Results 21 to 30 of about 90,535 (162)

NQO2 is a reactive oxygen species generating off-target for acetaminophen [PDF]

open access: yes, 2014
The analgesic and antipyretic compound acetaminophen (paracetamol) is one of the most used drugs worldwide. Acetaminophen overdose is also the most common cause for acute liver toxicity.
Teemu P. Miettinen   +3 more
core   +1 more source

A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics (The INTERMAP Study) [PDF]

open access: yes, 2012
Information on dietary supplements, medications, and other xenobiotics in epidemiologic surveys is usually obtained from questionnaires and is subject to recall and reporting biases.
Holmes, Elaine   +15 more
core   +1 more source

An evaluation on consumers' usage pattern of acetaminophen (paracetamol): A multicenter study from Penang, Malaysia

open access: yesArchives of Pharmacy Practice, 2017
Background: Acetaminophen poisoning is becoming an increasingly common social problem in Malaysia. An understanding of consumers' usage pattern of acetaminophen is essential in addressing the issue of accidental acetaminophen poisoning.
Chee Ping Chong   +2 more
doaj   +1 more source

Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension

open access: yes, 2022
Spence JD, Grosser T, FitzGerald GA. Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension. Hypertension. 2022;79(9):1922-1926.Acetaminophen is widely regarded as a safe therapy for pain and fever in patients with cardiovascular disease ...
Grosser, Tilo ; https://orcid.org/   +2 more
core   +1 more source

Bananas decrease acetaminophen potency in in vitro assays. [PDF]

open access: yesPLoS ONE, 2018
Edible portions of bananas contain high levels of polyphenol oxidase, which catalyzes reactions in the melanin formation pathway. Tyrosine, a physiological substrate of polyphenol oxidase, has an analogous structure to acetaminophen.
Yoshihiro Uesawa, Naotaka Tsuji
doaj   +1 more source

Effect of Saffron (Crocus sativus L.), as a Bioenhancer, on Pharmacokinetic of Acetaminophen: An Animal Study

open access: yesTraditional and Integrative Medicine, 2023
In Traditional Persian Medicine (TPM) saffron is used as an accompaniment agent “Mobadreq” in poly herbal formulations. According to TPM texts, “Mobadreq” is a substance (or drug) which facilitates access of drugs or food to the whole body or specific ...
Seyede Nargess Sadati Lamardi   +5 more
doaj   +1 more source

False positive acetaminophen concentrations in icteric serum

open access: yesPractical Laboratory Medicine, 2016
Introduction: Serum concentrations of acetaminophen are measured to predict the risk of hepatotoxicity in cases of acetaminophen overdose and to identify acetaminophen use in patients with acute liver injury without a known cause.
L. de Jong   +4 more
doaj   +1 more source

Transaminase and Creatine Kinase Ratios for Differentiating Delayed Acetaminophen Overdose from Rhabdomyolysis

open access: yesWestern Journal of Emergency Medicine, 2018
Introduction: Rhabdomyolysis and delayed acetaminophen hepatotoxicity may be associated with elevated serum transaminase values. Establishing the cause of elevated transaminases may be especially difficult because of limited or inaccurate histories of ...
Joshua B. Radke   +6 more
doaj   +1 more source

Evaluation of intramuscular lateral distribution profile of topically administered acetaminophen in rats [PDF]

open access: yes, 2007
To clarify to what extent topically administered drug molecules horizontally permeate into tissues surrounding the administration site, the intramuscular lateral concentration profile of acetaminophen was investigated in vivo using the ...
A OMOTO   +13 more
core   +1 more source

Acetaminophen overdose associated with double serum concentration peaks [PDF]

open access: yesJournal of Community Hospital Internal Medicine Perspectives, 2015
Acetaminophen is the most commonly used analgesic–antipyretic medication in the United States. Acetaminophen overdose, a frequent cause of drug toxicity, has been recognized as the leading cause of fatal and non-fatal hepatic necrosis.
Cristian Papazoglu   +4 more
doaj   +1 more source

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