Results 1 to 10 of about 68,061 (166)
Chemical stability and compatibility of acetaminophen injection with six common opioid drugs: implications for clinical use [PDF]
Brazilian Journal of Medical and Biological ResearchDespite the clinical importance of combining acetaminophen and opioids in multimodal analgesia, their compatibility has not been determined. This study aimed to investigate the stability and feasibility of mixing acetaminophen injection with six commonly
Weilin Huang +6 more
doaj +3 more sources
Journal of education & teaching in emergency medicineThis is a practice structured interview case which is appropriate for emergency medicine residents at all levels of training.Acetaminophen (APAP) is an over-the-counter medication commonly used by adult and pediatric populations. While acetaminophen has demonstrated to be reasonably safe and well-tolerated at therapeutic doses, it can cause severe ...
Schaffer DH, Murray BP, Khazaeni B.
europepmc +3 more sources
Annals of Cardiac Anaesthesia, 2021 Context: Postoperative hyperthermia, which may lead to cognitive decline, is a common complication of cardiovascular surgery with cardiopulmonary bypass (CPB).
Shohei Kaneko +5 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2021 Acetaminophen is a widely used analgesic that has been detected in many water bodies with few reports concerning its potential toxicity to fish. This study sought to assess the developmental, swimming performance and cardiovascular activities of embryo ...
Nosakhare Osazee Erhunmwunse +2 more
doaj +1 more source
Toxicology Communications, 2022 Acetaminophen overdose is a leading cause of liver failure in the United States. Macrophage migration inhibitory factor (MIF) is a cytokine that is released early and promotes acetaminophen toxicity in preclinical models.
Joshua Bloom +3 more
doaj +1 more source
Acetaminophen-induced hypotension in sepsis
Journal of Pharmaceutical Health Care and Sciences, 2022 Background Acetaminophen-induced hypotension has been reported in critically ill patients; however, it remains unclear whether mannitol, present as a stabilizing compound in acetaminophen formulations, affects hemodynamic changes.
Shunsuke Inage +8 more
doaj +1 more source
Delayed Acetaminophen Absorption Resulting in Acute Liver Failure
Case Reports in Critical Care, 2022 Introduction. Acetaminophen is a common medication involved in deliberate and accidental self-poisoning. The acetaminophen treatment nomogram is used to guide acetylcysteine treatment.
Huiling Tan +4 more
doaj +1 more source
Use of Arctium lappa Extract Against Acetaminophen-Induced Hepatotoxicity in Rats
Current Therapeutic Research, 2015 Background: Severe destructive hepatic injuries can be induced by acetaminophen overdose and may lead to acute hepatic failure. Objective: To investigate the ameliorative effects of Arctium lappa root extract on acetaminophen-induced hepatotoxicity ...
Attalla Farag El-Kott, PhD +1 more
doaj +1 more source
Archives of Pharmacy Practice, 2017 Background: Acetaminophen poisoning is becoming an increasingly common social problem in Malaysia. An understanding of consumers' usage pattern of acetaminophen is essential in addressing the issue of accidental acetaminophen poisoning.
Chee Ping Chong +2 more
doaj +1 more source
PLoS ONE, 2015 Metabolomics approaches have enabled the study of new mechanisms of liver injury in experimental models of drug toxicity. Disruption of bile acid homeostasis is a known mechanism of drug induced liver injury.
Laura James +8 more
doaj +1 more source