Results 111 to 120 of about 22,540 (195)

CSF1R and IL1R1 inhibitors synergistically attenuate the early pathogenesis of traumatic brain injury in mice

Neurotherapeutics
There is an unmet need in the treatment of traumatic brain injury (TBI), a leading cause of death and disability. Colony stimulating factor 1 receptor (CSF1R) and interleukin 1 receptor type 1 (IL1R1) are critical regulators of TBI-associated ...
Sudena Wang, Yong Wang, Jenny Strehle, Isa Wernersbach, Ermis Papakonstantinou, Pawit Somnuke, Katharina Ritter, Matthias Klein, Irmgard Tegeder, Michael K.E. Schäfer   +9 more
doaj   +1 more source

Trial of Anakinra in Secondary Hemophagocytic Lymphohystiocytosis

, 2019
Background: Hemophagocytic lymphohystiocytosis (HLH) is is an uncommon yet potentially devastating systemic disease, arising from uncontrolled activation of the immune system. Secondary HLH can be triggered by malignancy, metabolic disease and infection.
Merchant, Zahra, Ray, Anish, Perez, Maria, Guirola, Ricardo   +3 more
core  

Lung-Predominant Hyperinflammatory Syndrome in Therapy-Related Myelodysplastic Syndrome Responsive to Interleukin-1 Blockade. [PDF]

Hematol Rep
Smith Q, Arar-Cauley A.
europepmc   +1 more source

Comparative associations of Anakinra and Tocilizumab initiation with in-hospital mortality in severe COVID-19: A single-center sequential cohort study. [PDF]

PLoS One
Avsar FN, Kılıcaslan N, Sahutoglu T.
europepmc   +1 more source

IL-1 Blockade to Resolve Persistent Inflammation After STEMI. [PDF]

JACC Basic Transl Sci
Del Buono MG, Golino M, Abbate A.
europepmc   +1 more source

Early neurologic response predicts outcomes after anakinra for immune effector cell-associated neurotoxicity syndrome. [PDF]

Blood Adv
Liang EC, Kungwankiattichai S, Wu X, Voutsinas J, Macero D, Khouderchah C, Qiao Y, Jeon Y, Basom R, Huang JJ, Portuguese AJ, Kimble EL, Hirayama AV, Shadman M, Chen AI, Desai A, Hayes-Lattin B, Meyers G, Bastola S, Rai M, Leonard J, Trussell J, Stomberg C, Spurgeon SE, Okada C, Shree T, Silbermann R, Medvedova E, Ratterree B, Bixler R, Williamson S, Phan C, Ahrenkiel R, Wu Q, Maziarz RT, Gauthier J.   +35 more
europepmc   +1 more source

Comparative Protective Effects of Anakinra and Tocilizumab in Experimental Ocular Ischemic Syndrome. [PDF]

Int J Mol Sci
Karimov S, Sezgin ET, Mammadov R, Suleyman B, Yaqudov K, Yazici GN, Coban TA, Suleyman H, Bayrakceken K.   +8 more
europepmc   +1 more source

Effect of anakinra on cytokine storm during sepsis-induced multiple organ dysfunction syndrome: case report and preclinical investigation. [PDF]

Front Immunol
Blade RM, Lecher SP, Umstead TM, Chroneos ZC, Riccio-Baum C, Allie SR, Hahn TJ, McKeone DJ, Ericson JE, DeMartini T, Spear D, Halstead ES.   +11 more
europepmc   +1 more source

Microparticles Expressing IL-1β Are Linked to Neuroinflammation and Cognitive Decline After Carbon Monoxide Poisoning. [PDF]

Int J Mol Sci
Arya AK, Sethuraman K, Waddell J, Bhat AR, Imtiyaz Z, Walia D, Liang Y, Cha YS, Lee Y, Moayedi S, Sward D, Thom SR.   +11 more
europepmc   +1 more source

Case Report: From idiopathic recurrent pericarditis to systemic Behçet's Disease: unmasking a unified IL-1-driven autoinflammatory phenotype. [PDF]

Front Immunol
Emanuele B, Angela M, Germinario C, Francesca C, Silvia B, Stefano M, Antonio G, Giuseppina M, Maria MA, Sara R, Elisabetta G, Stella M, Francesco P, Martina S, Sarah D, Giulia A, Caterina G, Patrizia RQ, Antonio B.   +18 more
europepmc   +1 more source