Results 21 to 30 of about 3,204,753 (287)

Imaging biomarkers for risk stratification in colorectal and anal cancer [PDF]

, 2020
Introduction: “Imaging biomarkers” (IB) are radiological measurements that predict outcomes. Although IBs have been validated for primary colorectal cancer none are available for predicting disease relapse in colorectal or anal cancer.
Wale, Anita
core   +1 more source

Nomogram for predicting overall survival in stage II‐III colorectal cancer

Cancer Medicine, 2020
Purpose The overall survival (OS) of patients diagnosed with stage II‐III colorectal cancer (CRC) can vary greatly, even between patients with the same tumor stage.
Jungang Liu, Xiaoliang Huang, Wenkang Yang, Chan Li, Zhengtian Li, Chuqiao Zhang, Shaomei Chen, Guo Wu, Weishun Xie, Chunyin Wei, Chao Tian, Lingxu Huang, Franco Jeen, Xianwei Mo, Weizhong Tang   +14 more
doaj   +1 more source

A Combined Epithelial Mesenchymal Transformation and DNA Repair Gene Panel in Colorectal Cancer With Prognostic and Therapeutic Implication

Frontiers in Oncology, 2021
BackgroundEpithelial mesenchymal transformation (EMT) and DNA repair status represent intrinsic features of colorectal cancer (CRC) and are associated with patient prognosis and treatment responsiveness. We sought to develop a combined EMT and DNA repair
Xiaoliang Huang, Xiaoliang Huang, Jungang Liu, Jungang Liu, Jungang Liu, Haizhou Liu, Xianwei Mo, Xianwei Mo, Yongsheng Meng, Yongsheng Meng, Lihua Zhang, Lihua Zhang, Yuqing Deng, Yuqing Deng, Yawei Zhang, Weizhong Tang, Weizhong Tang   +16 more
doaj   +1 more source

Development of a Platelet-Related Prognostic Model for Colorectal Cancer

Frontiers in Genetics, 2022
Colorectal cancer (CRC) represents one of the most common malignancies with high morbidity worldwide. Growing evidence has suggested that platelets are a fundamental component of the tumor microenvironment and play crucial roles in driving tumor ...
Pengcheng Wang, Wei Zhao, Hailei Cao
doaj   +1 more source

Evolution of the Role of Radiotherapy for Anal Cancer

, 2021
Prior to the 1980s, the primary management of localized anal cancer was surgical resection. Dr. Norman Nigro and colleagues introduced neoadjuvant chemoradiotherapy prior to abdominoperineal resection.
James D. Byrne, Jennifer Y. Wo, Edward Christopher Dee   +2 more
core   +1 more source

The acceptability of high resolution anoscopy examination in patients attending a tertiary referral centre

BMC Cancer, 2018
Background High resolution anoscopy (HRA) examination is regarded as the best method for the management of anal high grade squamous intraepithelial lesions to prevent anal squamous carcinoma.
Anke De-Masi, Esther Davis, Tamzin Cuming, Noreen Chindawi, Francesca Pesola, Carmelina Cappello, Susan Chambers, Julie Bowring, Adam N. Rosenthal, Peter Sasieni, Mayura Nathan   +10 more
doaj   +1 more source

Association analysis of gut microbiota with LDL-C metabolism and microbial pathogenicity in colorectal cancer patients

Lipids in Health and Disease
Background Colorectal cancer (CRC) is the most common gastrointestinal malignancy worldwide, with obesity-induced lipid metabolism disorders playing a crucial role in its progression. A complex connection exists between gut microbiota and the development
Mingjian Qin, Zigui Huang, Yongqi Huang, Xiaoliang Huang, Chuanbin Chen, Yongzhi Wu, Zhen Wang, Fuhai He, Binzhe Tang, Chenyan Long, Xianwei Mo, Jungang Liu, Weizhong Tang   +12 more
doaj   +1 more source

ELK4 Promotes Colorectal Cancer Progression by Activating the Neoangiogenic Factor LRG1 in a Noncanonical SP1/3‐Dependent Manner

Advanced Science, 2023
Although the MAPK/MEK/ERK pathway is prevalently activated in colorectal cancer (CRC), MEK/ERK inhibitors show limited efficiency in clinic. As a downstream target of MAPK, ELK4 is thought to work primarily by forming a complex with SRF. Whether ELK4 can
Zhehui Zhu, Yuegui Guo, Yun Liu, Rui Ding, Zhenyu Huang, Wei Yu, Long Cui, Peng Du, Ajay Goel, Chen‐Ying Liu   +9 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Analysis of differences in intestinal flora associated with different BMI status in colorectal cancer patients

Journal of Translational Medicine
Background Overweight is known to be an important risk factor for colorectal cancer (CRC), and the differences in intestinal flora among CRC patients with different BMI status have not been clearly defined.
Yongqi Huang, Xiaoliang Huang, Zhen Wang, Fuhai He, Zigui Huang, Chuanbin Chen, Binzhe Tang, Mingjian Qin, Yongzhi Wu, Chenyan Long, Weizhong Tang, Xianwei Mo, Jungang Liu   +12 more
doaj   +1 more source