Results 11 to 20 of about 76,985 (314)

Paracetamol: unconventional uses of a well-known drug [PDF]

open access: yes, 2021
Objectives To describe and map what is known about unconventional uses of paracetamol through a scoping review of published literature by adopting adopted a PRISMA systematic approach methodology.
Wazaify, Mayyada   +2 more
core   +1 more source

Egyptian perspectives on potential risk of paracetamol/acetaminophen-induced toxicities: Lessons learnt during COVID-19 pandemic

open access: yesToxicology Reports, 2022
Paracetamol/Acetaminophen was widely used as a first-line antipyretic and analgesic for COVID-19 patients without giving any attention to the potential risk of related toxicities.
Enas M.A. Mostafa   +2 more
doaj   +1 more source

Effects of early life paracetamol use on the incidence of allergic disease and sensitization: 5 year follow-up of an Ethiopian birth cohort. [PDF]

open access: yes, 2014
INTRODUCTION: The hypothesis that paracetamol, one of the most widely used medicines, may increase the risk of asthma and allergic disease is of obvious importance but prospective cohort data looking at dose and timing of exposure are lacking. OBJECTIVE:
Amberbir, Alemayehu   +18 more
core   +1 more source

Multi-omics approach reveals dysregulated genes during hESCs neuronal differentiation exposure to paracetamol

open access: yesiScience, 2023
Summary: Prenatal paracetamol exposure has been associated with neurodevelopmental outcomes in childhood. Pharmacoepigenetic studies show differences in cord blood DNA methylation between unexposed and paracetamol-exposed neonates, however, causality and
Mari Spildrejorde   +11 more
doaj   +1 more source

A New Sensor Based on Graphite Screen Printed Electrode Modified With Cu-Nanocomplex for Determination of Paracetamol [PDF]

open access: yesNanochemistry Research, 2017
Paracetamol is a non-steroidal anti-inflammatory drug used as an antipyretic agent for the alternative to aspirin. Conversely, the overdoses of paracetamol can cause hepatic toxicity and kidney damage.
Hadi Beitollai, Reza Zaimbashi
doaj   +1 more source

Effects of Paracetamol on Vascular Endothelial Growth Factor, Sclerostin and FETUIN-A in the Liver of Rat Fetuses

open access: yesActa Medica Alanya, 2020
Aim: Paracetamol is widely used by important societal groups such as pregnant women and the elderly. Paracetamol, taken in high doses especially during pregnancy, causes liver failure.
Seher Yi̇lmaz   +6 more
doaj   +1 more source

Degradation of paracetamol by catalytic wet air oxidation and sequential adsorption - Catalytic wet air oxidation on activated carbons [PDF]

open access: yes, 2012
The concern about the fate of pharmaceutical products has raised owing to the increasing contamination of rivers, lakes and groundwater. The aim of this paper is to evaluate two different processes for paracetamol removal. The catalytic wet air oxidation
Quesada-Peñate, Isariebel   +5 more
core   +1 more source

Isolation of Novel Bacterial Strains Pseudomonas extremaustralis CSW01 and Stutzerimonas stutzeri CSW02 from Sewage Sludge for Paracetamol Biodegradation

open access: yesMicroorganisms, 2023
Paracetamol is one of the most used pharmaceuticals worldwide, but due to its widespread use it is detected in various environmental matrices, such as surface and ground waters, sediments, soils or even plants, where it is introduced mainly from the ...
Antonio Vargas-Ordóñez   +4 more
doaj   +1 more source

Sonolysis of levodopa and paracetamol in aqueous solutions. [PDF]

open access: yes, 2009
Pharmaceutical products are often present in wastewater treatment effluents, rivers, lakes and, more rarely, in groundwater. The advanced oxidation methods, like ultrasound, find a promising future in the area of wastewater treatment.
Quesada-Peñate, Isariebel   +4 more
core   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

open access: yesHepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli   +13 more
wiley   +1 more source

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