Results 101 to 110 of about 388,819 (310)

Establishment of a novel experimental model of infected anal fistula in rat

open access: yesLaboratory Animal Research, 2022
Refractory Crohn's-like enterocutaneous fistula indicates the aggressive manifestation and lead to poor prognosis of patients. The development of multidisciplinary strategies for fistula administration largely subjects to the deficiency of animal model ...
Meng Zhao   +3 more
doaj   +1 more source

Perioperative utilization of JAK inhibitors in Perianal Fistulizing Crohn's disease

open access: yesJPGN Reports, EarlyView.
Abstract With the recent approval of small molecule drugs such as upadacitinib in adult inflammatory bowel disease (IBD), their utilization is becoming more common; however, there is limited data on perioperative risks or optimal timing of cessation and resumption to mitigate flares. Current recommendations suggest holding these medications for 14 days
Alexander Lyons   +2 more
wiley   +1 more source

Advances in the application of video-assisted anal fistula treatment technology in complex anal fistulas

open access: yes结直肠肛门外科
Complex anal fistula is a common disease in colorectal surgery and is mainly treated surgically. Due to factors such as the high location of the lesion, the curvature of the fistula tract and the presence of dead space, recurrence and postoperative ...
Abduq Youmujiang Abduq Limu, Lu Ming
doaj   +1 more source

Isolated anal tuberculosis presenting as an anal fistula in an immunocompetent child

open access: yesJPGN Reports, EarlyView.
Abstract Extra‐pulmonary tuberculosis accounts for less than 15% of all tuberculosis cases, while intestinal tuberculosis accounts for less than 1% of extra‐pulmonary forms of the disease. Abdominal organ involvement is more common, but extension to the ano‐perineal region is extremely rare.
Mariam Lagrine   +4 more
wiley   +1 more source

Washed Microbiota Transplantation Using Ileocolic Transendoscopic Enteral Tubing Versus Basic Treatments for Intestinal Inflammatory Obstruction in Crohn's Disease: A Multicenter Concurrent Controlled Trial

open access: yesMicrobiota Medicine Research, EarlyView.
Washed microbiota transplantation using ileocolic transendoscopic enteral tubing was identified as a viable, effective and safe bridge treatment for intestinal inflammatory obstruction in Crohn's disease, demonstrating significantly higher 28‐day improvement rates compared to basic treatment.
You Yu   +11 more
wiley   +1 more source

A Multicenter Randomized Controlled Trial Comparing Safety, Efficacy, and Cost-effectiveness of the Surgisis Anal Fistula Plug Versus Surgeon's Preference for Transsphincteric Fistula-in-Ano

open access: yesAnnals of Surgery, 2020
Supplemental Digital Content is available in the text Objective: To undertake a randomized comparison of the Biodesign Surgisis anal fistula plug against surgeon's preference in treating cryptoglandular transsphincteric fistula-in-ano. Summary Background
D. Jayne   +10 more
semanticscholar   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa   +7 more
wiley   +1 more source

Evidence Suggests Prophylactic Antibiotics May Be Unnecessary in Anorectal Surgery—A Systematic Review and Meta‐Analysis

open access: yesWorld Journal of Surgery, EarlyView.
Current evidence does not support the routine use of prophylactic antibiotics in uncomplicated anorectal procedures. However, the certainty of evidence is limited by small sample sizes, methodological heterogeneity, and limited number of available studies. Large‐scale randomized trials are required to strengthen this evidence base.
James Jin   +3 more
wiley   +1 more source

Malignancy within a tail gut cyst:a case of retrorectal carcinoid tumour [PDF]

open access: yes, 2014
Purpose. Tailgut cysts with malignant transformation are rare entities. We discuss the diagnostic strategy and treatment of a malignancy within a tailgut cyst. Methods.
Abukar, A. A.   +7 more
core   +7 more sources

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