Results 1 to 10 of about 58,096 (266)
Interrupted time-series analysis of regulations to reduce paracetamol (acetaminophen) poisoning.
BackgroundParacetamol (acetaminophen) poisoning is the leading cause of acute liver failure in Great Britain and the United States. Successful interventions to reduced harm from paracetamol poisoning are needed.
Oliver W Morgan +2 more
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Role of amifostine in preventing liver injury caused by paracetamol intoxication
This investigation attempted to examine the possible protective impact of amifostine, alone or in combination with N-acetylcysteine (NAC), in paracetamol-induced liver injury.
Fatih Turkmen +8 more
doaj +1 more source
Investigation of the effect of paracetamol against glutamate-induced cytotoxicity in C6 glia cells
Paracetamol is an active metabolite with analgesic and antipyretic properties of phenacetin, which is sold without a prescription in our country and in many countries.
Kenan Yıldızhan, Murat Doğan
doaj
Background In the practice of postoperative pain management, pain is still poorly managed in low resource setting where the practice of epidural and opioid free analgesia is impractical.
Zemedu Aweke +3 more
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Paracetamol use in pregnancy: Not as safe as we may think?
Paracetamol is used by more than 50% of women worldwide during pregnancy; headache representing the most frequent indication. Several studies report that long‐term exposure to paracetamol in utero is associated with adverse neurodevelopmental outcomes in
Katinka Nilsen +2 more
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Paracetamol cardiotoxicity [PDF]
Summary A 29 year old man with a significant paracetamol overdose was found to have an abnormal electrocardiograph which, in the absence of hepatic encephalopathy, was considered due to a direct cardiotoxic effect of the drug. A functional coronary insufficiency resulting from inhibition of endothelium-derived relaxing factor secondary ...
A, Armour, S D, Slater
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Hepatoprotective effect of punica granatum seed oil extract on paracetamol intoxication in rat via inhibory effect of cyp2e1 [PDF]
Punica granatum seed oil enriched by punikalagins has been shown to have a therapeutic effect against antidiabetic, anticancer, antiinflammatory and some organ toxicities. We aimed to reveal both protective and therapeutic effects of punica granatum seed
Damla CETIN +3 more
doaj +1 more source
Estimation of paracetamol in urine to assess the diurnal variation
The aim of the present study was to evaluate the diurnal variation of the pharmacokinetics of paracetamol by estimating the urinary free paracetamol level after single oral administration of paracetamol (500 mg) tablet to 24 healthy male volunteers ...
Mithun Chandro Bhowmik +2 more
doaj +1 more source
Background: Strong opioids in the home setting after ambulatory surgery have rarely been studied for fear of hazardous adverse effects such as respiratory depression.
Björn Stessel, MD +6 more
doaj +1 more source
Paracetamol-codeine combinations versus paracetamol alone [PDF]
EDITOR,—In their systematic review Anton J M de Craen and colleagues conclude, on the basis of a range of outcome measures, that the combination of paracetamol and codeine is a more effective analgesic than paracetamol alone.1 They find the increase in efficacy to be small but significant and suggest that future studies should report the proportion of ...
A, Li Wan Po, W Y, Zhang
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