Results 81 to 90 of about 62,305 (293)

Micro‐QuEChERS Extraction for Broad‐Spectrum LC‐QQQ‐MS Quantification of Nitazene Analogs in Plasma: A Validated Method With Casework Application

open access: yesDrug Testing and Analysis, EarlyView.
Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza   +7 more
wiley   +1 more source

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee   +4 more
wiley   +1 more source

Prevalence of prescription opioid analgesic use among adults : United States, 2013\u20132016 [PDF]

open access: yes
Prescription opioid analgesics are used to treat pain resulting from a variety of health conditions, surgery, and injury. However, opioid-related deaths have emerged as a public health issue (1), and efforts to monitor prescription opioid analgesic use ...

core  

Fatalities within seven days after equine standing sedation: A prospective, multicentre study

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla   +6 more
wiley   +1 more source

Research progress on biased μ-opioid receptor agonists

open access: yes徐州医科大学学报
Opioid analgesics, which primarily exert their effects through μ-opioid receptors, have long been valuable choices in pain management. However, opioid analgesics often cause various adverse reactions that are common to traditional opioids, especially ...
LI Ning, LIU Cunming
doaj   +1 more source

Multimodal Pain Management in Older Elective Arthroplasty Patients

open access: yesGeriatric Orthopaedic Surgery & Rehabilitation, 2017
Background: Pain management after elective arthroplasty in older adults is complicated due to the risk of undertreatment of postoperative pain and potential adverse effects from analgesics, notably opioids.
Elaine Brooks MN   +3 more
doaj   +1 more source

Observations of the Opioid Workgroup of the Board of Scientific Counselors of the National Center for Injury Prevention and Control on the updated CDC Guideline for prescribing opioids [PDF]

open access: yes
Observations on CDC Guideline for Prescribing Opioids \u2013 United States, 2022This document outlines the observations of the Opioid Workgroup on the updated CDC Guideline for Prescribing Opioids.

core  

Cheek tooth extraction in geriatric versus non‐geriatric horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Age‐related dental changes are major contributors to dental disorders in older horses, and cheek tooth extractions are often required to maintain masticatory function and oral comfort. However, limited information is available on clinical and treatment characteristics in this older patient population.
Elias Mair   +4 more
wiley   +1 more source

Opioid analgesics: Managing the predictable

open access: yesClinical Medicine
It is imperative for clinicians to understand the common adverse effects of opioid therapy and ensure patients are properly counselled on them prior to opioid initiation. Predictable adverse effects are wide ranging, and include bowel dysfunction, nausea,
A Barnes   +2 more
doaj   +1 more source

Opioid analgesics for rheumatoid arthritis pain [PDF]

open access: yes, 2013
Clinical Question: Do the benefits of opioid analgesics outweigh the risks in patients with persistent pain due to rheumatoid arthritis? Bottom Line: Weak opioids (such as codeine, dextropropoxyphene, and tramadol) may be effective in the short-term ...
Richards, B.   +5 more
core   +1 more source

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