Results 11 to 20 of about 82,013 (311)
False positive acetaminophen concentrations in icteric serum
Introduction: Serum concentrations of acetaminophen are measured to predict the risk of hepatotoxicity in cases of acetaminophen overdose and to identify acetaminophen use in patients with acute liver injury without a known cause.
L. de Jong +4 more
doaj +2 more sources
NQO2 is a reactive oxygen species generating off-target for acetaminophen [PDF]
The analgesic and antipyretic compound acetaminophen (paracetamol) is one of the most used drugs worldwide. Acetaminophen overdose is also the most common cause for acute liver toxicity.
Teemu P. Miettinen +3 more
core +1 more source
A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics (The INTERMAP Study) [PDF]
Information on dietary supplements, medications, and other xenobiotics in epidemiologic surveys is usually obtained from questionnaires and is subject to recall and reporting biases.
Holmes, Elaine +15 more
core +1 more source
Possible acetaminophen poisoning complicated by puerperal sepsis
Acetaminophen (paracetamol) toxicity is an important cause of morbidity and mortality worldwide. It is estimated that poisoning contributes to more than 1 million poisonings and up to half a million deaths each year, yet it is preventable and treatable ...
Kual , Arop M. D., Arop M. D. Kual
core +1 more source
Bananas decrease acetaminophen potency in in vitro assays. [PDF]
Edible portions of bananas contain high levels of polyphenol oxidase, which catalyzes reactions in the melanin formation pathway. Tyrosine, a physiological substrate of polyphenol oxidase, has an analogous structure to acetaminophen.
Yoshihiro Uesawa, Naotaka Tsuji
doaj +1 more source
In Traditional Persian Medicine (TPM) saffron is used as an accompaniment agent “Mobadreq” in poly herbal formulations. According to TPM texts, “Mobadreq” is a substance (or drug) which facilitates access of drugs or food to the whole body or specific ...
Seyede Nargess Sadati Lamardi +5 more
doaj +1 more source
Acetaminophen Hepatotoxicity [PDF]
AbstractAcetaminophen (APAP) is one of the most popular and safe pain medications worldwide. However, due to its wide availability, it is frequently implicated in intentional or unintentional overdoses where it can cause severe liver injury and even acute liver failure (ALF).
Anup, Ramachandran, Hartmut, Jaeschke
openaire +2 more sources
Introduction: Rhabdomyolysis and delayed acetaminophen hepatotoxicity may be associated with elevated serum transaminase values. Establishing the cause of elevated transaminases may be especially difficult because of limited or inaccurate histories of ...
Joshua B. Radke +6 more
doaj +1 more source
Acetaminophen overdose associated with double serum concentration peaks [PDF]
Acetaminophen is the most commonly used analgesic–antipyretic medication in the United States. Acetaminophen overdose, a frequent cause of drug toxicity, has been recognized as the leading cause of fatal and non-fatal hepatic necrosis.
Cristian Papazoglu +4 more
doaj +1 more source
Purpose: Acetaminophen is safe analgesic drug but it may cause hepatic failure in high doses. N-acetyl cysteine (NAC) is used in the treatment of acetaminophen intoxication.
Hasan Gazi UYAR +5 more
doaj +1 more source

