Results 21 to 30 of about 76,985 (314)
Scientific Reports, 2021 Paracetamol is extensively consumed as an analgesic and antipyretic drug, but at a high dose level, it leads to deleterious side effects, such as hepatic and nephrotoxicity.
Amera Abd El Latif +6 more
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HEPATOPROTECTIVE AND ANTIOXIDANT EFFECT OF FLAVONOID, GOLD AND SILVER NANOPARTICLES AGAINST PARACETAMOL INDUCED LIVER TOXIC IN MALE RATS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut UniversityResearch Design at university of Karbala , 60 adult male rats, aged 9 to 12 weeks and weighing between 190 and 315 grams, were used, divisions to 10 group (G1 The control just received 0.85% saline solution , G2 : 1000 mg of paracetamol and 0.2 mg of Ag ...
Roaa Al-Samak +3 more
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A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells
Angewandte Chemie, EarlyView.A lipid conjugation strategy anchors a manganese Salen complex within phospholipid membranes, yielding stable, catalytically active liposomes. These lipid–metal assemblies efficiently degrade reactive oxygen species (ROS) and enable intracellular redox control in steatotic HepaRG cells, offering a precise route to biomimetic antioxidant design ...
Olav Vestrheim +7 more
wiley +2 more sources
Journal of Applied Sciences and Environmental Management, 2019 The therapeutic activity of date palm extracts (Phoenix dactylifera) against paracetamol-induced hepatotoxicity was studied in rats of the Wistar strain. Forty-eight (48) Wistar rats were assigned into 8 groups equally.
O Ikponmwosa-Eweka, A.I. Eromosele
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Interrupted time-series analysis of regulations to reduce paracetamol (acetaminophen) poisoning.
PLoS Medicine, 2007 BackgroundParacetamol (acetaminophen) poisoning is the leading cause of acute liver failure in Great Britain and the United States. Successful interventions to reduced harm from paracetamol poisoning are needed.
Oliver W Morgan +2 more
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Toxicology Reports, 2022 Paracetamol, also known as acetaminophen (N-acetyl-para-aminophenol, APAP) is the world’s most used over-the-counter analgesic-antipyretic drug. Despite its good safety profile, acetaminophen can cause severe hepatotoxicity in overdose, and poisoning ...
Samuel James Offor +4 more
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Acetaminophen (Paracetamol) [PDF]
Journal of Pain and Symptom Management, 2013 Therapeutic Reviews aim to provide essential independent information for health professionals about drugs used in palliative and hospice care. Additional content is available on www.palliativedrugs.com. Country-specific books (Hospice and Palliative Care Formulary USA, and Palliative Care Formulary, British and Canadian editions) are also available and
Robert, Twycross +3 more
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, 2023 El paracetamol es un contaminante emergente que ha sido identificado en varios cuerpos de agua a nivel mundial, es de origen antropogénico y sus efectos secundarios al ingerir microdosis de este fármaco no han sido reportados, sin embargo, su presencia ...
Salazar Andrade, Francisco David
core +1 more source
BMC Anesthesiology, 2020 Background In the practice of postoperative pain management, pain is still poorly managed in low resource setting where the practice of epidural and opioid free analgesia is impractical.
Zemedu Aweke +3 more
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Paracetamol use in pregnancy: Not as safe as we may think?
Acta Obstetricia et Gynecologica Scandinavica, 2023 Paracetamol is used by more than 50% of women worldwide during pregnancy; headache representing the most frequent indication. Several studies report that long‐term exposure to paracetamol in utero is associated with adverse neurodevelopmental outcomes in
Katinka Nilsen +2 more
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