Results 241 to 250 of about 250,898 (312)

Analgesic use and changes in renal function in patients with heart failure in a real-world setting: a descriptive study using an electronic medical record database. [PDF]

Am Heart J Plus
Ishida R, Takano T, Tokumasu H, Sato N.
europepmc   +1 more source

Effect of Late Second to Early Third Trimester of Pregnancy on the Activity of Renal Organic Anion Transporters (OAT1 and OAT3): A Biomarker Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnant individuals take drugs throughout pregnancy and many of these drugs (e.g., antivirals, antibiotics) are eliminated by renal organic anion transporters (OAT) 1 and OAT3. In vivo studies with OAT1/3 substrate drugs suggest that pregnancy increases renal OAT1/3 activities by 1.5‐ to 1.8‐fold.
Aarzoo Thakur, Jashvant D. Unadkat, Emily E. Fay, Nina Isoherranen, Mary F. Hebert   +4 more
wiley   +1 more source

Perceptions regarding the use of cannabis in orthopaedics for treating musculoskeletal joint pain: A survey of arthritis patients. [PDF]

J Int Med Res
Gjorgjievski M, Madden K, Tushinski D, Adili A, Bullen C, Koziarz F, Koziarz A, de Freitas L, Li S, Bhandari M, Johal H.   +10 more
europepmc   +1 more source

OMIP‐120: A 22‐Marker Spectral Flow Cytometry Panel for the Characterization of Major Immune Populations in Murine Bone Marrow and Osteosarcoma Tissue

Cytometry Part A, EarlyView.
ABSTRACT Tumors that develop in the bone exhibit poor responses to most treatment options, including advanced immunotherapies. Despite its immune‐rich composition, the bone marrow microenvironment often fails to suppress tumor progression and instead promotes tumor growth and immune evasion, although the underlying mechanisms remain poorly understood ...
Simone Foderaro, Manon Mulders, Celine C. E. De Schrijver, Crescenzo Massaro, Alberta G. A. Paul, Juan J. Garcia‐Vallejo, Serena Rubina Baglio   +6 more
wiley   +1 more source

Carbamazepine improves perioperative outcomes in patients with tentorial meningiomas. [PDF]

Front Pain Res (Lausanne)
Xu G, Zhu Y, Zhang J, Jiang S, Peng H, Yuan Y.   +5 more
europepmc   +1 more source

Identification and Characterization of the Designer Opioid N‐Pyrrolidino Fluetonitazene in Nasal Spray

Drug Testing and Analysis, EarlyView.
N‐Pyrrolidino fluetonitazene, a synthetic opioid, was identified and characterized in a nasal spray using GC‐MS, LC‐QTOF‐MS, NMR and FT‐IR. ABSTRACT Detection of drugs in non‐biological samples serves as a fundamental basis for identifying emerging trends in the field of new psychoactive substances and provides valuable information for optimizing ...
Fabian Picht, Valentin Cepus, Rona Hohlfeld, Julian Klingbeil, Marco Weber   +4 more
wiley   +1 more source

Comparative analysis of pain management protocols in pediatric and adult emergency medicine: a narrative review. [PDF]

Front Public Health
Abdullah I, Khan S, Hashim S, Shakeel F, Amro M, Sheikh Saleh D, Hassan FE.   +6 more
europepmc   +1 more source

Segmental Hair Analysis of Diphenhydramine and Cyclizine Following a Single Dose

Drug Testing and Analysis, EarlyView.
A single oral dose of diphenhydramine and cyclizine can be quantified in human head hair for a minimum of 5 months and, in certain cases, for up to 1 year following intake. Among 12 study participants, the measured concentrations ranged from 0 to 610 pg/mg within 1 year post‐intake.
Jan Bílek, Marie Katrine Klose Nielsen, Robert Kronstrand, Sys Stybe Johansen   +3 more
wiley   +1 more source

The role of perioperative tapentadol in inguinal hernia repair: Implications for acute analgesia and chronic postoperative pain - a narrative review. [PDF]

Hernia
Jurdičová M, Fricová J, Masopust V, Rokyta R, Stříteský M, Anders M.   +5 more
europepmc   +1 more source

Investigation of the In Vitro and In Vivo Metabolism and μ‐Opioid Receptor Affinity of the Nitazene N‐Pyrrolidino Fluetonitazene

Drug Testing and Analysis, EarlyView.
Eight metabolites for N‐pyrrolidino fluetonitazene were identified in vitro, three of which (M2, M6 and M8) were present in an authentic urine sample. M2 was the most abundant in vivo metabolite and is a common marker metabolite of nitazepyne‐type substances.
Severin Zemp, Gaia Alluisetti, Wolfgang Weinmann, Bettina Schrag, Frank Sporkert, Maurine Leclerc, Katharina Elisabeth Grafinger   +6 more
wiley   +1 more source