric malignancy is not always painful in its own right; however, young patients with cancer undergo numerous painful procedures for diagnosis, therapy and supportive care, including lumbar puncture, bone marrow aspiration and biopsy.
Liossi, C.
core   +1 more source

Clinical judgement, expertise and skilled coping [PDF]

, 2010
Medicine involves specific practical expertise as well as more general context-independent medical knowledge. This raises the question, what is the nature of the expertise involved?
Aristotle, Carruthers, Dreyfus, Dreyfus, Dreyfus, Dreyfus, Kant, McDowell, McDowell, McDowell, Pope, Ratcliffe, Rouse, Sellars, Smith, Thornton, Thornton, Travis   +17 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Effect of epidural administration of lidocaine, fentanyl and their combination on the minimum alveolar concentration of halothane in dogs

Veterinární Medicína, 2004
The efficacy of lidocaine, fentanyl, combination of both (2 mg/kg of lidocaine, along with fentanyl in the dose of 0.005 mg/kg) and saline (as a control) administered epidurally to 40 healthy dogs was under investigation, regarding their influence on ...
P. Rauser, L. Lexmaulova, M. Vlasin, T. Fichtel, J. Lorenzova   +4 more
doaj   +1 more source

Gamma radiation-induced impairment of hippocampal neurogenesis, comparison of single and fractionated dose regimens Deterioro de la neurogénesis en el hipocampo inducida por radiación gamma, comparación de los regímenes de dosis única y fraccionada [PDF]

, 2012
Radiation therapy of the brain is associated with many consequences, including cognitive disorders. Pathogenesis of radiation induced cognitive disorder is not clear, but reduction of neurogenesis in hippocampus may be an underlying reason. 24 adult male
Azami, N.S., Jahanshahi, M., Khoshbin khoshnazar, A.R.   +2 more
core  

The effects on arterial haemoglobin oxygen saturation and on shunt of increasing cardiac output with dopamine or dobutamine during one-lung ventilation [PDF]

, 2004
Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsTheoretically, if the cardiac output were increased in the presence of a given intrapulmonary shunt, the arterial saturation should improve as the ...
Furman W.R., Karzai W., Karzai W., Marin J.L., Russell W.J.   +4 more
core   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source