Results 21 to 30 of about 89,708 (258)

Anal cancer screening. [PDF]

CMAJ
Grennan T, Salit IE.
europepmc   +3 more sources

The acceptability of high resolution anoscopy examination in patients attending a tertiary referral centre

BMC Cancer, 2018
Background High resolution anoscopy (HRA) examination is regarded as the best method for the management of anal high grade squamous intraepithelial lesions to prevent anal squamous carcinoma.
Anke De-Masi, Esther Davis, Tamzin Cuming, Noreen Chindawi, Francesca Pesola, Carmelina Cappello, Susan Chambers, Julie Bowring, Adam N. Rosenthal, Peter Sasieni, Mayura Nathan   +10 more
doaj   +1 more source

Association analysis of gut microbiota with LDL-C metabolism and microbial pathogenicity in colorectal cancer patients

Lipids in Health and Disease
Background Colorectal cancer (CRC) is the most common gastrointestinal malignancy worldwide, with obesity-induced lipid metabolism disorders playing a crucial role in its progression. A complex connection exists between gut microbiota and the development
Mingjian Qin, Zigui Huang, Yongqi Huang, Xiaoliang Huang, Chuanbin Chen, Yongzhi Wu, Zhen Wang, Fuhai He, Binzhe Tang, Chenyan Long, Xianwei Mo, Jungang Liu, Weizhong Tang   +12 more
doaj   +1 more source

ELK4 Promotes Colorectal Cancer Progression by Activating the Neoangiogenic Factor LRG1 in a Noncanonical SP1/3‐Dependent Manner

Advanced Science, 2023
Although the MAPK/MEK/ERK pathway is prevalently activated in colorectal cancer (CRC), MEK/ERK inhibitors show limited efficiency in clinic. As a downstream target of MAPK, ELK4 is thought to work primarily by forming a complex with SRF. Whether ELK4 can
Zhehui Zhu, Yuegui Guo, Yun Liu, Rui Ding, Zhenyu Huang, Wei Yu, Long Cui, Peng Du, Ajay Goel, Chen‐Ying Liu   +9 more
doaj   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Analysis of differences in intestinal flora associated with different BMI status in colorectal cancer patients

Journal of Translational Medicine
Background Overweight is known to be an important risk factor for colorectal cancer (CRC), and the differences in intestinal flora among CRC patients with different BMI status have not been clearly defined.
Yongqi Huang, Xiaoliang Huang, Zhen Wang, Fuhai He, Zigui Huang, Chuanbin Chen, Binzhe Tang, Mingjian Qin, Yongzhi Wu, Chenyan Long, Weizhong Tang, Xianwei Mo, Jungang Liu   +12 more
doaj   +1 more source

Anal Cancer : A Review

International Journal of Health Sciences, 2012
Anal cancer accounts for only 1.5% of gastrointestinal malignancies but this disease has shown a steady increase in incidence particularly in HIV positive males. The understanding of pathophysiology and treatment of anal cancer has changed radically over last thirty years.
Sajad Ahmad, Salati, Azzam, Al Kadi
openaire   +2 more sources

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

27 Association of anal dysplasia with cervical dysplasia and high-risk HPV subtypes in women

Gynecologic Oncology Reports, 2023
Objectives: High-risk human papillomavirus (hrHPV) infection is a necessary risk factor for cervical and anal dysplasia. Over the last five years, there is increasing evidence that the natural history of hrHPV-induced anal cancer is close to that of ...
Sonal Chaudhari, Sanaz Memarzadeh, Ardis Moe   +2 more
doaj   +1 more source