Results 151 to 160 of about 118,646 (279)

A comparison between subpleural patient-controlled analgesia by bupivacaine and intermittent analgesia in post-operative thoracotomy: A double-blind randomized clinical trial

Journal of Research in Medical Sciences, 2011
Background: The efficacy of subpleural analgesia to reduce postoperative pain intensity in patients after lateral thoracotomy is controversial. In this study, we demonstrated the efficacy of two types of subpleural analgesia.
Vahid Goharian, Sayyed Abbas Tabatabaee, Sayyed MozafarHashemi, Gholamreza Mohajery, Mohammad Arash Ramezani, Fatemeh Shabani, Zahra MotevalliEmami   +6 more
doaj  

Unveiling Hepatic Protein Alterations in Neonatal and Infant Biliary Atresia

Clinical Pharmacology &Therapeutics, EarlyView.
Pediatric populations differ from adults in drug elimination capacity. While current scaling methods account for enzyme and transporter maturation, they overlook comorbidities, such as biliary atresia (BA), a liver disease appearing within the first 2–8 weeks of life that can progress to cirrhosis.
Zubida M. Al‐Majdoub, Martyn Howard, Brahim Achour, Jill Barber, Naved Alizai, Amin Rostami‐Hodjegan   +5 more
wiley   +1 more source

Patient‐ and Clinician‐Related Factors Associated With the Reduction in Opioid Use Among Adults With Chronic Non‐Cancer Pain: A Systematic Review

Clinical Pharmacology &Therapeutics, EarlyView.
Despite known risks, opioids are widely used for chronic non‐cancer pain (CNCP). Clinical guidelines now recommend deprescribing, but factors predicting success are poorly understood. This systematic review aimed to identify clinician and patient factors associated with attaining successful opioid dose reduction or discontinuation in adults with CNCP ...
Alessandra C. Marcelo, Sarah N. Hilmer, David J. Hunter, Stephanie Mathieson, Riyaas Mohamed, Leo Li, Natalie Fung, Anthony Yue, Manuela L. Ferreira   +8 more
wiley   +1 more source

Effect of Intrathecal Hydromorphone on the Duration and Efficacy of Postoperative Analgesia in Patients Undergoing Benign Anorectal Surgery: Protocol for a Randomized, Double-Blind, Controlled Trial. [PDF]

J Pain Res
Cao Y, Zhou Y, Zhou D, Xiong C, Fu L, Chen X, Zhang X.   +6 more
europepmc   +1 more source

Anesthesia Case of the Month [PDF]

, 2016
Garcia De Carellan, A, Lam, R W, Viscasillas, J   +2 more
core   +2 more sources

Spotlight commentary: Deprescribing in long‐term care facilities—Towards safer and smarter medication use in older adults

British Journal of Clinical Pharmacology, EarlyView.
Nataša Skočibušić, Igor Rubinić, Vera Vlahović‐Palčevski   +2 more
wiley   +1 more source

Evaluation of Therapeutic Opioids in Skin‐Derived Matrices (Sweat and Sebum) of Neonatal and Pediatric Patients and Their Role in Opioid Incorporation Into Hair

Drug Testing and Analysis, EarlyView.
Concentration ranges, dose–concentration relationships, and metabolite‐to‐parent drug ratios of therapeutic opioids were evaluated in hair and skin swab samples of 150 pediatric patients. Skin‐derived matrices such as sweat or sebum were shown to contribute to analyte incorporation into hair in a systematic manner.
Max Polke, Florian Zapf, Julia T. Scherer, Clarissa D. Voegel, Tanja Restin, Marc W. Schmid, Thomas Kraemer, Tina M. Binz   +7 more
wiley   +1 more source

Patient-Controlled Analgesia in ICU: A Scoping Review. [PDF]

J Pers Med
Califano A, Caldonazzo R, Gotti M, Sabbatini G, Galimberti A, Angelo P, Formenti P.   +6 more
europepmc   +1 more source

NICEly does it: economic analysis within evidence-based clinical practice guidelines [PDF]

There is increasing professional and policy interest in the role of clinical guidelines for promoting effective and efficient health care. The NHS Health Technology Assessment Programme identified an urgent need, when such guidelines are produced, to ...
James Mason, Martin Eccles, Mike Drummond, Nick Freemantle   +3 more
core  

Concentration and Detection Time of Nitrous Oxide in Blood Following Controlled Inhalation

Drug Testing and Analysis, EarlyView.
In a study with controlled inhalation of nitrous oxide (N2O), elimination followed a two‐compartment model with half‐lives of 2.4 and 31 min, and N2O remained detectable in blood samples for 1–3 h after inhalation. ABSTRACT Recreational use of nitrous oxide (laughing gas, N2O) is becoming increasingly common and abuse is often seen in relation to ...
Angelica Ørregaard Lindholm, Marie Katrine Klose Nielsen, Mette Kristensen, Mo Haslund Larsen, Johan Heiberg, Brian Schou Rasmussen   +5 more
wiley   +1 more source