Results 101 to 110 of about 35,970 (259)

Neutrophil‐to‐lymphocyte ratio for risk stratification in acute myocarditis across the left ventricular ejection fraction spectrum

open access: yesEuropean Journal of Heart Failure, EarlyView.
Illustration defining the criteria for high‐risk acute myocarditis (AM), incorporating haemodynamic compromise, life‐threatening arrhythmias, and reduced left ventricular ejection fraction (LVEF <40%). Neutrophil‐to‐lymphocyte ratio (NLR) ≥4 is an independent risk marker, including among patients with preserved LVEF (≥50%) at presentation, where ...
Cristina Madaudo   +37 more
wiley   +1 more source

An Economic Comparison of Treatment Strategies with Anakinra in Systemic Juvenile Idiopathic Arthritis (sJIA)

open access: yesOpen Access Rheumatology: Research and Reviews, 2021
Ash Bullement,1 Emma S Knowles,1 Merel Langenfeld,2 Gil Reynolds Diogo,3 Jameel Nazir,4 Daniel Eriksson4 1Delta Hat, Nottingham, UK; 2Sobi, Woluwe-Saint-Lambert, Belgium; 3Sobi, Cambridge, UK; 4Sobi, Stockholm, SwedenCorrespondence: Daniel Eriksson Email
Bullement A   +5 more
doaj  

Scanning for therapeutic targets within the cytokine network of idiopathic inflammatory myopathies [PDF]

open access: yes, 2015
The idiopathic inflammatory myopathies (IIM) constitute a heterogeneous group of chronic disorders that include dermatomyositis (DM), polymyositis (PM), sporadic inclusion body myositis (IBM) and necrotizing autoimmune myopathy (NAM).
De Paepe, Boel, Zschüntzsch, Jana
core   +3 more sources

Induction of WNT16 via peptide-mRNA nanoparticle-based delivery maintains cartilage homeostasis [PDF]

open access: yes, 2020
Osteoarthritis (OA) is a progressive joint disease that causes significant disability and pain and for which there are limited treatment options. We posit that delivery of anabolic factors that protect and maintain cartilage homeostasis will halt or ...
Akk, Antonina   +6 more
core   +2 more sources

Comparison of the effects of erythropoietin and anakinra on functional recovery and gene expression in a traumatic brain injury model

open access: yesFrontiers in Pharmacology, 2013
The goal of this study was to compare the effects of two inflammatory modulators, erythropoietin (EPO) and anakinra, on functional recovery and brain gene expression following a cortical contusion impact (CCI) injury.
Gail D Anderson   +7 more
doaj   +1 more source

International Retrospective Chart Review of Treatment Patterns in Severe Familial Mediterranean Fever, Tumor Necrosis Factor Receptor–Associated Periodic Syndrome, and Mevalonate Kinase Deficiency/Hyperimmunoglobulinemia D Syndrome [PDF]

open access: yes, 2016
Objective: Periodic fever syndrome (PFS) conditions are characterized by recurrent attacks of fever and localized inflammation. This study examined the diagnostic pathway and treatments at tertiary centers for familial Mediterranean fever (FMF), tumor ...
Cantarini, L   +19 more
core   +2 more sources

Development of an R script for simple lipidomic and metabolomic data analysis [PDF]

open access: yes, 2020
Background: Metabolomic and lipidomic studies generate vast quantities of data that are often analysed in a closed software environment with little to no access to the underlying algorithms.
Alshammari, Suad   +4 more
core   +1 more source

A child with resistant Kawasaki disease successfully treated with anakinra: a case report [PDF]

open access: yes, 2018
Background: Kawasaki disease (KD) is an acute self-limited systemic vasculitis of unknown etiology. Intravenous immunoglobulin (IVIG) is an effective treatment and decreases the risk of cardiac complications to less than 5%. In spite of its effectiveness,
Antón López, Jordi   +7 more
core   +1 more source

European Trauma Policy: A Systematic Review of European Union Institutions and Legislation Addressing Orthopedic Surgery and Traumatology During and After the COVID‐19 Pandemic

open access: yesWorld Medical &Health Policy, EarlyView.
ABSTRACT The COVID‐19 pandemic had a detrimental impact on healthcare provision globally and in the European Union (EU). This paper investigates european health policy oriented towards orthopedics and traumatology since the onset of the pandemic. A search of peer–reviewed literature and European Union legislation and scientific databases has been ...
Christos Tsagkaris   +3 more
wiley   +1 more source

Low ICU Admission and Excellent Outcomes in MIS‐C: A Swedish Study From an Open Society

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim During the COVID‐19 pandemic, Sweden chose a more open public health approach. A general concern was that this approach would affect the population negatively. We describe the Swedish national MIS‐C cohort and risk factors for severe disease defined as admission to the intensive care unit and cardiogenic shock.
Petra Król   +13 more
wiley   +1 more source

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