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Anal Cancer: The Past, Present and Future

open access: yesCurrent Oncology, 2023
Anal cancer is a rare cancer that accounts for about 2% of all gastrointestinal tract malignancies. Among anal cancer, squamous cell cancer is the most common malignancy. The incidence of all stages of anal squamous cell cancer has been increasing. Human
Talha Ashraf Gondal   +5 more
doaj   +3 more sources

Anal cancer: an overview.

open access: yesOncologist, 2007
Learning Objectives After completing this course, the reader will be able to: Discuss the epidemiology of and the risk factors for anal cancer.Outline standard treatment for anal cancer and describe its complications.Understand the issues related to treating HIV-positive patients with anal cancer ...
Hope E, Uronis, Johanna C, Bendell
exaly   +3 more sources

“I just assumed that was the same as colon cancer.” Lack of knowledge about anal HPV infection, anal cancer, and anal cancer screening in older MSM: a qualitative study [PDF]

open access: yesBMC Public Health
Background Antiretroviral treatment has allowed people living with HIV (PLWH) to live longer lives. A high proportion of PLWH are ≥ 50 years of age and identify as men who have sex with men (MSM); MSM who are living with HIV (MSMLWH) are at increased ...
Catherine Nguyen   +7 more
doaj   +2 more sources

Anal cancer screening and the role of clinicians providing gynecologic care: A survey of anal cancer screening knowledge and practice patterns at an urban tertiary medical center in the United States [PDF]

open access: yesPreventive Medicine Reports
Objective: This study aims to assess the current knowledge of anal cancer, screening, and practice patterns among clinicians providing gynecologic care.
Colin B. Russell   +7 more
doaj   +2 more sources

Application of the Cascade of Care Framework to Guide Evidence-Informed Implementation of Anal Cancer Screening Guidelines [PDF]

open access: yesCancer Control
Most squamous cell carcinomas of the anus, or anal cancers, are attributable to persistent infection with the human papillomavirus (HPV), analogous to cervical cancer.
Ann N. Burchell PhD   +5 more
doaj   +2 more sources

Immune landscape and prognostic immune-related genes in KRAS-mutant colorectal cancer patients

open access: yesJournal of Translational Medicine, 2021
Background KRAS gene is the most common type of mutation reported in colorectal cancer (CRC). KRAS mutation-mediated regulation of immunophenotype and immune pathways in CRC remains to be elucidated.
Jungang Liu   +13 more
doaj   +1 more source

Identification of colorectal cancer progression-associated intestinal microbiome and predictive signature construction

open access: yesJournal of Translational Medicine, 2023
Objective The relationship between intestinal microbiome and colorectal cancer (CRC) progression is unclear. This study aims to identify the intestinal microbiome associated with CRC progression and construct predictive labels to support the accurate ...
Jungang Liu   +12 more
doaj   +1 more source

Mesorectal reconstruction with pedicled greater omental transplantation to relieve low anterior resection syndrome following total intersphincteric resection in patients with ultra-low rectal cancer

open access: yesBMC Surgery, 2023
Background Total intersphincteric resection (ISR) is the ultimate anus-preserving surgery for patients with ultra-low rectal cancer (ULRC), which can result in various degrees of anorectal dysfunction.
Jiankun Liao   +6 more
doaj   +1 more source

Feasibility and advantages analyses of wedge resection without mesentery detached approach applied to closure of loop ileostomy

open access: yesBMC Surgery, 2022
Objectives To evaluate the feasibility and advantages of wedge resection plus transverse suture without mesentery detached approach applied to loop ileostomy closure by analyzing the surgical data and the incidence of postoperative complications of ...
Hai-Quan Qin   +5 more
doaj   +1 more source

Organoid: Next-Generation Modeling of Cancer Research and Drug Development

open access: yesFrontiers in Oncology, 2022
Colorectal carcinoma is a highly prevalent and heterogeneous gastrointestinal malignancy. The emergence of organoid technology has provided a new direction for colorectal cancer research.
Jungang Liu   +9 more
doaj   +1 more source

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