Results 81 to 90 of about 27,150 (219)
Immunosuppressants and risk of Parkinson disease [PDF]
, 2018 We performed a population-based case-control study of United States Medicare beneficiaries age 60-90 in 2009 with prescription data (48,295 incident Parkinson disease cases and 52,324 controls) to examine the risk of Parkinson disease in relation to use ...
Camacho-Soto, Alejandra +5 more
core +2 more sources
Acta Ophthalmologica, EarlyView.Abstract Purpose To assess and compare the characteristics, therapy interventions, occurrence of uveitis and ocular complications in children with juvenile idiopathic arthritis (JIA) screened and examined for uveitis in Gothenburg, Sweden, over 20 years.
Pia Lundgren +7 more
wiley +1 more source
Cell Transplantation, 2014 Pretreatment culture before islet transplantation represents a window of opportunity to ameliorate the pro-inflammatory profile expressed by human β-cells in duress.
Afaf Sahraoui +5 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding +5 more
wiley +1 more source
Frontiers in Pharmacology, 2013 The goal of this study was to compare the effects of two inflammatory modulators, erythropoietin (EPO) and anakinra, on functional recovery and brain gene expression following a cortical contusion impact (CCI) injury.
Gail D Anderson +7 more
doaj +1 more source
Chronic inhibition of endoplasmic reticulum stress and inflammation prevents ischaemia-induced vascular pathology in type II diabetic mice [PDF]
, 2012 Endoplasmic reticulum (ER) stress and inflammation are important mechanisms that underlie many of the serious consequences of type II diabetes. However, the role of ER stress and inflammation in impaired ischaemia-induced neovascularization in type II ...
A. Amin +9 more
core +3 more sources
Type 1 Diabetes: A Guide to Autoimmune Mechanisms for Clinicians
Diabetes, Obesity and Metabolism, EarlyView.Abstract Type 1 diabetes (T1D) results from the destruction of pancreatic beta cells by autoreactive T lymphocytes, leading to insulin deficiency and lifelong insulin dependence. It develops in genetically predisposed individuals, triggered by environmental or immunological factors.
François‐Xavier Mauvais +1 more
wiley +1 more source
Neonatal treatment of CINCA syndrome. [PDF]
, 2014 : Chronic Infantile Neurological Cutaneous Articular (CINCA) syndrome, also called Neonatal Onset Multisystem Inflammatory Disease (NOMID) is a chronic disease with early onset affecting mainly the central nervous system, bones and joints and may lead to
Berthet, G. +6 more
core +3 more sources
Recent advances in multimodality imaging‐guided therapy in pericarditis
European Journal of Clinical Investigation, EarlyView.Multiple imaging targets have been identified as essential biomarkers to confirm pericardial thickening, edema, neovascularization, inflammation, fibrosis/calcification, cardiac tamponade physiology, and constriction. This novel approach is called imaging‐guided therapy, which guides anti‐inflammatory therapy, assesses treatment response, assists in ...
Joseph El Roumi +4 more
wiley +1 more source
Anakinra and related drugs targeting interleukin-1 in the treatment of cryopyrin-associated periodic syndromes [PDF]
, 2014 Anakinra is an interleukin (IL) receptor antagonist that works by blocking the biological activity of IL-1 by competitively inhibiting binding of IL-1 to the type 1 interleukin receptor.
Bachove, Inessa, Chang, Christopher
core +2 more sources