Results 1 to 10 of about 6,115 (211)

Isolation and Characterization of the Wastewater Micropollutant Phenacetin-Degrading Bacterium Rhodococcus sp. Strain PNT-23 [PDF]

Microorganisms, 2023
Phenacetin, an antipyretic and analgesic drug, poses a serious health risk to both humans and aquatic organisms, which is of concern since this micropollutant is frequently detected in various aquatic environments.
Yaxuan Yuan, Kexin Wang, Yihe Liu, Maoting Jiang, Yinhu Jiang, Jiguo Qiu   +5 more
doaj   +3 more sources

Thermodynamics of dissolution and infrared-spectroscopy of solid dispersions of phenacetin [PDF]

Journal of Advanced Pharmaceutical Technology & Research, 2016
In this work enthalpies of dissolution in water of polyethylene glycols (PEGs) having an average molecular weight of 1000 and 1400, Pluronic-F127, phenacetin as well as the composites prepared from them were measured using solution calorimetry at 298.15 ...
Alexander V Gerasimov, Mikhail A Varfolomeev, Marat A Ziganshin, Valery V Gorbatchuk, Il′naz T Rakipov, Alexander E Klimovitskii, Liana S Usmanova   +6 more
doaj   +3 more sources

Kinetic and Isotherm Studies of the Adsorption Phenacetin onto Two Copper Porous Coordination Compounds: Nonlinear Regression Analysis

Journal of Chemistry, 2022
Two coordination compounds, copper (II) fumarate (CuFum) and copper (II) tartrate (CuTart), synthesized from copper (II) with fumaric acid and tartaric acid as ligands and using the slow evaporation method have been applied to study the adsorption of ...
Djoumbissie Alvine Loris, Tchuifon Tchuifon Donald Raoul, Atemkeng Donlifack Cyrille, Kuete Tiotsop Idris-Hermann, Doungmo Giscard, Tayo Djampouo Alain Clovis, Anagho Solomon Gabche, Ngoune Jean   +7 more
doaj   +2 more sources

The ban on phenacetin is associated with changes in the incidence trends of upper‐urinary tract cancers in Australia

Australian and New Zealand Journal of Public Health, 2014
Background: Phenacetin is an analgesic that causes renal diseases and cancers of the upper‐urinary tract (UUT). It was banned in most countries from the late 1960s.
Sebastien Antoni, Isabelle Soerjomataram, Suzanne Moore, Jacques Ferlay, Freddy Sitas, David P. Smith, David Forman   +6 more
doaj   +3 more sources

Effects of Botrychium ternatum (Thunb) Sw. On Cytochrome P450 Activities in Rats. [PDF]

Pharmacol Res Perspect
Pharmacokinetic effects of Botrychium ternatum (Thunb) Sw. on cytochrome P450 activities. ABSTRACT Drug interactions commonly occur through the activities of cytochrome P450 (CYP). In this study, we evaluated the effects of the Chinese herbal medicine Botrychium Ternatum (Thunb) Sw. (BT) on six CYP enzymes.
Yao J, Hu L, Zhou Q, Al Mamun A, Wang S, Han A.   +5 more
europepmc   +2 more sources

Carcinogenic Medications: A Review of Specific Agents and Molecular Mechanisms of Carcinogenesis. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background Pharmacovigilance has revealed an alarming correlation between certain medications and a higher risk of cancer. In this narrative review, included research from 2020 to 2025, along with a few seminal older studies, so that it provides a clear picture of which drugs actually set off cancer and mechanisms involved at the molecular ...
Seyoum Tadesse D, Tekletsadik K, Begashaw B, Shewasinad Yehualashet A, Mekonnen Ali A, Ayenew KD.   +5 more
europepmc   +2 more sources

Thermodynamic Characteristics of Phenacetin in Solid State and Saturated Solutions in Several Neat and Binary Solvents

Molecules, 2021
The thermodynamic properties of phenacetin in solid state and in saturated conditions in neat and binary solvents were characterized based on differential scanning calorimetry and spectroscopic solubility measurements.
Maciej Przybyłek, Anna Kowalska, Natalia Tymorek, Tomasz Dziaman, Piotr Cysewski   +4 more
doaj   +2 more sources

Analysis of Illicit Street Heroin Seized in Pakistan by Gas Chromatography-Mass Spectrometry (GC-MS) for Identification of Adulterants and Impurities. [PDF]

Int J Anal Chem
Heroin abuse poses a significant public health and law enforcement challenge globally, with concerns in Pakistan due to the prevalence of illicit street heroin and limited data on its composition. This study analyzed 706 heroin samples seized between 2017 and 2022 using gas chromatography–mass spectrometry (GC‐MS) and Fourier transform infrared ...
Usman M, Baig Y, Naseer A, Nardiello D, Quinto M.   +4 more
europepmc   +2 more sources

Modulation of Rat Hepatic CYP1A and 2C Activity by Honokiol and Magnolol: Differential Effects on Phenacetin and Diclofenac Pharmacokinetics In Vivo

Molecules, 2018
Honokiol (2-(4-hydroxy-3-prop-2-enyl-phenyl)-4-prop-2-enyl-phenol) and magnolol (4-Allyl-2-(5-allyl-2-hydroxy-phenyl)phenol) are the major active polyphenol constituents of Magnolia officinalis (Magnoliaceae) bark, which has been widely used in ...
Sang-Bum Kim, Kyu-Sang Kim, Heon-Min Ryu, Seong-Ho Hong, Bo-Kyoung Kim, Dae-Duk Kim, Jin Woo Park, In-Soo Yoon   +7 more
doaj   +2 more sources

Discovery of flavonoids as potent inhibitors of CYP1A to alleviate cellular inflammation and oxidative stress induced by benzo[a]pyrene-induced high CYP1A expression [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry
The environmental pollutant benzo[a]pyrene (BaP) can induce cytochrome P450 family 1 subfamily A (CYP1A) or generate metabolic products that disrupt the balance of oxidative stress, triggering inflammatory responses in the lungs and leading to tissue ...
Xiao-Dong Li, Nan-Shan Ma, Ci-Ye He, Li-Wei Zou, Jing Zhang, Zhen-Hua Ni, Yang Ling   +6 more
doaj   +2 more sources