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Anal Canal Cancer

Diseases of the Colon & Rectum, 2003
This study was designed to obtain an updated population-based perspective on anal canal cancer incidence rates, demographics, and outcomes using a nationwide database. Eight-five percent of all carcinomas of the anus are anal canal cancers, and previous studies suggest that incidence rates may be rising.
Melinda A, Maggard   +2 more
openaire   +2 more sources

Anal Canal Cancer

Medical Radiology, 2014
Physical examination is an important part of the staging and planning process as well as adequate imaging studies. Standard studies include CT of the pelvis to assess the primary tumor and the status of regional lymph nodes. These tumors can be well visualized on PET, so a PET/CT scan is becoming a standard part of staging and planning to help ...
Albert C. Koong, Jose Bazan
exaly   +2 more sources

Current management of anal canal cancer

Current Oncology Reports, 2009
Squamous cell carcinoma of the anal canal historically has been treated with abdominoperineal resection, resulting in high rates of morbidity and local recurrence. Pioneering work led to the finding that radiation therapy (RT) combined with 5-fluorouracil (5-FU) and mitomycin results in high rates of local control and disease-free and colostomy-free ...
Brian G, Czito, Christopher G, Willett
openaire   +2 more sources

Treatment of epidermoid anal canal cancer

The American Journal of Surgery, 1984
Between 1968 and 1979, 183 patients with invasive epidermoid cancer of the anal canal were treated at Institut Curie. There was 156 women, 27 men with a mean age of 67 +/- 11 years (range 40 to 85 years). The initial height of the tumor was less than 4 cm (65 patients), 4 to 6 cm (98 patients), and more than 6 cm (20 patients).
R J, Salmon   +8 more
openaire   +2 more sources

Anal Canal Cancer

2015
Radiation therapy with concurrent chemotherapy is the standard treatment for patients with nonmetastatic squamous cell carcinoma of the anal canal. In the studies that established this approach, high rates of locoregional control have been reported, but the incidence of acute and late toxicity has been significant.
Bradford A. Perez   +3 more
openaire   +1 more source

Combined therapy for cancer of the anal canal

Diseases of the Colon & Rectum, 1981
Nineteen patients with squamous-cell cancer of the anal canal have been treated with combined chemotherapy and radiation therapy, followed by appropriate surgery. The authors are convinced that the combined therapy is effective enough to avoid abdominoperineal resection if disappearance of the lesion is proven by adequate examination and biopsy ...
N D, Nigro   +4 more
openaire   +2 more sources

[Cancer of the anal canal].

Arkhiv patologii, 1985
Seventy-four carcinomas of the anal canal (4,9% of the total number of rectum carcinoma for 1952-1982) were studied, including 45 squamous-cell, 23 adenogenic and 6 undifferentiated carcinomas. Adenogenic carcinomas originated from the rectum mucous membrane over the serrated line; as distinct from carcinomas of other parts of the rectum the mucus ...
V I, Rottenberg, Iu M, Timofeev
openaire   +1 more source

Cancer of the Anal Canal

1990
Cancer of the anus, a pathology of elderly individuals, consists essentially of epidermoid carcinomas located in the anal canal. Lesions of the anal margin are considered skin cancers. Systematic biopsy of all atypical anal lesions is an effective strategy for correct diagnosis.
openaire   +1 more source

Cancer of the Anal Canal

2002
The anal canal is the most extreme segment of the digestive tract and extends proximaliy from the anal margin (which is covered by epidermis) to the rectal mucosa. Since the anal canal is almost entirely covered by squamous epithelium, neoplasms arising in this segment are usually keratinizing or non-keratinizing squamous cell carcinomas, whose biology
openaire   +1 more source

Current Management of Anal Canal Cancer

Seminars in Oncology, 2005
Combined-modality therapy consisting of radiation therapy and 5-fluorouracil plus mitomycin remains the standard treatment for localized anal canal cancer, permitting preservation of organ function and achieving high response and survival rates.
openaire   +2 more sources

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