Results 171 to 180 of about 77,824 (304)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Patient-Controlled Subcutaneous Analgesia with Hydromorphone versus Oral Oxycontin for Opioid Titration of Cancer Pain: A Prospective Multicenter Randomized Trial

open access: yes
Xiaoguang Xiao,1 Jianhai Sun,2 Dongsheng Zhang,3 Linjun Li,4 Haibo Zhou,5 Yongjun Li,6 Quan Li,7 Zhongshi He,8 Yang Fu,9 Qiwen Duan,10 Guping Zheng,11 Ze Tang,12 Qian Chu,1,* Yuan Chen1,* 1Department of Oncology, Tongji Hospital of Tongji Medical
Chu Q   +13 more
core  

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

open access: yesEpilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden   +5 more
wiley   +1 more source

Unique deficits in place coding across subfields of the hippocampus in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Memory problems are comorbid with temporal lobe epilepsy (TLE). Animal models of TLE reveal impairments in spatial firing fields of hippocampal place cells, providing a potential neural substrate for memory problems. Each subfield of the hippocampus carries out unique aspects of spatial memory, yet little is known about how ...
Brittney L. Boublil   +4 more
wiley   +1 more source

Effect of epileptogenesis on hypercapnic cardioventilatory response in kainic acid rats

open access: yesEpilepsia, EarlyView.
Abstract Objective Cardioventilatory failure is the leading mechanism proposed to underlie sudden unexpected death in epilepsy (SUDEP), which occurs predominantly at night in patients with generalized tonic–clonic seizures. Interictal hypercapnic cardioventilatory responses are suggested to be involved, as they are ablated in chronically epileptic ...
Auriane Apaire   +7 more
wiley   +1 more source

Comparison of the effects of indomethacin, diclofenac and acetaminophen suppositories on pain score and pethedine usage after cesarean section [PDF]

open access: yes
Background : Cesarean section is one of the common surgeries of women. The rate of cesarean section over the west societies is currently about 14%-15%. In Iran the rate of cesarean section is higher than universal statistics. Acute postoperative pain is
اخوان اکبری, قدرت   +2 more
core  

Opioid-Sparing Multimodal Analgesia versus Standard Analgesia in Hip Fracture Surgery: A Prospective Study. [PDF]

open access: yesJ Orthop Case Rep
Pandoh S   +5 more
europepmc   +1 more source

Modeling temporal lobe epilepsy with hippocampal sclerosis in rats using the selective neurotoxin stable substance P‐saporin

open access: yesEpilepsia, EarlyView.
On day 0 adult male and female rats were injected with Stable Substance P‐Saporin (SSP‐SAP) at 4 unilateral sites along the longitudinal axis of the dentate gyrus. Rats exhibited spontaneous electrographic and behavioral reactive seizures between days 4‐6. There was a progressive loss of CA1 and CA3 neurons and a progressive increase in astrocytes over
Srijal Gupta   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy