Results 131 to 140 of about 31,861 (267)

Anakinra and dexamethasone treatment of idarubicin‐induced mucositis and diarrhoea in rats [PDF]

, 2023
Fredrik Kullenberg, Karsten Peters, Markus Sjöblom, Femke Heindryckx, David Dahlgren, Hans Lennernäs   +5 more
openalex   +1 more source

CAR‐T Cells: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 5, May 2026.
This graphical abstract outlines the current status, challenges, and future prospects of CAR‐T cells. The biological basis of CAR‐T cell therapy is the elegant redirection of adaptive immunity. Its initial successes have exposed a landscape of multifaceted challenges.
Aya Sedky Adly, Guillaume Cartron, Afnan Sedky Adly, Jean‐Christophe Egea, Pierre‐Yves Collart Dutilleul, Mahmoud Sedky Adly, Martin Villalba   +6 more
wiley   +1 more source

Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management

MedComm, Volume 7, Issue 5, May 2026.
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang, Zijiao Tian, Zhaoquan Wang, Zerui Yang, Ziyao Wang, Zikang Wang, Ziqing Wang, Xingyuan He, Yu Yan, Yuanfeng Gong, Siyuan Xu, Xinyi Li, Guihua Tian   +12 more
wiley   +1 more source

Evaluation of Anakinra Use for CAR T-Cell Related Toxicities

, 2023
Sila D Shalhoub, Jennifer Tejeda, Breanna J Taylor, Prof. Amer Beitinjaneh   +3 more
openalex   +1 more source

Multidisciplinary Approach to Complex Lower Extremity Limb Salvage in Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome: A Case Report

Microsurgery, Volume 46, Issue 4, May 2026.
ABSTRACT Limb salvage using free tissue transfer in patients with rare autoinflammatory syndromes is poorly described, and the safety of microvascular reconstruction in this population remains uncertain. Hereditary pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome is characterized by dysregulated inflammation, pathergy, and impaired ...
Michael M. Talanker, Anthony V. Basta, Tien Do, Robert Tung, Addison Allen, Morgan Martin, Bryan L. Ruygrok, Patrick J. Kellam, Jeffrey G. Trost, Mohin A. Bhadkamkar   +9 more
wiley   +1 more source

Anakinra for dengue patients with hyperinflammation: protocol for a randomized double-blind placebo-controlled trial [version 1; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research
Background Novel host-directed therapies are urgently needed for patients with dengue, particularly those at high risk of developing severe disease.
Angela McBride, Huynh Thi Le Duyen, Nguyen Thanh Phong, Truong Ngoc Trung, Sophie Yacoub, Ronald Geskus, Tran Bang Huyen, Evelyne Kestelyn, Dang Trong Thuan, Nguyen Thi My Linh, Tran Thi Dong Vien, Nguyen Thi Cam Huong, Phan Vinh Tho, Nguyen Minh Nguyet, Vo Thi My Hoa, Nguyen Lam Vuong, Phan Tu Qui, Dong Thi Hoai Tam, James Watson, Huynh Trung Trieu   +19 more
doaj   +1 more source

Adherence in Rheumatoid Arthritis patients assessed with a validated Italian version of the 5-item compliance questionnaire for rheumatology [PDF]

, 2019
OBJECTIVES: The 5-item Compliance Questionnaire for Rheumatology (CQR5) proved reliability and validity in respect of identification of patients likely to be high adherers (HAs) to anti-rheumatic treatment, or low adherers (LAs), i.e ...
Astorri, D., Azzolina , D., Botsios, C., Done, John, Doria, A, Favero, M, Friso, L, Gregori, D, Ometto, Francesca, Raffeiner, B.   +9 more
core  

Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy [PDF]

, 2021
Frank L. van de Veerdonk, Giorgia Renga, Marilena Pariano, Marina Maria Bellet, Giuseppe Servillo, Francesca Fallarino, Antonella De Luca, Rossana G. Iannitti, Danilo Piobbico, Marco Gargaro, Giorgia Manni, Fiorella D’Onofrio, Claudia Stincardini, Luigi Sforna, Monica Borghi, Marilena Castelli, Stefania Pieroni, Vasileios Oikonomou, Valeria Rachela Villella, Matteo Puccetti, Stefano Giovagnoli, Roberta Galarini, Carolina Barola, Luigi Maiuri, Maria Agnese Della Fazia, Barbara Cellini, Vincenzo Nicola Talesa, Charles A. Dinarello, Claudio Costantini, Luigina Romani   +29 more
openalex   +1 more source

Human Cytomegalovirus Infection in Haematopoietic Stem Cell Transplant Recipients and CAR T Cell Recipients – PART 1: Risk Factors, Clinical Impact and Immune Response

Reviews in Medical Virology, Volume 36, Issue 3, May 2026.
ABSTRACT Human cytomegalovirus (HCMV) is one of the most important opportunistic pathogens in immunocompromised individuals, including allogeneic haematopoietic stem cell transplant (allo‐HSCT) recipients. In allo‐HSCT, HCMV seropositivity of the recipient and donor is associated with inferior survival outcomes, and post‐transplant HCMV reactivation is
Danya Kaplan, Emily Blyth, Gaurav Sutrave, Michelle K. Yong, David J. Gottlieb, Allison Abendroth, Barry Slobedman, Lauren Stern   +7 more
wiley   +1 more source

Current evidence on the use of anakinra in COVID-19

, 2022
Elnaz Khani, Marzieh Shahrabi, Haleh Rezaei, Fariba Pourkarim, Hoda Afsharirad, Mohammad Solduzian   +5 more
openalex   +2 more sources