Results 11 to 20 of about 82,013 (311)

False positive acetaminophen concentrations in icteric serum

open access: yesPractical Laboratory Medicine, 2016
Introduction: Serum concentrations of acetaminophen are measured to predict the risk of hepatotoxicity in cases of acetaminophen overdose and to identify acetaminophen use in patients with acute liver injury without a known cause.
L. de Jong   +4 more
doaj   +2 more sources

NQO2 is a reactive oxygen species generating off-target for acetaminophen [PDF]

open access: yes, 2014
The analgesic and antipyretic compound acetaminophen (paracetamol) is one of the most used drugs worldwide. Acetaminophen overdose is also the most common cause for acute liver toxicity.
Teemu P. Miettinen   +3 more
core   +1 more source

A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics (The INTERMAP Study) [PDF]

open access: yes, 2012
Information on dietary supplements, medications, and other xenobiotics in epidemiologic surveys is usually obtained from questionnaires and is subject to recall and reporting biases.
Holmes, Elaine   +15 more
core   +1 more source

Possible acetaminophen poisoning complicated by puerperal sepsis

open access: yes, 2021
Acetaminophen (paracetamol) toxicity is an important cause of morbidity and mortality worldwide. It is estimated that poisoning contributes to more than 1 million poisonings and up to half a million deaths each year, yet it is preventable and treatable ...
Kual , Arop M. D., Arop M. D. Kual
core   +1 more source

Bananas decrease acetaminophen potency in in vitro assays. [PDF]

open access: yesPLoS ONE, 2018
Edible portions of bananas contain high levels of polyphenol oxidase, which catalyzes reactions in the melanin formation pathway. Tyrosine, a physiological substrate of polyphenol oxidase, has an analogous structure to acetaminophen.
Yoshihiro Uesawa, Naotaka Tsuji
doaj   +1 more source

Effect of Saffron (Crocus sativus L.), as a Bioenhancer, on Pharmacokinetic of Acetaminophen: An Animal Study

open access: yesTraditional and Integrative Medicine, 2023
In Traditional Persian Medicine (TPM) saffron is used as an accompaniment agent “Mobadreq” in poly herbal formulations. According to TPM texts, “Mobadreq” is a substance (or drug) which facilitates access of drugs or food to the whole body or specific ...
Seyede Nargess Sadati Lamardi   +5 more
doaj   +1 more source

Acetaminophen Hepatotoxicity [PDF]

open access: yesSeminars in Liver Disease, 2019
AbstractAcetaminophen (APAP) is one of the most popular and safe pain medications worldwide. However, due to its wide availability, it is frequently implicated in intentional or unintentional overdoses where it can cause severe liver injury and even acute liver failure (ALF).
Anup, Ramachandran, Hartmut, Jaeschke
openaire   +2 more sources

Transaminase and Creatine Kinase Ratios for Differentiating Delayed Acetaminophen Overdose from Rhabdomyolysis

open access: yesWestern Journal of Emergency Medicine, 2018
Introduction: Rhabdomyolysis and delayed acetaminophen hepatotoxicity may be associated with elevated serum transaminase values. Establishing the cause of elevated transaminases may be especially difficult because of limited or inaccurate histories of ...
Joshua B. Radke   +6 more
doaj   +1 more source

Acetaminophen overdose associated with double serum concentration peaks [PDF]

open access: yesJournal of Community Hospital Internal Medicine Perspectives, 2015
Acetaminophen is the most commonly used analgesic–antipyretic medication in the United States. Acetaminophen overdose, a frequent cause of drug toxicity, has been recognized as the leading cause of fatal and non-fatal hepatic necrosis.
Cristian Papazoglu   +4 more
doaj   +1 more source

Comparison of N-Acetyl Cysteine and Resveratrol Treatments in Acetaminophen Toxicity Model in Rabbits

open access: yesAhi Evran Medical Journal, 2022
Purpose: Acetaminophen is safe analgesic drug but it may cause hepatic failure in high doses. N-acetyl cysteine (NAC) is used in the treatment of acetaminophen intoxication.
Hasan Gazi UYAR   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy