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Molecular Oncology, Volume 19, Issue 5, Page 1371-1385, May 2025.Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa +13 more
wiley +1 more source
Anaemia and Hypoproteinaemia in Pregnant Sheep during Anaesthesia
Animals, 2019 The aim of this study was to document the packed cell volume (PCV), haemoglobin concentration and total protein concentration of maternal blood before, during and after anaesthesia.
Gabrielle C. Musk +2 more
doaj +1 more source
Anaesthesia Fluid Detection in 3D Contrast Enhanced Ultrasound Image [PDF]
, 2011 Ultrasound medical image has disadvantage on displaying anaesthesia fluid due to its low intensity. Using contrast agent to enhance brightness of fluid area makes it possible to extract fluid area from acquired 3D image. This paper proposes
Alkaff, Dalily
core
Molecular Oncology, Volume 19, Issue 5, Page 1299-1309, May 2025.Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen +6 more
wiley +1 more source
Journal of Family Medicine and Primary Care, 2021 Anaesthetic management of cardiac disorders in pregnancy has always been complicated and challenging. A rare but extremely fatal entity, peripartum cardiomyopathy (PPCM) is a life-threatening disease affecting the parturient with mortality rates as high ...
Seelora Sahu +3 more
doaj +1 more source
Chaos-modified detrended moving average methodology for monitoring the depth of anaesthesia [PDF]
, 2013 This paper proposes a new method to monitor the depth of anaesthesia (DoA) based on the EEG signal. This approach firstly uses discrete wavelet transform (DWT) to to remove the spikes and the low frequency noise from raw EEG signals. After de-noising the
Li, Yan, Nguyen-Ky, T., Wen, Peng
core
Molecular Oncology, Volume 19, Issue 5, Page 1452-1470, May 2025.Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti +8 more
wiley +1 more source
Future directions in regional anaesthesia: not just for the cognoscenti
Anaesthesia, 2019 Einstein is, of course, referring to a subconscious behavioural pattern that is currently afflicting many aspects of modern medicine: complexity bias. This is the belief that something is better if it is more complicated.
L. R. Turbitt +2 more
semanticscholar +1 more source
Post-cardiac transplant recipient: Implications for anaesthesia
Indian Journal of Anaesthesia, 2017 The annual heart transplant rate is gradually increasing worldwide. A proportion of this patient population present for an elective or emergency surgery which may or may not be related to the transplanted heart.
Minati Choudhury
doaj +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source