Results 31 to 40 of about 82,016 (264)

Using a decision tree algorithm to distinguish between repeated supra-therapeutic and acute acetaminophen exposures

open access: yesBMC Medical Informatics and Decision Making, 2023
Background This study aimed to compare clinical and laboratory characteristics of supra-therapeutic (RSTI) and acute acetaminophen exposures using a predictive decision tree (DT) algorithm.
Omid Mehrpour   +4 more
doaj   +1 more source

Acetaminophen metabolism by the perfused rat liver twelve hours after acetaminophen overdose [PDF]

open access: yes, 1985
The effect of a toxic dose of acetaminophen on the hepatic conjugations of acetaminophen was studied in single pass perfused livers from rats given acetaminophen overdose 12 hr prior to perfusion and from control rats.
Skovgaard, Lene T.   +2 more
core   +1 more source

Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease

open access: yesClinical and Translational Science, 2019
Four complementary approaches were used to investigate acetaminophen overdose as a risk factor for Parkinson's disease (PD). Circulating microRNAs (miRNAs) serum profiles from acetaminophen‐overdosed patients were compared with patients with terminal PD,
Sacha Bohler   +7 more
doaj   +1 more source

Association of Prenatal Acetaminophen Exposure Measured in Meconium With Adverse Birth Outcomes in a Canadian Birth Cohort

open access: yesFrontiers in Pediatrics, 2022
BackgroundThe small number of studies examining the association of prenatal acetaminophen with birth outcomes have all relied on maternal self-report.
Brennan H. Baker   +10 more
doaj   +1 more source

Emotions, Music, and Acetaminophen [PDF]

open access: yes, 2021
Music is a complex combination of auditory notes that is made to elicit emotions from the listener. Indeed, when listening to pieces of music, people often like or dislike them as well as feel emotions from them. A recent study (Warrenburg, Huron, & Way,
Bawa, Rani
core  

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer   +4 more
wiley   +1 more source

A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells

open access: yesAngewandte Chemie, EarlyView.
A lipid conjugation strategy anchors a manganese Salen complex within phospholipid membranes, yielding stable, catalytically active liposomes. These lipid–metal assemblies efficiently degrade reactive oxygen species (ROS) and enable intracellular redox control in steatotic HepaRG cells, offering a precise route to biomimetic antioxidant design ...
Olav Vestrheim   +7 more
wiley   +2 more sources

Interaction of Aldehyde dehydrogenase with acetaminophen as examined by spectroscopies and molecular docking

open access: yesBiochemistry and Biophysics Reports, 2017
The interaction of acetaminophen, a non-substrate anionic ligand, with Aldehyde Dehydrogenase was studied by fluorescence, UV–Vis absorption, and circular dichroism spectroscopies under simulated physiological conditions.
Ayodele O. Kolawole
doaj   +1 more source

Public awareness of acetaminophen and risks of drug induced liver injury: Results of a large outpatient clinic survey.

open access: yesPLoS ONE, 2020
Acetaminophen is one of the most commonly consumed analgesics world wide. Generally perceived as a safe medication, it is the most common cause of acute liver failure in the United States with inadvertent hepatotoxicity in half of all cases. We therefore
Robert A Mitchell   +5 more
doaj   +1 more source

Acetaminophen Use Concomitant with Long-Lasting Flucloxacillin Therapy: A Dangerous Combination

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2020
Acetaminophen and flucloxacillin both interfere with the ?-glutamyl cycle. Long-lasting concomitant use of flucloxacillin and acetaminophen can lead to 5-oxoproline accumulation and severe high anion gap metabolic acidosis.
Luuk René van den Bersselaar   +2 more
doaj   +1 more source

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