Results 31 to 40 of about 82,013 (311)

A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells

open access: yesAngewandte Chemie, EarlyView.
A lipid conjugation strategy anchors a manganese Salen complex within phospholipid membranes, yielding stable, catalytically active liposomes. These lipid–metal assemblies efficiently degrade reactive oxygen species (ROS) and enable intracellular redox control in steatotic HepaRG cells, offering a precise route to biomimetic antioxidant design ...
Olav Vestrheim   +7 more
wiley   +2 more sources

Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease

open access: yesClinical and Translational Science, 2019
Four complementary approaches were used to investigate acetaminophen overdose as a risk factor for Parkinson's disease (PD). Circulating microRNAs (miRNAs) serum profiles from acetaminophen‐overdosed patients were compared with patients with terminal PD,
Sacha Bohler   +7 more
doaj   +1 more source

Association of Prenatal Acetaminophen Exposure Measured in Meconium With Adverse Birth Outcomes in a Canadian Birth Cohort

open access: yesFrontiers in Pediatrics, 2022
BackgroundThe small number of studies examining the association of prenatal acetaminophen with birth outcomes have all relied on maternal self-report.
Brennan H. Baker   +10 more
doaj   +1 more source

Evaluation of intramuscular lateral distribution profile of topically administered acetaminophen in rats

open access: yes, 2007
To clarify to what extent topically administered drug molecules horizontally permeate into tissues surrounding the administration site, the intramuscular lateral concentration profile of acetaminophen was investigated in vivo using the ...
A OMOTO   +13 more
core   +1 more source

Emotions, Music, and Acetaminophen [PDF]

open access: yes, 2021
Music is a complex combination of auditory notes that is made to elicit emotions from the listener. Indeed, when listening to pieces of music, people often like or dislike them as well as feel emotions from them. A recent study (Warrenburg, Huron, & Way,
Bawa, Rani
core  

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Interaction of Aldehyde dehydrogenase with acetaminophen as examined by spectroscopies and molecular docking

open access: yesBiochemistry and Biophysics Reports, 2017
The interaction of acetaminophen, a non-substrate anionic ligand, with Aldehyde Dehydrogenase was studied by fluorescence, UV–Vis absorption, and circular dichroism spectroscopies under simulated physiological conditions.
Ayodele O. Kolawole
doaj   +1 more source

Public awareness of acetaminophen and risks of drug induced liver injury: Results of a large outpatient clinic survey.

open access: yesPLoS ONE, 2020
Acetaminophen is one of the most commonly consumed analgesics world wide. Generally perceived as a safe medication, it is the most common cause of acute liver failure in the United States with inadvertent hepatotoxicity in half of all cases. We therefore
Robert A Mitchell   +5 more
doaj   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer   +4 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

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