Results 11 to 20 of about 90,535 (162)
PLoS ONE, 2015 Metabolomics approaches have enabled the study of new mechanisms of liver injury in experimental models of drug toxicity. Disruption of bile acid homeostasis is a known mechanism of drug induced liver injury.
Laura James +8 more
doaj +2 more sources
Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease [PDF]
Clinical and Translational Science, 2019 Four complementary approaches were used to investigate acetaminophen overdose as a risk factor for Parkinson's disease (PD). Circulating microRNAs (miRNAs) serum profiles from acetaminophen‐overdosed patients were compared with patients with terminal PD,
Sacha Bohler +7 more
doaj +2 more sources
Use of Arctium lappa Extract Against Acetaminophen-Induced Hepatotoxicity in Rats
Current Therapeutic Research, 2015 Background: Severe destructive hepatic injuries can be induced by acetaminophen overdose and may lead to acute hepatic failure. Objective: To investigate the ameliorative effects of Arctium lappa root extract on acetaminophen-induced hepatotoxicity ...
Attalla Farag El-Kott, PhD +1 more
doaj +2 more sources
Anais da Academia Brasileira de Ciências, 2018 Essential oils of green cumin (Cuminum cyminum) and chamomile (Chamomilla recutita) have antioxidant and anti-inflammatory effects. Acetaminophen, N-acetyl-p-amino-phenol, is an over-the-counter analgesic and antipyretic.
MOHAMED E. EBADA
doaj +3 more sources
Possible acetaminophen poisoning complicated by puerperal sepsis [PDF]
, 2021 Acetaminophen (paracetamol) toxicity is an important cause of morbidity and mortality worldwide. It is estimated that poisoning contributes to more than 1 million poisonings and up to half a million deaths each year, yet it is preventable and treatable ...
Kual , Arop M. D., Arop M. D. Kual
core +1 more source
Annals of Cardiac Anaesthesia, 2021 Context: Postoperative hyperthermia, which may lead to cognitive decline, is a common complication of cardiovascular surgery with cardiopulmonary bypass (CPB).
Shohei Kaneko +5 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2021 Acetaminophen is a widely used analgesic that has been detected in many water bodies with few reports concerning its potential toxicity to fish. This study sought to assess the developmental, swimming performance and cardiovascular activities of embryo ...
Nosakhare Osazee Erhunmwunse +2 more
doaj +1 more source
Toxicology Communications, 2022 Acetaminophen overdose is a leading cause of liver failure in the United States. Macrophage migration inhibitory factor (MIF) is a cytokine that is released early and promotes acetaminophen toxicity in preclinical models.
Joshua Bloom +3 more
doaj +1 more source
Acetaminophen-induced hypotension in sepsis
Journal of Pharmaceutical Health Care and Sciences, 2022 Background Acetaminophen-induced hypotension has been reported in critically ill patients; however, it remains unclear whether mannitol, present as a stabilizing compound in acetaminophen formulations, affects hemodynamic changes.
Shunsuke Inage +8 more
doaj +1 more source
Delayed Acetaminophen Absorption Resulting in Acute Liver Failure
Case Reports in Critical Care, 2022 Introduction. Acetaminophen is a common medication involved in deliberate and accidental self-poisoning. The acetaminophen treatment nomogram is used to guide acetylcysteine treatment.
Huiling Tan +4 more
doaj +1 more source