Results 141 to 150 of about 52,277 (300)

Codeine and Metabolite Concentrations in the Breastfed Neonate

Pediatric Anesthesia, EarlyView.
ABSTRACT Analgesic effect from codeine is from its metabolite, morphine. Morphine is formed by the O‐demethylation of codeine and that enzyme is controlled by the cytochrome P450 2D6. More than 60 alleles in the CYP2D6 gene have been identified. This spectrum of polymorphism can be categorized into four groups: poor (PM), intermediate (IM), normal (NM),
Brian J. Anderson, Jacqueline A. Hannam
wiley   +1 more source

Differences in the prescription of analgesics in the treatment of cancer pain in six Danish pain treatment units

, 2007
30-40% of cancer patients suffer from pain at diagnosis while 70-80% of patients at progressed stages of the disease suffer from pain. Background pain is treated with long-acting opioids.
Jonsson, Torsten, Sjøgren, Per, Hansen, Ole Bo, Sonne, Nan Margrethe, Christrup, Lona L, Olesen, Anne Estrup, Højsted, Jette, Jarvig, Line, Jensen, Niels-Henrik, Sørensen, Jacob Thorsted   +9 more
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Effect of Intraoperative Regional Anesthesia on Postoperative Outcomes in Pediatric Cardiac Surgery—A Systematic Review of Randomized Controlled Trials

Pediatric Anesthesia, EarlyView.
ABSTRACT Objective To conduct a meta‐analysis of postoperative outcomes following the use of regional anesthesia in pediatric cardiac surgery. Data Sources We searched PubMed (MEDLINE), Web of Science, CINAHL, CENTRAL, and Scopus in December 2024 (PROSPERO: CRD420025635423; registered January 2025).
Katariina Hiisivuori, Heli Salmi, Vesa K. Kontinen, Ilari Kuitunen   +3 more
wiley   +1 more source

Teen newsletter : July 2022 \u2013 Opioids

Opioids are a class of drugs used to reduce pain. Opioids include the illegal drug heroin, synthetic opioids such as fentanyl, and pain medications available legally by prescription. Prescription opioids are generally safe when taken for a short time and

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Multimodal Treatment of Neck Pain in Multiple System Atrophy

Movement Disorders Clinical Practice, EarlyView.
Bianca Caliò, Svenja Schmidt, Alessandra Fanciulli   +2 more
wiley   +1 more source

Plasma Lidocaine Concentrations During Intravenous Lidocaine Infusion Therapy in the Pediatric Population—A Scoping Review

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Intravenous lidocaine therapy (IVLT) is often used in perioperative multimodal analgesia due to its analgesic, anti‐hyperalgesic, and anti‐inflammatory effects. In adults, IVLT doses of 1–2 mg/kg/h produce plasma concentrations of 1–2 μg/mL, within the presumed therapeutic range of 1–5 μg/mL.
McKenna Postles, Amanda Barton, Nicholas West, Gillian Lauder   +3 more
wiley   +1 more source

Trends in opioids prescribed at discharge from emergency departments among adults : United States, 2006\u20132017 [PDF]

Objective\u2014This report describes trends in opioid prescribing at emergency department (ED) discharge among adults from 2006\u20132007 through 2016\u20132017, by selected patient and hospital characteristics and the type of opioids prescribed.Methods ...

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Processed EEG Monitoring During Pediatric Procedural Sedation: Correlation Between the Narcotrend Index and the Pediatric Sedation State Scale

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Objective assessment of sedation depth in children undergoing procedural sedation while maintaining spontaneous breathing and protective reflexes can be challenging. Processed electroencephalogram (pEEG) monitoring systems such as the Narcotrend monitor may provide continuous information regarding the depth of sedation.
Hendryk Schneider, Daniel Matheisl, Martin Kuntz, Hans Fuchs   +3 more
wiley   +1 more source

Association of Preoperative Inflammatory Markers With Preoperative Anxiety and Emergence Agitation in Children

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Emergence agitation (EA) is a postoperative neurobehavioral complication characterized by a transient disturbance in cognition and perception following anesthesia. Neuroinflammation is thought to play a central role in its pathophysiology.
Nezahat Merve Ata Soylu, Zehra Hatipoglu, Ersel Gulec, Mediha Turktan, Nurefsan Sadıkoglu, Yusuf Kemal Arslan, Dilek Ozcengiz   +6 more
wiley   +1 more source

Efficacy of opioids versus placebo in chronic pain: a systematic review and meta-analysis of enriched enrollment randomized withdrawal trials

, 2018
Diana S Meske,1 Oluwadolapo D Lawal,1 Harrison Elder,1 Valerie Langberg,2 Florence Paillard,1 Nathaniel Katz1,3 1Analgesic Solutions, Natick, MA, USA, 2The Center for Evidence Synthesis in Health, Brown University, Providence, RI, USA, 3Department of ...
Langberg V, Katz N, Paillard F, Meske DS, Lawal OD, Elder H   +5 more
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