Results 1 to 10 of about 620,538 (366)

Local excision for patients with stage I anal canal squamous cell carcinoma can be curative [PDF]

Journal of Gastrointestinal Oncology, 2019
Background Definitive concurrent chemoradiation is the current standard of care for all stage I anal canal squamous cell carcinoma. Local excision as primary treatment for selected stage I lesions has been reported in the literature but is not currently ...
Sakti Chakrabarti, Zhaohui Jin, Brandon M. Huffman, Siddhartha Yadav, Rondell P. Graham, Dora Lam‐Himlin, Amy L. Lightner, Christopher L. Hallemeier, Amit Mahipal   +8 more
openalex   +2 more sources

A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalised medicine. [PDF]

British Journal of Cancer, 2018
Primary adenocarcinoma of the anal canal is a rare and aggressive gastrointestinal disease with unclear pathogenesis. Because of its rarity, no clear clinical practice guideline has been defined and a targeted therapeutic armamentarium has yet to be ...
A Purkayastha, A Umar, AA Wright, Alizee Lebeau, Aurelie Poncin, Benjamin Koopmansch, BJ Kocjan, C Martel de, C Mund, Charles M Quick, Christiane Mougin, Christopher P Crum, CS Karapetis, D Leonard, D Meulendijks, David Guenat, Diane Bruyere, DJ Jonker, DK Chan, E Serup-Hansen, EC Pirog, EJ Yang, Elodie Hendrick, F Coppede, Franck Monnien, Frederic Lambert, GJ Chang, H Wang, J Berlin, J Couzin-Frankel, J Mirkovic, JB Carpenter, Jean-Luc Prétet, JM Xu, Karin Segers, Laurence de Leval, Lucine Vuitton, M Basik, M Durst, M Ferrer Marquez, M Herfs, M Herfs, M Herfs, M Herfs, M Herfs, M Lisovsky, M Matsunaga, M Papagikos, M Yamauchi, ME Abel, Michael Herfs, Nathalie Piazzon, O Buhard, O Buhard, Olivier Peulen, P Hubert, Pascale Hubert, Patrick Roncarati, Philippe Delvenne, RD James, S Anwar, S Nagao, S Rajendra, S Valmary-Degano, SE Matlung, Severine Valmary-Degano, T Goto, T Sakamoto, V Heinemann, V Karantza, Vincent Bours, William Penny, Y Belkacemi   +72 more
core   +2 more sources

Long-term outcomes after surgical dissection of inguinal lymph node metastasis from rectal or anal canal adenocarcinoma

BMC Cancer, 2019
Background The 8th edition of the tumor-node-metastasis (TNM) classification classifies inguinal lymph nodes as regional lymph nodes for anal canal carcinoma but non-regional lymph nodes for rectal carcinoma.
Taro Tanabe, Dai Shida, Sho Komukai, Yuya Nakamura, Shunsuke Tsukamoto, Yukihide Kanemitsu   +5 more
doaj   +2 more sources

Surveillance of Anal Canal Cancers [PDF]

Surgical Oncology Clinics of North America, 2017
Anal squamous cell cancer is most frequently a locoregional disease that is amenable to curative therapy in a majority of fit patients. Complete response rates after chemoradiotherapy (CRT) are good, with up to 75% of patients with no evidence of relapse on surveillance.
Adams, Richard
openaire   +6 more sources

New anatomical insight into the muscular structure of the anal canal: revealing Treitz muscle as a directional shift of the internal anal sphincter [PDF]

Annals of Coloproctology
Purpose Understanding the muscular structure of the anal canal is crucial for the diagnosis and treatment of anorectal diseases. Treitz muscle is a vital yet poorly understood component.
Satoru Muro, Kumiko Yamaguchi, Naoko Inoshita, Yasuo Nakajima, Danyo Jennifer Edinam, Akimoto Nimura, Keiichi Akita   +6 more
doaj   +2 more sources

Early Squamous Cell Carcinoma of the Anal Canal Resected by Endoscopic Submucosal Dissection

Case Reports in Gastroenterology, 2015
The standard treatment approach for squamous cell carcinoma (SCC) of the anal canal includes abdominoperineal resection and chemoradiotherapy. However, there are currently very few reports of early SCC of the anal canal resected by endoscopic submucosal ...
Yuzuru Tamaru, Shiro Oka, Shinji Tanaka, Yuki Ninomiya, Naoki Asayama, Kenjiro Shigita, Soki Nishiyama, Nana Hayashi, Koji Arihiro, Kazuaki Chayama   +9 more
doaj   +2 more sources

Adenocarcinoma of the anal canal: A report of two cases with review of literature

Indian Journal of Pathology and Microbiology, 2016
Adenocarcinoma of the anal canal accounts for about 20% of all anal canal cancers. It is subclassified into two types. (1) Colorectal type, which arises from the mucosa above dentate line and (2) extramucosal type, which includes adenocarcinoma arising ...
Medha Pradip Kulkarni, Yasmin Altaf Momin, Amitkumar Bapuso Pandav, Kalpana Ranjitsingh Sulhyan   +3 more
doaj   +2 more sources

Anal Canal Melanoma: Challenging the Odds [PDF]

Case Reports in Oncology
Introduction: Anal canal melanoma is a rare form of both anal cancer and skin melanoma, representing 1% of all anal cancers. Diagnosis is often made at an advanced disease stage.
Sara Magno, Hugo Nunes
doaj   +2 more sources

Anal Canal Adenocarcinoma [PDF]

Definitions, 2020
An anal adenocarcinoma arising from the anal canal mucosa. Morphologically, it resembles the adenocarcinoma which arises from the colorectal glandular epithelium.
openaire   +2 more sources

Efficacy of prostatectomy using a Retzius‐sparing approach as an additional excision in anal canal carcinoma after brachytherapy for prostate adenocarcinoma [PDF]

IJU Case Reports
Introduction Standard treatments for squamous cell carcinoma of the anal canal include chemoradiotherapy and surgical resection. We report a rare case of squamous cell carcinoma of the anal canal with prostate invasion treated with curative surgical ...
Takahiro Yanase, Taku Naiki, Aya Naiki‐Ito, Ryosei Okawa, Sosuke Niwa, Nobuhiko Shimizu, Shuzo Hamamoto, Yoshiaki Fujii, Hiroki Takahashi, Takahiro Yasui   +9 more
doaj   +2 more sources