Results 11 to 20 of about 89,708 (258)

An integrative analysis revealing POLD2 as a tumor suppressive immune protein and prognostic biomarker in pan-cancer

open access: yesFrontiers in Genetics, 2022
Introduction: POLD2 is an indispensable subunit of DNA polymerase δ, which is responsible for the synthesis of the backward accompanying strand in eukaryotic organisms.
Fengyun Cong   +10 more
doaj   +1 more source

Case Report: Colon malignant tumor caused by retroperitoneal small round cell undifferentiated sarcoma

open access: yesFrontiers in Oncology, 2023
Small round cell undifferentiated sarcoma is a rare and highly invasive group of malignant bone and soft tissue tumors, often associated with a high misdiagnosis rate. The patient in this case was a 34-year-old male who presented with a two-month history
Yuqin Wei   +6 more
doaj   +1 more source

Immunotherapy in Anal Cancer

open access: yesCurrent Oncology, 2023
The incidence and mortality of squamous cell carcinoma of the anus has been gradually increasing globally over the last few decades. The evolution of different modalities, including immunotherapies, has changed the treatment paradigm of metastatic anal cancers.
Natasha Dhawan   +2 more
openaire   +3 more sources

Anatomy of Subpancreatic Transverse Colon Vessel and Its Clinical Significance: An Observational Study

open access: yesFrontiers in Surgery, 2022
PurposeTo observe and count the probability of presence and the anatomy of the vessel arising via the inferior margin of the pancreas and traveling within the transverse mesocolon, and analyze its clinical significance.MethodsPatients who underwent ...
Jiankun Liao   +12 more
doaj   +1 more source

Prognostic and immunological role of SERPINH1 in pan-cancer

open access: yesFrontiers in Genetics, 2022
Background: The SERPINH1 gene plays a vital part in tumorigenesis and development, whereas its potential as an immunotherapy target is still unknown.
Huage Zhong   +12 more
doaj   +1 more source

Upregulation of ADAM12 Is Associated With a Poor Survival and Immune Cell Infiltration in Colon Adenocarcinoma

open access: yesFrontiers in Oncology, 2021
BackgroundA disintegrin and metalloprotease 12 (ADAM12) is a member of the multidomain protein family, but the mechanisms by which it affects prognosis and immune cell infiltration in patients with colon adenocarcinoma (COAD) remain unclear.
Zigao Huang   +17 more
doaj   +1 more source

Development of a Platelet-Related Prognostic Model for Colorectal Cancer

open access: yesFrontiers in Genetics, 2022
Colorectal cancer (CRC) represents one of the most common malignancies with high morbidity worldwide. Growing evidence has suggested that platelets are a fundamental component of the tumor microenvironment and play crucial roles in driving tumor ...
Pengcheng Wang, Wei Zhao, Hailei Cao
doaj   +1 more source

Cancer in Anal Fistulas

open access: yesClinics in Colon and Rectal Surgery, 2023
AbstractFistula-associated anal cancer in Crohn's disease (CD) can be challenging to diagnose and treat. Patients with longstanding fistulas in the setting of CD who present with a sudden change in their symptoms should undergo biopsy under anesthesia with extensive sampling, followed by staging imaging.
Perez, Sean, Eisenstein, Samuel
openaire   +4 more sources

Nomogram for predicting overall survival in stage II‐III colorectal cancer

open access: yesCancer Medicine, 2020
Purpose The overall survival (OS) of patients diagnosed with stage II‐III colorectal cancer (CRC) can vary greatly, even between patients with the same tumor stage.
Jungang Liu   +14 more
doaj   +1 more source

A Combined Epithelial Mesenchymal Transformation and DNA Repair Gene Panel in Colorectal Cancer With Prognostic and Therapeutic Implication

open access: yesFrontiers in Oncology, 2021
BackgroundEpithelial mesenchymal transformation (EMT) and DNA repair status represent intrinsic features of colorectal cancer (CRC) and are associated with patient prognosis and treatment responsiveness. We sought to develop a combined EMT and DNA repair
Xiaoliang Huang   +16 more
doaj   +1 more source

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