Results 81 to 90 of about 410,347 (354)

Ingestion of Amniotic Fluid Enhances\ud Opiate Analgesia in Rats [PDF]

, 1986
Placenta ingestion has recently been shown to enhance opiate-mediated analgesia produced by morphine injection, footshock, or vaginal/cervical stimulation.
Abbott, Patricia, Kristal, Dr. Mark B., Thompson, Alexis C.   +2 more
core  

The Transversus Abdominis Plane Block Provides Effective Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy

, 2008
BACKGROUND: Patients undergoing total abdominal hysterectomy suffer significant postoperative pain. The transversus abdominis plane (TAP) block is a recently described approach to providing analgesia to the anterior abdominal wall.
Ochana, Alan, John G. McDonnell, McDonnell, John G., John G. Laffey, John Carney, Laffey, John G., Bhinder, Raj, Carney, John, Alan Ochana, Raj Bhinder   +9 more
core   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Successful anaesthetic management in a patient scheduled for open-heart surgery for the third time: A case report

Bangabandhu Sheikh Mujib Medical University Journal
Background: Anaesthetic management of patients undergoing third open-heart surgery presents significant challenges due to anatomical distortions, adhesions, and altered haemodynamics.
Mostafa Nuruzzaman, Sanjoy Kumar Saha, Mohammad Musfiqur Rahman, Omar Sadeque Khan, Rezwanul Hoque   +4 more
doaj   +1 more source

Measuring Blood-brain-barrier Permeability Using Evans Blue in Mice

Bio-Protocol, 2015
The blood–brain barrier (BBB) is a highly selective permeability barrier that separates the circulating blood from the brain extracellular fluid in the central nervous system.
Jun-Xia Yang, Yan-Yu Jiang, Yu-Bai Guo
doaj   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

The recent research progress in neurobiological characteristics and pain regulation of the cerebrospinal fluid-contacting nucleus

Anesthesiology and Perioperative Science
The ependymal epithelium forms the cerebrospinal fluid barrier, separating the brain and spinal cord from the cerebrospinal fluid. However, in specific regions of the central nervous system, there are neurons that directly interface with the ...
Jingqiu Wei, He Liu, Fang Zhou, Xianfu Lu, Hongxing Zhang, Licai Zhang   +5 more
doaj   +1 more source

Anesthesia and analgesia in laboratory animals /

, 1997
Anesthesia and Analgesia in Laboratory Animals focuses entirely on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery.
Kohn, Dennis F.
core  

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source