Results 101 to 110 of about 27,150 (219)
Blau Syndrome (Juvenile Systemic Granulomatosis): State‐Of‐The‐Art Review
Pediatric Dermatology, EarlyView.ABSTRACT Blau syndrome (BlauS) is a rare pediatric autoinflammatory disorder due to NOD2 gain‐of‐function pathogenic variants characterized by a triad of granulomatous dermatitis, arthritis, and uveitis, which can progress to systemic complications if untreated.
Ou Jia (Emilie) Wang +3 more
wiley +1 more source
Hepatotoxicity due to tocilizumab and anakinra in rheumatoid arthritis: two case reports
International Journal of General Medicine, 2011 Mahmud Mahamid1,3, Kalman Paz3, Rifaat Safadi1,21Liver Unit, Holy Family Hospital, Nazareth, Israel; 2Hadassah Medical Center, 3Shaare Zedek Medical Center, Jerusalem, IsraelAbstract: Elevation of liver enzymes in patients with rheumatoid arthritis ...
Mahamid M, Paz K, Safadi R
doaj
ACR Open Rheumatology, 2020 Macrophage activation syndrome (MAS) and hemophagocytic lymphohistiocytosis (HLH) are increasingly recognized as being on a continuum of cytokine storm syndromes, with different initiating pathways culminating in cytotoxic dysfunction and uncontrolled ...
Theresa L. Wampler Muskardin
doaj +1 more source
Defining the optimal biological monotherapy in rheumatoid arthritis: a systematic review and meta-analysis of randomised trials [PDF]
, 2016 Objectives To summarize and compare the benefits and harms of biological agents used as monotherapy for rheumatoid arthritis (RA) in order to inform decisions for patients who are intolerant to conventional DMARD therapy.
Bliddal, Henning +12 more
core +2 more sources
Autoimmune Diseases: Molecular Pathogenesis and Therapeutic Targets
MedComm, Volume 6, Issue 7, July 2025.This review provides a comprehensive overview of common autoimmune diseases, details clinical manifestations and summarizes the pathogenesis, including the breakdown of immune tolerance, initiation of autoimmune responses, and their progressive amplification.
Xiaoshuang Song +9 more
wiley +1 more source
Journal of Health Economics and Outcomes Research, 2013 **Background:** Cryopyrin-associated periodic syndromes (CAPS) is a group of rare autoinflammatory diseases. Little is known about the burden of disease, patients’ views on treatment, and adverse events (AEs) with current therapy.
Helen J. Lachmann +5 more
doaj +1 more source
Role of Interleukin-1 in Radiation-Induced Cardiomyopathy [PDF]
, 2015 Thoracic X-ray therapy (XRT), used in cancer treatment, is associated with increased risk of heart failure. XRT-mediated injury to the heart induces an inflammatory response leading to cardiomyopathy.
Abbate, Antonio +9 more
core +3 more sources
Acta Physiologica, Volume 241, Issue 7, July 2025.ABSTRACT Aim Timely myocardial reperfusion is essential for restoring blood flow to post‐ischemic tissue, thereby reducing cardiac injury and limiting infarct size. However, this process can paradoxically result in additional, irreversible myocardial damage, known as myocardial ischemia–reperfusion injury (MIRI).
Anna De Bartolo +3 more
wiley +1 more source
Cardiology Research and Practice, 2016 Recurrent pericarditis is a complication of acute pericarditis in 20–30% of the patients and is usually idiopathic in nature. The underlying pathogenesis of this condition remains unclear, although immune-mediated mechanisms seem likely.
Shankar Baskar +2 more
doaj +1 more source
Clinical Case Reports, 2020 The biological anakinra appears promising to halt cytokine storm syndrome seen in severe courses of COVID‐19. However, immunosuppression with anakinra may facilitate sepsis, necessitating continuous screening for bacterial superinfections.
Leonard Kaps +5 more
doaj +1 more source