Results 51 to 60 of about 451,678 (252)

Human evolution and the obstetrical dilemma: The pelvic floor hypothesis

The Anatomical Record, EarlyView.
Abstract Human childbirth is mechanically difficult because a large‐headed, broad‐shouldered fetus must pass through a comparatively narrow, twisted bony birth canal. Traditional explanations of this “obstetrical dilemma” emphasize the role of bipedal locomotion in inhibiting the evolution of a wider, more spacious pelvis.
Barbara Fischer, Ekaterina Stansfield
wiley   +1 more source

Characteristics of Anal Fistula Cancer in Patients Who Underwent Surgery: A Nationwide Observational Study Using Diagnosis Procedure Combination Data

Annals of Gastroenterological Surgery
Aim Anal fistula cancer is a rare disease that occurs in
Nobuaki Hoshino, Hiromitsu Kinoshita, Kazutaka Obama, Kiyohide Fushimi, Susumu Kunisawa, Yuichi Imanaka   +5 more
doaj   +1 more source

Assessment of intraspecific skull variation in the Campanian baenid turtle Plesiobaena antiqua

The Anatomical Record, EarlyView.
Abstract Baenids are freshwater paracryptodiran turtles with a fossil record ranging from the Early Cretaceous to the Eocene. The baenid Plesiobaena antiqua is the most common turtle in the Campanian (Late Cretaceous) Dinosaur Park Formation in Canada, but the apparent intraspecific variation remains poorly understood.
Scott Bellotti, Donald D. Brinkman, Serjoscha W. Evers, Walter G. Joyce, Yann Rollot   +4 more
wiley   +1 more source

OR-43 - DIVERSIDADE DO HPV NO CANAL ANAL E COLO DO ÚTERO DE MULHERES QUE VIVEM COM HIV

Brazilian Journal of Infectious Diseases
Introdução: A infecção pelo papilomavírus humano (HPV) está associada ao desenvolvimento de câncer nas regiões anogenital e de orofaringe. Pessoas que vivem com HIV apresentam maior risco de infecção por HPV, neoplasia intraepitelial e desenvolvimento de
Élida Mendes de Oliveira, José Antonio Cunha e Silva, Letícia Lintomen, Marcelo Alves Soares, Fabio Leal, Isabel Guimarães, Livia Ramos Goes, Juliana Domett Siqueira   +7 more
doaj   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Grooved Surface of the Obturator Internus Muscle With Two Distinct Adjacent Parts

Clinical Anatomy, EarlyView.
ABSTRACT The specific anatomical features of the obturator internus, particularly those of its medial surface, remain insufficiently characterized. This study investigated the morphology of the obturator internus muscle by focusing on the shape of its medial surface and potential age‐related changes.
Satoru Muro, Junichi Tsuchiya, Takuya Ibara, Akimoto Nimura, Keiichi Akita   +4 more
wiley   +1 more source

Anal canal squamous carcinoma

Journal of Coloproctology, 2017
Background: Anal canal carcinoma is a rare neoplasm, representing 2% of the digestive tumors, and the most common is squamous cell carcinoma, with an increasing incidence.
Maricruz Nunes Magalhães, Laura Elisabete Ribeiro Barbosa   +1 more
doaj   +1 more source

Assessing Gammapapillomavirus infections of mucosal epithelia with two broad-spectrum PCR protocols

BMC Infectious Diseases, 2020
Background Human papillomaviruses (HPVs) have been divided into mucosal and cutaneous types according to their primary epithelial tissue tropism. However, recent studies showed the presence of several cutaneous types in mucosal lesions and healthy mucosa
Elisa M. Bolatti, Lea Hošnjak, Diego Chouhy, Pablo E. Casal, María F. Re-Louhau, Hebe Bottai, Kristina Fujs Komloš, Mario Poljak, Adriana A. Giri   +8 more
doaj   +1 more source

Rare Anal Canal Cancer with Secondary Extramammary Paget’s Disease (Pagetoid Spread) Complicated by Squamous Cell Carcinoma of the Skin

Case Reports in Surgery, 2021
A 91-year-old man had a node and erythema in the anal area resistant to treatment. A biopsy of the node in the anus showed atypical cells developing as Paget’s disease, and staining revealed that the cells were CK7-positive, CK20-positive, and GCDFP15 ...
Tatsuki Kusuhara, Takashi Ito, Hiroki Matsuoka, Teruhiro Chohno, Masataka Zozumi, Takamasa Ohnishi   +5 more
doaj   +1 more source

Zebrafish ventral gastrula fate map reveals neural crest progenitor domain

Developmental Dynamics, EarlyView.
Abstract Background Fate maps relate progenitor cell positions to later fates and locations of their progeny, revealing early embryonic organization. Previous zebrafish fate maps identified the origin of germ layers and derivative cell fates, but ventral gastrula progenitor domains were not fully resolved. In particular, the neural crest, a multipotent
Elaine E. Kushkowski, Victoria E. Prince
wiley   +1 more source