Results 141 to 150 of about 120,626 (262)

Dosing and titrating opioids [PDF]

Evidence indicates that the risk for opioid-use disorder and overdose increases as dosage increases. CDC Guideline for Prescribing Opioids for Chronic Pain provides recommendations about the types of opioid formulations at initiation, starting dosages ...

core  

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Electrical Modalities in the Rehabilitation of Peripheral Nerve Injuries: State of the Literature and Current Clinical Applications

Muscle &Nerve, EarlyView.
ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith, Kirsten M. Schlosser, Ranee Munaim, Stephanie H. Vu, JulieAnn H. Uh, Yusha K. Liu   +5 more
wiley   +1 more source

Differences in the prescription of analgesics in the treatment of cancer pain in six Danish pain treatment units

, 2007
30-40% of cancer patients suffer from pain at diagnosis while 70-80% of patients at progressed stages of the disease suffer from pain. Background pain is treated with long-acting opioids.
Jonsson, Torsten, Sjøgren, Per, Hansen, Ole Bo, Sonne, Nan Margrethe, Christrup, Lona L, Olesen, Anne Estrup, Højsted, Jette, Jarvig, Line, Jensen, Niels-Henrik, Sørensen, Jacob Thorsted   +9 more
core   +1 more source

Malnutrition in cancer surgery: A retrospective study on screening practices and outcomes

Nutrition in Clinical Practice, EarlyView.
Abstract Background Preoperative nutrition risk screening and referral for optimization are recommended for patients undergoing cancer surgery; however, despite high‐risk individuals being identified, referral remains variable. This study aimed to determine the prevalence of preoperative undernutrition risk and body mass index (BMI)‐defined ...
Noha Elsherbini, Bhagya Tahasildar, Tarsan Sangarapillai, Vanessa D. Gueorguieva, Sepehr Mehrpouyan, Tawfik Elsherbini, Matei Cotoros, Dong Hyun Kim, Francesco Carli, Chelsia Gillis   +9 more
wiley   +1 more source

Nonpharmacologic Therapy for Pediatric Posttonsillectomy Pain: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To understand efficacies of nonpharmacologic therapy for pediatric posttonsillectomy pain. Data Sources CINAHL, Cochrane Library, PubMed, and Scopus. Review Methods Studies on nonpharmacologic interventions for pediatric posttonsillectomy pain were included in this systematic review.
Justina T. Sargios, David Kayekjian, Shaun A. Nguyen, Pete Peters, Clarice S. Clemmens, William W. Carroll   +5 more
wiley   +1 more source

Early Analgesia for the Management of Acute Pancreatitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Pancreas
Bandyopadhyay S, Khan R, Samajdar SS, Banerjee A.   +3 more
europepmc   +1 more source

Perspectives in Pediatric Ambulatory Anesthesia: Part 1—One Center's 15 Year Evolution in Eligibility, Utilization, Efficiency, and Outcomes

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Ambulatory surgery has become the dominant model of surgical care in the United States as surgical procedures increasingly shifted from inpatient to outpatient sites of practice. Similar growth in volumes has been observed in pediatric practice.
Aaron B. Low, Jennifer L. Chiem, Corrie Casey, Samuel M. Vanderhoek, Lynn D. Martin   +4 more
wiley   +1 more source

Impact of Withdrawal of Extended-Release Morphine 5 mg on Hospital Analgesic Utilization. [PDF]

Basic Clin Pharmacol Toxicol
Eisenhardt MVG, Mejlholm MB, Routhe LG, Olesen AE, Hjelholt AJ.   +4 more
europepmc   +1 more source

Teen newsletter : July 2022 \u2013 Opioids

Opioids are a class of drugs used to reduce pain. Opioids include the illegal drug heroin, synthetic opioids such as fentanyl, and pain medications available legally by prescription. Prescription opioids are generally safe when taken for a short time and

core