Results 41 to 50 of about 194,876 (191)

Non-opioid analgesics in contemporary treatment of pain [PDF]

, 2018
Pain is a symptom of most diseases that can significantly impair the patient's quality of life. In many diseases it is impossible to eliminate the cause of pain therefore the real goal of treatment is the removal of pain as a symptom, by application of ...
Micov Ana, Pecikoza Uroš, Tomić Maja
core   +2 more sources

TREATMENT OF PAIN IN PEDIATRIC PATIENTS [PDF]

Journal of IMAB, 2016
The article clarifies that pain is a multidimensional phenomenon both in adults and children. The authors reviewed the literature and surveyed the clinical data on the management of pain in pediatric patients. The conclusion was made that pain management
Nikolay Yanev, Mila Vlaskovska
doaj   +1 more source

Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects

Nature Communications, 2019
Tolerance and other side effects are important limitations to the use of opioids as analgesics. In this study, the authors generated mice lacking phosphorylation sites on the µ-opioid receptor to assess their contribution to the analgesic, tolerance and ...
A. Kliewer, F. Schmiedel, S. Sianati, A. Bailey, J. T. Bateman, E. S. Levitt, J. T. Williams, M. J. Christie, S. Schulz   +8 more
doaj   +1 more source

Meta-analysis for the cumulative amount of opioid analgesics used.

, 2016
Meta-analysis for the cumulative amount of opioid analgesics used.
I-Fan Chen (2558716), Jaung-Geng Lin (172324), Pei-Chuan Tzeng (2558722), Mei-Ling Yeh (2558719), Fei-Peng Lee (2558713), Chiehfeng Chen (2558707), Ming-Shun Wu (588109), Kee-Hsin Chen (2558710), Shihping Kevin Huang (2558704)   +8 more
core   +1 more source

Mental disorder prevalence in chronic pain patients using opioid versus non‐opioid analgesics: A registry‐linkage study [PDF]

, 2023
Background Chronic pain and mental disorders are leading causes of disability worldwide. Individuals with chronic pain are more likely to experience mental disorders compared to individuals without chronic pain, but large-scale estimates are lacking.
Nesvåg, R., I. Odsbu, M. Handal, T. G. Lid, Lid, T. G., R. Nesvåg, Odsbu, I., Hamina, A., S. Skurtveit, Gjerde, L. C., Skurtveit, S., Borchgrevink, P. C., Clausen, T., T. Clausen, Handal, M., L. C. Gjerde, A. Hamina, P. C. Borchgrevink   +17 more
core   +1 more source

National opioid pharmacotherapy statistics 2014 [PDF]

, 2015
Summary Dependence on opioid drugs is associated with a range of health and social problems that affect individual drug users, their family and friends, and the wider public.
Australian Institute of Health and Welfare
core  

How Resistant to Tampering are Codeine Containing Analgesics on the Market? Assessing the Potential for Opioid Extraction [PDF]

, 2016
Introduction: Misuse of opioid analgesics, in combination with diversion, dependence, and fatal overdoses, presents a serious problem for public health, which affects many countries worldwide.
Paolo Deluca, Torben Breindahl, Breindahl, Torben; id_orcid, Kimergård, Andreas; id_orcid, Kimergård, Andreas, Hindersson, Peter, Breindahl, Torben, Andreas Kimergård, Deluca, Paolo, Deluca, Paolo; id_orcid, Peter Hindersson   +10 more
core   +1 more source

Combination opioid analgesics

Acute Pain, 2008
Although there is no “ideal analgesic,” scientists and clinicians alike continue to search for compounds with qualities which may approach the “ideal analgesic.” Characteristics of an “ideal” analgesic may include: the agent is a full agonist providing optimal/maximal analgesia for a wide range/variety of pain states (e.g., broad spectrum analgesic ...
openaire   +2 more sources

Opioid analgesics for chronic noncancer pain in patients prescribed opioid agonist therapy or with opioid use disorder: A systematic review

Canadian Journal of Pain
Background Opioid use disorder (OUD) is a growing public health concern in North America, often coexisting with chronic noncancer pain (CNCP). Managing both conditions presents unique challenges, highlighting the need for evidence to guide decision ...
Vahid Ashoorion, Tushar Sood, Shezel Muneer, Jason W. Busse, Danielle Rice, Jaris Swidrovich, Umair Majid, James Abesteh, Randi Q. Mao, Abhimanyu Sud   +9 more
doaj   +1 more source

Management of pain treatment in the early postoperative period. Practice of using ketorolac. A clinical case

Медицина болю, 2020
The current strategy of rational perioperative analgesia involves reducing the use of opioid analgesics and preventing associated side effects. Today it is known that the use of opioid analgesics can further lead to the development of hyperalgesia ...
Dmytro Dmytriiev, A Andriiets, E Andriiets, V Bankivsky, S Yatsenko   +4 more
doaj   +1 more source