Results 151 to 160 of about 3,204,753 (287)

Real-world outcomes of pembrolizumab in advanced anal cancer: a nationwide Danish anal Cancer Group report. [PDF]

Acta Oncol
Garm Spindler KL, Hvid CA, Fokdal LU, Wind KL, Jakobsen AV, Eefsen RL, Serup-Hansen E.   +6 more
europepmc   +1 more source

Assessment of Clinical and Immunological Factors of Local Recurrence in Canine Soft Tissue Sarcoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Canine soft tissue sarcomas (STSs) are locally invasive tumours, making local recurrence a major clinical challenge. Time to recurrence (TTR) and associated immune factors remain poorly characterized. This study aimed to characterize the immune microenvironment of canine STS and identify factors associated with TTR.
Kazuki Mizuta, Helene Philibert, Arata Matsuyama   +2 more
wiley   +1 more source

Anal Cancer Screening and High-Resolution Anoscopy: What Surgeons Should Know. [PDF]

ANZ J Surg
Marino MJ, Blacket B, Turner RC, Cuming T, James DRC.   +4 more
europepmc   +1 more source

Vascular, inflammatory and perceptual responses to hot water immersion: Impacts of water depth and temperature in young healthy adults

Experimental Physiology, EarlyView.
Abstract Repeated hot water immersion can improve cardiovascular health; however, the respective effects of distinct immersion protocols remain unclear. Twenty‐two healthy adults completed three 30‐min hot water immersion bouts of different water temperatures and immersion depths (40°C shoulder‐deep immersion, 40‐Shoulder; 42°C waist‐deep immersion, 42‐
Campbell Menzies, Neil D. Clarke, Charles J. Steward, Charles Douglas Thake, Christopher J. A. Pugh, Tom Cullen   +5 more
wiley   +1 more source

Clinicopathologic Features Associated with Survival for Immune Checkpoint Blockade in Patients with Metastatic Anal Cancer

Background/Objectives: Anal cancer is a rare malignancy with limited treatment options. Immune checkpoint inhibitors have shown benefits in some patients with metastatic disease, but predictive factors for immunotherapy response remain undefined.
Eng, Cathy, Wai Chin Foo, Nguyen, Diem V., Foo, Wai Chin, Jocelyn Mitchell, Van K. Morris, Kangyu Lin, Sophia Jacob, Peddireddy, Arjun S., Lisa Scofield, Mitchell, Jocelyn, Diem V. Nguyen, Arjun S. Peddireddy, Cathy Eng, Portier, Shaelynn, Lin, Kangyu, Ryan Huey, Robert A. Wolff, Jane Rogers, Wolff, Robert A., Jacob, Sophia, Shaelynn Portier, Rogers, Jane, Scofield, Lisa, Morris, Van K., Huey, Ryan   +25 more
core   +1 more source

Prognostic impact of time from diagnosis to start of radiotherapy in anal cancer. [PDF]

Colorectal Dis
Hallström J, Johnsson A, Nilsson MP.
europepmc   +1 more source

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Local recurrence or treatment failure? Interpreting the prognostic effect of anal cancer morphology. [PDF]

Colorectal Dis
Canturk AO, Atici SD.
europepmc   +1 more source

Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability

The Journal of Physiology, EarlyView.
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi, Caterina Miro, Annunziata Gaetana Cicatiello, Ilaria Piccialli, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Rosa Sirica, Melania Murolo, Emery Di Cicco, Daniela Terracciano, Anna Pannaccione, Monica Dentice   +12 more
wiley   +1 more source

Rewriting the future of anal cancer care: From disparities to data-driven decisions. [PDF]

ESMO Gastrointest Oncol
Arnold D, Spindler KG.
europepmc   +1 more source