Results 111 to 120 of about 27,150 (219)

A large pericardial effusion and bilateral pleural effusions as the initial manifestations of Familial Mediterranean Fever [PDF]

, 2015
Familial Mediterranean Fever (FMF) is a condition characterized by recurrent febrile poly-serositis. Typical presentations of the disease include episodes of fever, abdominal pain and joint pains. Chest pain is a less common presentation.
Cassar Demarco, Daniela, Coleiro, Bernard, Mallia, Carmel, Mifsud, Simon, Schembri, Emma Louise   +4 more
core  

Treatment of adult-onset Still's disease: a review [PDF]

, 2014
Adult-onset Still's disease (AOSD) is a rare inflammatory disorder that has been recently classified as a polygenic autoinflammatory disorder. The former classification, based on the disease course, seems to be quite dated.
Gerfaud-Valentin, M., Henry, T., Jamilloux, Y., Seve, P.   +3 more
core   +2 more sources

Inflammation in atherosclerotic cardiovascular disease: From diagnosis to treatment

European Journal of Clinical Investigation, Volume 55, Issue 7, July 2025.
Inflammation in atherosclerotic cardiovascular disease. Residual inflammatory risk (RIR), defined by high‐sensitive C‐reactive protein (hsCRP) concentration of ≥2 mg/L, represents a strong predictor of future atherosclerotic cardiovascular disease (ASCVD) events. Although increased hsCRP values ≥2 mg/L might be detected in every three out of five ASCVD
Natalie Arnold, Wolfgang Koenig
wiley   +1 more source

Impact of an Interleukin-1 Receptor Antagonist and Erythropoietin on Experimental Myocardial Ischemia/Reperfusion Injury

The Scientific World Journal, 2012
Background. Revascularization of infarcted myocardium results in release of inflammatory cytokines mediating myocardial reperfusion injury and heart failure. Blockage of inflammatory pathways dampens myocardial injury and reduces infarct size.
Christina Grothusen, Angelika Hagemann, Tim Attmann, Jan Braesen, Ole Broch, Jochen Cremer, Jan Schoettler   +6 more
doaj   +1 more source

Role of epicardial adipose tissue in heart failure with preserved ejection fraction: An emerging molecular mechanism and therapeutic potential

Obesity Reviews, Volume 26, Issue 7, July 2025.
Summary With the evolving landscape of diseases, heart failure with preserved ejection fraction (HFpEF) now encompasses more than half of all heart failure patients. This condition is clinically diverse, involving multiple organ systems and often occurring alongside the aging process.
Zhongwen Qi, Dan Wu, Zhipeng Yan, Qing Wang, Yiming Li, Junnan Zhao, Fengqin Xu   +6 more
wiley   +1 more source

Anakinra or high-dose corticosteroids in COVID-19 pneumonia patients who deteriorate on low-dose dexamethasone: an observational study of comparative effectiveness

International Journal of Infectious Diseases, 2023
Objectives: To assess whether escalating to high-dose corticosteroids or anakinra compared with continuing low-dose corticosteroids reduced mortality in patients with severe COVID-19 whose respiratory function deteriorated while receiving dexamethasone 6
Annette Langer-Gould, Stanley Xu, Laura C. Myers, Aiyu Chen, John D. Greene, Beth Creekmur, Katia Bruxvoort, John L. Adams, Vincent Liu, Michael K. Gould   +9 more
doaj  

Erythematous nodes, urticarial rash and arthralgias in a large pedigree with NLRC4-related autoinflammatory disease, expansion of the phenotype [PDF]

, 2016
Autoinflammatory disorders (AID) are a heterogeneous group of diseases, characterized by an unprovoked innate immune response, resulting in recurrent or ongoing systemic inflammation and fever1-3.
Blokx, W. A. M., Boes, M., de Koning, H. D., de Kovel, C., Frenkel, J., Giltay, J., Oberndorff, K., Schalkwijk, J., Simon, A., van Gijn, M. E., van Kempen, T. S., van Steensel, M. A. M., van Well, G. T. J., Volker-Touw, C. M. L.   +13 more
core   +2 more sources

Unveiling VEXAS Syndrome: When Skin Manifestations and Monoclonal Gammopathy Precede Myeloid‐Lineage Hematologic Abnormality

ACR Open Rheumatology, Volume 7, Issue 6, June 2025.
VEXAS (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) syndrome is a rare disorder caused by somatic UBA1 gene mutations, characterized by autoinflammation and hematologic abnormalities, particularly affecting myeloid‐lineage progenitors. Sensitive markers include macrocytic anemia, vacuolization of bone marrow precursors, and myelodysplasia.
Laura Di Centa, Simone Longhino, Valeria Manfrè, Stefania Sacco, Luca Quartuccio   +4 more
wiley   +1 more source

A child with resistant Kawasaki disease successfully treated with anakinra: a case report [PDF]

, 2018
Background: Kawasaki disease (KD) is an acute self-limited systemic vasculitis of unknown etiology. Intravenous immunoglobulin (IVIG) is an effective treatment and decreases the risk of cardiac complications to less than 5%. In spite of its effectiveness,
Antón López, Jordi, Franch, N., Gelman, A., Palacios, J. R., Rivera, J., Rudi, N., Sánchez Manubens, Judith, Teodoro, S.   +7 more
core   +1 more source

Advancing FIRES Treatment: The Potential of Intrathecal Dexamethasone

Annals of the Child Neurology Society, Volume 3, Issue 2, Page 115-120, June 2025.
ABSTRACT Background Febrile infection‐related epilepsy syndrome (FIRES) is a rare, devastating epilepsy syndrome characterized by refractory status epilepticus following a febrile illness. Patient Description We describe a 12‐year‐old girl with FIRES who exhibited a remarkable clinical and electrographic response to intrathecal dexamethasone (IT‐DEX ...
Carol Park, Douglas R. Nordli III, Mohamed Taha, Henry David, Shawn Kacker, Tareq Kass‐Hout, Sonam Thind, Aurelie Hanin, Sana Said, Hiba A. Haider, Douglas R. Nordli Jr.   +10 more
wiley   +1 more source