Results 21 to 30 of about 169,592 (332)

Effects of Paracetamol on Vascular Endothelial Growth Factor, Sclerostin and FETUIN-A in the Liver of Rat Fetuses

Acta Medica Alanya, 2020
Aim: Paracetamol is widely used by important societal groups such as pregnant women and the elderly. Paracetamol, taken in high doses especially during pregnancy, causes liver failure.
Seher Yi̇lmaz, Yeşim Göçmen, Adem Tokpınar, İlyas Uçar, Şükrü Ateş, Seda Avni̇oğlu, Mehtap Ni̇sari̇   +6 more
doaj   +1 more source

Investigating the removal of some pharmaceutical compounds in hospital wastewater treatment plants operating in Saudi Arabia [PDF]

, 2016
The concentrations of 12 pharmaceutical compounds (atenolol, erythromycin, cyclophosphamide, paracetamol, bezafibrate, carbamazepine, ciprofloxacin, caffeine, clarithromycin, lidocaine, sulfamethoxazole and Nacetylsulfamethoxazol (NACS)) were ...
Akunna, Joseph C., Al Qarni, Hamed M., Collier, Phillip, O'Keeffe, Juliette   +3 more
core   +3 more sources

Protective role of Chlorella vulgaris with Thiamine against Paracetamol induced toxic effects on haematological, biochemical, oxidative stress parameters and histopathological changes in Wistar rats

Scientific Reports, 2021
Paracetamol is extensively consumed as an analgesic and antipyretic drug, but at a high dose level, it leads to deleterious side effects, such as hepatic and nephrotoxicity.
Amera Abd El Latif, Doaa H. Assar, Ebtihal M. Elkaw, Hanafy A. Hamza, Dalal Hussien M. Alkhalifah, Wael N. Hozzein, Ragaa A. Hamouda   +6 more
doaj   +1 more source

Sonolysis of levodopa and paracetamol in aqueous solutions. [PDF]

, 2009
Pharmaceutical products are often present in wastewater treatment effluents, rivers, lakes and, more rarely, in groundwater. The advanced oxidation methods, like ultrasound, find a promising future in the area of wastewater treatment.
Delmas, Henri, Julcour-Lebigue, Carine, Jáuregui Haza, Ulises Javier, Quesada-Peñate, Isariebel, Wilhelm, Anne-Marie   +4 more
core   +1 more source

Controlled release from zein matrices: Interplay of drug hydrophobicity and pH [PDF]

, 2015
Purpose: In earlier studies, the corn protein zein is found to be suitable as a sustained release agent, yet the range of drugs for which zein has been studied remains small.
A Katchalsky, AL Sarode, D Xiao, DMR Georget, Erik van der Linden, FA Momany, GW Selling, H Chiue, H Kortejärvi, Jacob Bouman, JW Lawton, M Fujiwara, M Peleg, N Minagawa, NA Peppas, P Argos, P Hurtado-López, Paul Venema, Peter Belton, PL Ritger, PS Belton, Q Jiang, R Paliwal, R Shukla, RA Granberg, Renko de Vries, S Grund, S Podaralla, S Thakral, Sheng Qi, W Huang, X Liu, YH Yong, YK Oh, YK Oh   +34 more
core   +2 more sources

Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) [PDF]

, 2018
The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain Committee is to improve the quality of pain management in children. The ESPA Pain Management Ladder is a clinical practice advisory based upon expert consensus to help to ...
Adamek, Akin, Al-Zaben, Alm, Amminnikutty, Amoli, Anderson, Anderson, Antila, Arcioni, Association of Paediatric Anaesthetists of Great Britain and Ireland, Aubrun, Aveline, Aysenur, Bailey, Bailie, Bakan, Baley, Becke, Beers, Bell, Ben-Meir, Bertini, Bhalla, Birmingham, Bouwmeester, Bozkurt, Breitfeld, Breschan, Breschan, Brown, Brown, Büttner, Carstensen, Cha, Chan, Chou, Conti, Cousins, Crellin, Cyna, Dadure, Dadure, Dahi-Taleghani, Dahmani, Dalens, Das, Derry, Derry, Duedahl, Ecoffey, El-Fattah, Elshammaa, Fendrich, Fieler, Finkel, Flack, Fösel, Ganidagli, Gear, Gemma, Ginsberg, Glover, Habre, He, Hicks, Hinz, Holmer Pettersson, Hong, Howard, Hudcova, Huenseler, Huynh, Höhne, Ingelmo, Ivani, Ivani, Ivani, Ivani, Jahr, Jaksch, José María, Ju, Jöhr, Kamata, Kart, Kimiaei Asadi, Kokki, Kokki, Kokki, Kokki, Koppert, Kost-Byerly, Kost-Byerly, Kubica-Cielińska, Kumar, Kurihara, Kwak, Lam, Laskowski, Lavonas, Leclair, Lee, Leksowski, Leoni, Litalien, Liu, Liu, Lorenzo, Lundeberg, Lönnqvist, Lönnqvist, Lönnqvist, Manworren, Marel, Marhofer, Mazoit, McNicol, Merry, Messerer, Messerer, Miller, Miró, Mobley, Mohammed, Momeni, Moriceau, Morton, Morton, Mukherjee, Müller, Mędrzycka-Dąbrowska, O'Sullivan, Olkkola, Orange, Ousley, Pace, Park, Park, Pasero, Petrat, Pierce, Polaner, Qian, Rabbitts, Redmann, Richer, Rugyte, Sahin, Sammartino, Sandeman, Schnabel, Schnabel, Schug, Schug, Schug, Schultz-Machata, Sekhavat, She, Shirazi, Sng, Soh, Sola, Soulard, Southworth, Sowder, Spacek, Splinter, Stamer, Staschen, Steans, Steffen, Subramanyam, Suresh, Taheri, Tobias, Tsuchiya, Valizadeh, Voepel-Lewis, Walker, Walther-Larsen, Walther-Larsen, Wang, Weintraud, Willschke, Willschke, Willschke, Wilson, Wilson-Smith, Wininger, Wong, Wong, Xue, Xue, Yaster, Yildiz, Yung   +196 more
core   +1 more source

Comparative evaluation of biochemical effects of date palm (Phoenix dactylifera) fruit extracts on paracetamol-induced hepatotoxicity in Wistar rats

Journal of Applied Sciences and Environmental Management, 2019
The therapeutic activity of date palm extracts (Phoenix dactylifera) against paracetamol-induced hepatotoxicity was studied in rats of the Wistar strain. Forty-eight (48) Wistar rats were assigned into 8 groups equally.
O Ikponmwosa-Eweka, A.I. Eromosele
doaj   +1 more source

Potential deleterious effects of paracetamol dose regime used in Nigeria versus that of the United States of America

Toxicology Reports, 2022
Paracetamol, also known as acetaminophen (N-acetyl-para-aminophenol, APAP) is the world’s most used over-the-counter analgesic-antipyretic drug. Despite its good safety profile, acetaminophen can cause severe hepatotoxicity in overdose, and poisoning ...
Samuel James Offor, Cecilia Nwadiuto Amadi, Ifeyinwa Chijioke-Nwauche, Jose E. Manautou, Orish E. Orisakwe   +4 more
doaj   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Interrupted time-series analysis of regulations to reduce paracetamol (acetaminophen) poisoning.

PLoS Medicine, 2007
BackgroundParacetamol (acetaminophen) poisoning is the leading cause of acute liver failure in Great Britain and the United States. Successful interventions to reduced harm from paracetamol poisoning are needed.
Oliver W Morgan, Clare Griffiths, Azeem Majeed   +2 more
doaj   +1 more source