Results 21 to 30 of about 62,166 (293)

Opioid analgesics, stigma, shame and identity [PDF]

open access: yes, 2021
This chapter explores how the lives of individuals affected by the consumption of opioid analgesics for pain relief have often only been framed as clinical or public health concerns and have neglected important additional psychosocial consequences and in
Cooper, R.J., Richard J. Cooper
core   +1 more source

Recent Chemical and Pharmacological Developments on 14-Oxygenated-N-methylmorphinan-6-ones

open access: yesMolecules, 2021
Adequate pain management, particularly chronic pain, remains a major challenge associated with modern-day medicine. Current pharmacotherapy offers unsatisfactory long-term solutions due to serious side effects related to the chronic administration of ...
Mariana Spetea, Helmut Schmidhammer
doaj   +1 more source

The Effect of Postoperative Pain Treatment on the Incidence of Anastomotic Insufficiency after Rectal and Rectosigmoideal Surgery

open access: yesPrague Medical Report, 2013
The aim of prospective study was to evaluate the pain relief in the postoperative period and consumption of opioid and non-opioid analgesics as a risk factor of the anastomotic insufficiency after rectal and rectosigmoideal resection for carcinoma ...
S. Adámek   +5 more
doaj   +1 more source

Gamma‐aminobutyric acid transaminase genetic polymorphism is a candidate locus for responsiveness to opioid analgesics in patients with cancer pain: An exploratory study

open access: yesNeuropsychopharmacology Reports, 2018
Aim Cancer pain impairs not only physical functions but also social functions and roles. Consequently, the overall health‐related quality of life of patients with cancer pain deteriorates. Opioid analgesics are recommended for treating moderate to strong
Yaeko Yokoshima   +11 more
doaj   +1 more source

Novel Synthetic Opioids (NSO) Use in Opioid Dependents Entering Detoxification Treatment

open access: yesFrontiers in Psychiatry, 2022
IntroductionOver the last decade, the use of New/Novel Synthetic Opioids (NSO) has emerged as an increasing problem, and especially so in the USA. However, only little is known about the prevalence and history of NSO use in European heroin dependents ...
Michael Specka   +13 more
doaj   +1 more source

Safety of opioid patch initiation in Australian residential aged care [PDF]

open access: yes, 2015
Explores opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Abstract Objective: To explore opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Design:
Lisa Pont   +5 more
core   +1 more source

Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]

open access: yes, 2015
Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Pilgrim, Jennifer   +20 more
core   +1 more source

The effect of opioid analgesics, benzodiazepines, gabapentinoids, and opioid agonist treatment on mortality risk among opioid-dependent people.

open access: yesInternational Journal of Population Data Science, 2022
Background As dispensings for benzodiazepines and gabapentinoids have increased in recent years, risk of increased mortality has been identified, particularly when used with opioids. There is limited research examining use of these medicines among people
Chrianna Bharat   +6 more
doaj   +1 more source

Opioid peptide-derived analgesics [PDF]

open access: yesThe AAPS Journal, 2005
Two recent developments of opioid peptide-based analgesics are reviewed. The first part of the review discusses the dermorphin-derived, cationic-aromatic tetrapeptide H-Dmt-D-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA, where Dmt indicates 2',6'-dimethyltyrosine), which showed subnanomolar mu receptor binding affinity, extraordinary mu receptor selectivity, and ...
openaire   +2 more sources

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