Results 41 to 50 of about 169,592 (332)

Microbial paracetamol degradation involves a high diversity of novel amidase enzyme candidates

open access: yesWater Research X, 2022
Pharmaceuticals are relatively new to nature and often not completely removed in wastewater treatment plants (WWTPs). Consequently, these micropollutants end up in water bodies all around the world posing a great environmental risk. One exception to this
Ana B. Rios-Miguel   +6 more
doaj   +1 more source

Controlled-Release Oxycodone Versus Naproxen at Home After Ambulatory Surgery: A Randomized Controlled Trial

open access: yesCurrent Therapeutic Research, 2014
Background: Strong opioids in the home setting after ambulatory surgery have rarely been studied for fear of hazardous adverse effects such as respiratory depression.
Björn Stessel, MD   +6 more
doaj   +1 more source

The Importance of Hypothermia in the Effects of Paracetamol on the Electrical Activity of the Brain in Pentylenetetrazole Induced Experimental Status Epilepticus in Rats

open access: yesArchives of Epilepsy, 2020
Objectives:Paracetamol is a commonly used analgesic and antipyretic agent. In studies investigating the effects of paracetamol on seizure activity, to our knowledge, the hypothermic effect has not been evaluated in studies investigating the hypothermic ...
Semiha KURT   +5 more
doaj   +1 more source

The Economic Costs of Malaria in Children in three Sub-Saharan Countries: Ghana, Tanzania and Kenya. [PDF]

open access: yes, 2013
Malaria causes significant mortality and morbidity in sub-Saharan Africa (SSA), especially among children less than five years of age (U5 children).
Constenla, Dagna   +4 more
core   +2 more sources

Vat Polymerization 3D Printing for Controlled Drug Release Applications

open access: yesAdvanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari   +2 more
wiley   +1 more source

The association of prior paracetamol intake with outcome of very old intensive care patients with COVID-19: results from an international prospective multicentre trial

open access: yesBMC Geriatrics, 2022
Background In the early COVID-19 pandemic concerns about the correct choice of analgesics in patients with COVID-19 were raised. Little data was available on potential usefulness or harmfulness of prescription free analgesics, such as paracetamol.
Philipp Heinrich Baldia   +26 more
doaj   +1 more source

Developmental changes rather than repeated administration drive paracetamol glucuronidation in neonates and infants [PDF]

open access: yes, 2015
Purpose: Based on recovered metabolite ratios in urine, it has been concluded that paracetamol glucuronidation may be up-regulated upon multiple dosing.
Allegaert, K.M. (Karel)   +6 more
core   +3 more sources

Surface‐Bound Superoxide Radical‐Mediated Photo‐Fenton Mineralization of Ciprofloxacin on Fe‐Sillenite Nanosheets

open access: yesAdvanced Science, EarlyView.
This study systematically compares the degradation efficiency of CIP in a H2O2‐alone system and a novel Bi12FeO20‐H2O2 photo‐Fenton system. It reveals for the first time the presence of a quinone‐imine intermediate in the H2O2‐alone system, which exhibits toxicity comparable to CIP.
Wenting Qiu   +9 more
wiley   +1 more source

A look inside the association codeine-paracetamol: clinical pharmacology supports analgesic efficacy [PDF]

open access: yes, 2015
Acute and chronic pain often requires a multimodal approach. Combination therapy reduces the number of individual daily administrations and improves patient's compliance with the prescribed analgesic treatment. Despite the association codeine/paracetamol
COLUZZI, FLAMINIA, MATTIA, Consalvo
core  

Technoeconomic and sustainability analysis of batch and continuous crystallization for pharmaceutical manufacturing

open access: yesAIChE Journal, EarlyView.
Abstract In pharmaceutical industries, continuous manufacturing methods have already been well established to improve productivity and process intensification. However, to better understand the trade‐offs of continuous crystallizers over the existing batch production systems, a robust technoeconomic cost and sustainability analysis is necessary to ...
Jungsoo Rhim, Zoltan K. Nagy
wiley   +1 more source

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