Results 31 to 40 of about 6,598 (209)

Inhibition and Induction by Poziotinib of Different Rat Cytochrome P450 Enzymes In Vivo and in an In Vitro Cocktail Method

open access: yesFrontiers in Pharmacology, 2021
Poziotinib is an orally active, irreversible, pan-HER tyrosine kinase inhibitor used to treat non-small cell lung cancer, breast cancer, and gastric cancer.
Jinhui Wang   +10 more
doaj   +1 more source

Metabolism of phenacetin in the rat

open access: yes, 1984
The abuse of phenacetin-containing analgesic mixtures has been linked epidemiologically with nephrotoxicity and carcinogenicity in man. In addition, clinical and histopathological tests after chronic administration of phenacetin in man and animals have ...
D'Souza, Conrad Agnello (15931457)
core   +1 more source

PHENACETIN-PoISONING [PDF]

open access: yesThe American Journal of the Medical Sciences, 1896
n ...
openaire   +2 more sources

Personal Doses of Cocaine and Coca Paste are Adulterated in Cartagena de Indias (Colombia)

open access: yesThe Scientific World Journal, 2021
Knowledge of drug composition consumed on the streets and the identification and quantification of their adulterants is essential for understanding unexpected side effects, tracking routes, and drug profiling.
Jefferson Urzola-Ortega   +2 more
doaj   +1 more source

Insights into the Adsorption Performance of Emerging Contaminants on Granular Activated Carbon

open access: yesSeparations, 2023
Emerging contaminants are being detected at a high frequency, posing significant environmental and human health challenges. This study aimed to investigate the potential of using commercial granular activated carbon for adsorbing nine aqueous emerging ...
Sang-Hoon Lee, Namgyu Kim, Donghee Park
doaj   +1 more source

The Colorimetric Determination of Phenacetin in Tablet Mixtures

open access: yes, 1960
Phenacetin may be quantitatively converted to nitrophenetidine by nitration and subsequent saponification with sodium hydroxide. The nitrophenetidine thus formed is soluble in alkaline solution and may be determined colorimetrically at 445 mμ. The method
Lee Kum-Tatt, Chan Chian-Seng
core   +1 more source

Effects of baicalin treatment on phenacetin pharmacokinetics.

open access: yes, 2014
(A) The concentration-time profiles of phenacetin (5 mg/kg,i.v.) after treatment with normal saline (control) or baicalin (450 mg/kg, i.v.) in rats. (B) The changes in concentrations(%)-time profile of phenacetin (5 mg/kg, i.v.) after treatment with ...
Hai-ling Qiao (5658073)   +6 more
core   +1 more source

Case-control study on analgesics and nephropathy (SAN): protocol

open access: yesBMC Nephrology, 2005
Background The association between intake of non-phenacetin-containing analgesics and the occurrence of chronic renal failure is still controversially discussed. A new epidemiologic study was planned and conducted in Germany and Austria.
van der Woude Fokko   +4 more
doaj   +1 more source

Pharmacokinetics of phenacetin in phenacetin abusers.

open access: yesRinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics, 1988
Although there are some reports which state that phenacetin is unlikely to be theprimary causative agent in analgesic nephropathy (Prescott, 1982), 80% of the 285phenacetin abusers observed in our clinic between 1962 and 1979 were suffering fromchronic interstitial nephritis (Nitzsche et al., 1980).
MINESHITA, Satoru   +4 more
openaire   +2 more sources

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