Results 1 to 10 of about 6,598 (209)

Isolation and Characterization of the Wastewater Micropollutant Phenacetin-Degrading Bacterium Rhodococcus sp. Strain PNT-23

Microorganisms, 2023
Phenacetin, an antipyretic and analgesic drug, poses a serious health risk to both humans and aquatic organisms, which is of concern since this micropollutant is frequently detected in various aquatic environments.
Yaxuan Yuan, Kexin Wang, Yihe Liu, Maoting Jiang, Yinhu Jiang, Jiguo Qiu   +5 more
doaj   +2 more sources

Kinetic and Isotherm Studies of the Adsorption Phenacetin onto Two Copper Porous Coordination Compounds: Nonlinear Regression Analysis

Journal of Chemistry, 2022
Two coordination compounds, copper (II) fumarate (CuFum) and copper (II) tartrate (CuTart), synthesized from copper (II) with fumaric acid and tartaric acid as ligands and using the slow evaporation method have been applied to study the adsorption of ...
Djoumbissie Alvine Loris, Tchuifon Tchuifon Donald Raoul, Atemkeng Donlifack Cyrille, Kuete Tiotsop Idris-Hermann, Doungmo Giscard, Tayo Djampouo Alain Clovis, Anagho Solomon Gabche, Ngoune Jean   +7 more
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Case Report: Methemoglobinemia associated with compound aminopyrine-phenacetin tablets supported by toxicological evidence [PDF]

Frontiers in Pharmacology
BackgroundMethemoglobinemia (MetHb) is characterized by the oxidation of ferrous iron (Fe2+) in hemoglobin to the ferric state (Fe3+), resulting in impaired oxygen-carrying capacity and subsequent tissue hypoxia.
Yang Liu, Yang Liu, Xue Zhao, Wenqiang Li, Xupeng Shao, Kailiang Fan, Li Kong, Zekun Wei   +7 more
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Thermodynamic Characteristics of Phenacetin in Solid State and Saturated Solutions in Several Neat and Binary Solvents

Molecules, 2021
The thermodynamic properties of phenacetin in solid state and in saturated conditions in neat and binary solvents were characterized based on differential scanning calorimetry and spectroscopic solubility measurements.
Maciej Przybyłek, Anna Kowalska, Natalia Tymorek, Tomasz Dziaman, Piotr Cysewski   +4 more
doaj   +2 more sources

Physicochemical properties and cytochromes P-450 kinetics of the trifluoroacetamido derivative of phenacetin

Results in Chemistry
Substituting hydrogen atoms with fluorine alters physicochemical properties often resulting in improved drug action relative to the parent molecule. The high electronegativity of fluorine changes the electron density distribution of the molecule; however,
Thomas Shell
exaly   +3 more sources

Discovery of flavonoids as potent inhibitors of CYP1A to alleviate cellular inflammation and oxidative stress induced by benzo[a]pyrene-induced high CYP1A expression [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry
The environmental pollutant benzo[a]pyrene (BaP) can induce cytochrome P450 family 1 subfamily A (CYP1A) or generate metabolic products that disrupt the balance of oxidative stress, triggering inflammatory responses in the lungs and leading to tissue ...
Xiao-Dong Li, Nan-Shan Ma, Ci-Ye He, Li-Wei Zou, Jing Zhang, Zhen-Hua Ni, Yang Ling   +6 more
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Analysis of umbilical cord tissue as an indicator of in utero exposure to toxic adulterating substances

Frontiers in Pediatrics, 2023
In utero drug exposure is a significant public health threat to the well-being and normal development of the neonate. Recently, testing of umbilical cord tissue (UCT) has been employed to measure illicit drug exposure, as drugs used by the mother during ...
Kari M. Midthun, Brandon N. Nelson, Frederick G. Strathmann, Thom Browne, Barry K. Logan, Barry K. Logan   +5 more
doaj   +1 more source

Solubility Characteristics of Acetaminophen and Phenacetin in Binary Mixtures of Aqueous Organic Solvents: Experimental and Deep Machine Learning Screening of Green Dissolution Media

Pharmaceutics, 2022
The solubility of active pharmaceutical ingredients is a mandatory physicochemical characteristic in pharmaceutical practice. However, the number of potential solvents and their mixtures prevents direct measurements of all possible combinations for ...
Piotr Cysewski, Tomasz Jeliński, Maciej Przybyłek, Wiktor Nowak, Michał Olczak   +4 more
doaj   +1 more source

Anti-Tumoral and Anti-Angiogenic Effects of Low-Diluted Phenacetinum on Melanoma

Frontiers in Oncology, 2021
Melanoma is the most aggressive form of skin cancer and the most rapidly expanding cancer in terms of worldwide incidence. If primary cutaneous melanoma is mostly treated with a curative wide local excision, malignant melanoma has a poor prognosis and ...
Camille Fuselier, Sandrine Quemener, Eleonore Dufay, Camille Bour, Camille Boulagnon-Rombi, Camille Boulagnon-Rombi, Nicole Bouland, El-Hadi Djermoune, Jérôme Devy, Laurent Martiny, Christophe Schneider   +10 more
doaj   +1 more source

Potential application of thermo-sensitive hydrogels for controlled release of phenacetin [PDF]

Hemijska Industrija, 2012
Over the past years, many scientific researches have been focused on thermo-sensitive hydrogels containing N-isopropylacrylamide (NIPAM) as a monomer.
Ilić-Stojanović Snežana S., Nikolić Ljubiša B., Nikolić Vesna D., Milić Jela R., Petrović Slobodan D., Kapor Agneš J., Nikolić Goran M.   +6 more
doaj   +1 more source