Results 51 to 60 of about 22,967 (230)

OR-43 - DIVERSIDADE DO HPV NO CANAL ANAL E COLO DO ÚTERO DE MULHERES QUE VIVEM COM HIV

Brazilian Journal of Infectious Diseases
Introdução: A infecção pelo papilomavírus humano (HPV) está associada ao desenvolvimento de câncer nas regiões anogenital e de orofaringe. Pessoas que vivem com HIV apresentam maior risco de infecção por HPV, neoplasia intraepitelial e desenvolvimento de
Élida Mendes de Oliveira, José Antonio Cunha e Silva, Letícia Lintomen, Marcelo Alves Soares, Fabio Leal, Isabel Guimarães, Livia Ramos Goes, Juliana Domett Siqueira   +7 more
doaj   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Anal canal squamous carcinoma

Journal of Coloproctology, 2017
Background: Anal canal carcinoma is a rare neoplasm, representing 2% of the digestive tumors, and the most common is squamous cell carcinoma, with an increasing incidence.
Maricruz Nunes Magalhães, Laura Elisabete Ribeiro Barbosa   +1 more
doaj   +1 more source

Assessing Gammapapillomavirus infections of mucosal epithelia with two broad-spectrum PCR protocols

BMC Infectious Diseases, 2020
Background Human papillomaviruses (HPVs) have been divided into mucosal and cutaneous types according to their primary epithelial tissue tropism. However, recent studies showed the presence of several cutaneous types in mucosal lesions and healthy mucosa
Elisa M. Bolatti, Lea Hošnjak, Diego Chouhy, Pablo E. Casal, María F. Re-Louhau, Hebe Bottai, Kristina Fujs Komloš, Mario Poljak, Adriana A. Giri   +8 more
doaj   +1 more source

Rare Anal Canal Cancer with Secondary Extramammary Paget’s Disease (Pagetoid Spread) Complicated by Squamous Cell Carcinoma of the Skin

Case Reports in Surgery, 2021
A 91-year-old man had a node and erythema in the anal area resistant to treatment. A biopsy of the node in the anus showed atypical cells developing as Paget’s disease, and staining revealed that the cells were CK7-positive, CK20-positive, and GCDFP15 ...
Tatsuki Kusuhara, Takashi Ito, Hiroki Matsuoka, Teruhiro Chohno, Masataka Zozumi, Takamasa Ohnishi   +5 more
doaj   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Grooved Surface of the Obturator Internus Muscle With Two Distinct Adjacent Parts

Clinical Anatomy, EarlyView.
ABSTRACT The specific anatomical features of the obturator internus, particularly those of its medial surface, remain insufficiently characterized. This study investigated the morphology of the obturator internus muscle by focusing on the shape of its medial surface and potential age‐related changes.
Satoru Muro, Junichi Tsuchiya, Takuya Ibara, Akimoto Nimura, Keiichi Akita   +4 more
wiley   +1 more source

The Science, Techniques, and Art of Anal Fistula Treatment

Indian Journal of Colo-Rectal Surgery, 2019
Anal fistula is a diverse disease. There is no single treatment which is effective for all types of anal fistulas. The management of simple anal fistula is straightforward, and a fistulotomy is recommended. However, in complex anal fistula if fistulotomy
Arshad Ahmad
doaj   +1 more source

Basaloid carcinoma of the anal canal [PDF]

Journal of Clinical Pathology, 1967
The pathology and results of treatment of 36 cases of basaloid carcinomas of the anal canal are described. This variant of squamous cell carcinoma of the anal region arises from the entodermal-ectodermal junctional zone of the anal canal at or above the dentate line.
L S, Pang, B C, Morson
openaire   +2 more sources

Extended High‐Risk HPV Genotyping With BD Onclarity Enhances Anal Cancer Screening Among High‐Risk Populations: A Cross‐Sectional Study

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Anal cancer rates are rising among women, immunocompromised individuals, and Men who have sex with Men (MSM), independent of HIV status. While high‐resolution anoscopy remains the diagnostic standard, limited access has increased interest in alternative screening.
Daisy Maharjan, Joshua Waters, Melissa Randolph, Benjamin Shuler, Julie Borum, Sheila Segura   +5 more
wiley   +1 more source