Results 181 to 190 of about 283,091 (360)

A Significant Decline in the Number of Newly Dispensed Analgesics During the First COVID-19 Lockdown in The Netherlands. [PDF]

Eur J Pain
Zijlstra MN, Kiani P, Hendriksen PA, Dijkgraaf DM, Garssen J, Verster JC.   +5 more
europepmc   +1 more source

Bioengineered Skin Grafts from Patient‐Derived Decellularized Extracellular Matrix and Autologous Cells for Personalized Regenerative

Advanced Science, EarlyView.
This study presents a patient‐specific skin model using autologous cells, decellularized dermal ECM, and keratin–alginate bioinks. The model supports cell compatibility, collagen deposition, and epidermal differentiation within a biomimetic ECM environment.
RaeHui Kang, Suyeon Shin, Yurim Choi, WonJun Jang, Soojin Park, Mi Kyung Lee, Hyun‐Jong Cho, Yu Shrike Zhang, Han‐Jun Kim, Bo Young Park, Junmin Lee   +10 more
wiley   +1 more source

Pain medication associated with decreased physical performance and rehabilitation progress. [PDF]

Pain Rep
Mendes Fernandes L, Vuistiner P, Burrus C, Konzelmann M, Léger B, Besson M, Luthi F.   +6 more
europepmc   +1 more source

Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis

Advanced Science, EarlyView.
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang, Di Mu, Su Liu, Peng‐Bo Jing, Bin Wu, Xiao‐Mei Yang, Jia‐Yi Ge, Qing‐Yi Li, Hao‐Hao Chen, Feng‐Ming Zhang, Bing Wang, Ying‐Ying Zhang, Linnan Qian, Zi‐Yi Zhu, Yu‐Sen Ou, Shi‐Yu Sun, Lin Luo, Yu Feng, Changyu Jiang, Zhuo Sun, Yong Chen, Hai‐Li Pan, Bin Wang, Fen‐Fei Gao, Jie Wu, Zhigang Lu, Tong Liu, Yan‐Gang Sun, Xing‐Jun Liu   +28 more
wiley   +1 more source

Executive summary of the guideline for prescribing opioid analgesics for chronic non-cancer pain (third edition) by the Japan Society of Pain Clinicians. [PDF]

J Anesth
Kanai A, Iseki M, Iida H, Yamaguchi S, Oiwa A, Yonekura H, Iwashita N, Ueno H, Kimura Y, Takasusuki T, Yamaguchi K, Iida S, Ikemiya H, Oya R, Sugiyama Y, Tanabe K, Taniguchi A, Hattammaru Y, Mizogami M, Yamaguchi S, Yamada K, Fukui S.   +21 more
europepmc   +1 more source

Analgesics

International Journal of Clinical Practice, 1973
openaire   +2 more sources

Targeting Fibrotic Scarring by Mechanoregulation of Il11ra1+/Itga11+ Fibroblast Patterning Promotes Axon Growth after Spinal Cord Injury

Advanced Science, EarlyView.
This study demonstrates that a hydrogel with mechanical properties matching the spinal cord directs fibroblast alignment, reshaping fibrotic scars into parallel matrices. A specific fibroblast subset mediates extracellular matrix remodeling through mechanotransduction, promoting axonal regeneration and neural reconnections, revealing potential ...
Longyou Xiao, Kaixi Shi, Wen Li, Jialin Liu, Pengfei Xie, Zijun Hu, Yu Dai, Haiyan Weng, Qiuju Yuan, Wutian Wu, Limin Rong, Liumin He   +11 more
wiley   +1 more source

Clinical risk factors for unscheduled health care attendance for chronic pain management, and associated treatment costs. [PDF]

Pain Rep
Higgins C, Smith BH, Colvin L.
europepmc   +1 more source

A Modular Chemoenzymatic Cascade Simplifies Divergent Synthesis of Natural and Unnatural Benzylisoquinoline Alkaloids

Advanced Science, EarlyView.
A simplified chemoenzymatic platform is designed to integrate an enzyme cascade with subsequent chemical steps, enabling the divergent production of diverse benzylisoquinoline alkaloids (BIAs). Demonstrating remarkable versatility and enantioselectivity, four distinct classes of BIAs are efficiently generated, in which the natural medicine papaverine ...
Huiling Liu, Zhenbo Yuan, Yue Gao, Fei Li, Zhiwei Deng, Yan Zhang, Zhengshan Luo, Changmei Liu, Yijian Rao   +8 more
wiley   +1 more source

Topical Analgesics: Pharmacology and Clinical Applications. [PDF]

Anesthesiology
Sisignano M, Rice ASC, Geisslinger G.
europepmc   +1 more source