Results 31 to 40 of about 22,510 (222)
This study demonstrated that a bioabsorbable polymer sheet (BAPS) can regenerate approximately half the circumference of the colon with native‐like structure and function in an experimental setting. As the model involved immediate closure after perforation and did not reproduce peritonitis, caution is required when considering clinical applicability ...
Junpei Takashima +4 more
wiley +1 more source
BACKGROUND: The rectoanal inhibitory reflex has an important rule in the fecal continence mechanism. Alterations in this reflex can be associated with compromised anal sphincteric function.
João Gomes Netinho +4 more
doaj +1 more source
In advanced colorectal cancer, tumors with mature tertiary lymphoid structures (TLS) exhibited abundant infiltration of CD3‐ and CD8‐positive lymphocytes in both primary and metastatic sites, indicating an activated immune response. The presence of mature TLS was also associated with favorable chemotherapy sensitivity and improved prognosis.
Nobuhiro Hosoi +9 more
wiley +1 more source
Anal and Perianal Masses: The Common, the Uncommon, and the Rare
A variety of tumors involve the anal canal because the anal canal forms the transition between the digestive system and the skin, and this anatomical region is made of a variety of different cells and tissues.
Antony Augustine +8 more
doaj +1 more source
Successful Treatment of Metastatic Anal Canal Adenocarcinoma with mFOLFOX6 + Bevacizumab
Anal canal adenocarcinoma is a relatively rare malignancy without established diagnostic and treatment criteria. Case reports of chemotherapy for anal canal adenocarcinoma with distant metastasis are limited, and there is no convincing evidence for ...
Mototsugu Matsunaga +7 more
doaj +1 more source
This study investigated the impact of two‐team surgery on short‐ and long‐term outcomes of transanal total mesorectal excision for rectal cancer. Two‐team surgery has some advantages over one‐team surgery, such as shorter operation time, decreased estimated blood loss, increased number of lymph nodes dissected, and decreased positive distal margin ...
Nobuaki Hoshino +13 more
wiley +1 more source
Abdominoperineal resection (APR) after minimally invasive rectal cancer surgery was associated with significantly higher rates of erectile and early ejaculatory dysfunction compared with anal‐sparing surgery. Although ejaculatory function showed partial recovery over time, erectile dysfunction persisted up to 12 months postoperatively.
Taiki Kajiwara +14 more
wiley +1 more source
Although anal cancer remains rarely diagnosed in the world, its frequency is rising, especially in high-risk groups. The prognosis of advanced anal cancer is poor.
Hengcun Li +4 more
doaj +1 more source
ABSTRACT Aim The National Clinical Database (NCD) of Japan is the largest nationwide registry, covering over 95% of surgeries in the country. This 2022 annual report summarizes the short‐term outcomes of gastroenterological surgeries and discusses trends and insights over the past decade.
Koshi Kumagai +19 more
wiley +1 more source
A novel four quadrant laser sphincterotomy for idiopathic severe anal stenosis
Anal stricture or stenosis, though uncommon, is disabling condition. It affects the quality of life due to pain, bleeding and difficulty in defecation, incontinence or increased frequency.
Ashwin Porwal +2 more
doaj +1 more source

