Results 61 to 70 of about 644,703 (404)
The unsolved case of “bone-impairing analgesics”. The endocrine effects of opioids on bone metabolism [PDF]
, 2015 The current literature describes the possible risks for bone fracture in chronic analgesics users. There are three main hypotheses that could explain the increased risk of fracture associated with central analgesics, such as opioids: 1) the increased ...
COLUZZI, FLAMINIA +3 more
core +3 more sources
Pain sensitivity and analgesic use among 10,486 adults: the Tromsø study
BMC Pharmacology and Toxicology, 2017 BackgroundIncreased pain sensitivity is a putative risk factor for chronic pain and consequently for analgesic use. Conversely, analgesic use may be a cause of increased pain sensitivity, e.g., through opioid-induced hyperalgesia.
Per-Jostein Samuelsen +5 more
semanticscholar +1 more source
Long‐Term Opioids in Gout: A Matched Cohort Study From the Veterans Health Administration
Arthritis Care &Research, EarlyView.Objective Though used frequently to treat flare, risk of long‐term opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed long‐term opioids over time.
Lindsay N. Helget +7 more
wiley +1 more source
Experimental pharmacological research regarding some new quinazolin-4-ones derivatives [PDF]
, 2019 A series of new compounds with quinazolin-4-one structure, synthesized by the Pharmaceutical Chemistry Department of the Faculty of Pharmacy of the University of Medicine and Pharmacy “Carol Davila” Bucharest, was studied.
Bratu, Mihaela +8 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart +14 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2007 Rheedia longifolia Planch et Triana belongs to the Clusiaceae family. This plant is widely distributed in Brazil, but its chemical and pharmacological properties have not yet been studied. We report here that leaves aqueous extract of R. longifolia (LAE)
Valber da Silva Frutuoso +9 more
doaj +1 more source
Journal of Contemporary Medicine, 2022 Background: The aim of this study is to evaluate the public's interest in pain and painkillers using Google search activity in countries with the most cases before and during the COVID-19 pandemic (January 2018 - December 2021).
Sevinç Meşe, Seda Gündüz Başçıl
doaj +1 more source
A Study on Ajuga bracteosa wall ex. Benth for analgesic activity [PDF]
, 2011 Ethnopharmacological relevance: Ajuga bracteosa wall ex. Benth (Labiatae) is traditionally used medicine in the treatment of malaria and gout. The plant is substitute of cinchona. Its allied species Ajuga Parviflora is also found sporadically.
Akriti Pal , RS Pawar, Int J Cur Bio Med Sci.
core
Brazilian Journal of Anesthesiology, 2012 Pain treatment involves the usage of common and opioid analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs) and adjuvant analgesics. Traditionally, these drugs are administered systemically or into the neuraxis. However, when analgesics are applied through these pathways, they are associated with significant side effects, which can hinder its use.
Flores, Murilo Pereira +2 more
openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer +5 more
wiley +1 more source