Results 31 to 40 of about 6,115 (211)

Personal Doses of Cocaine and Coca Paste are Adulterated in Cartagena de Indias (Colombia)

open access: yesThe Scientific World Journal, 2021
Knowledge of drug composition consumed on the streets and the identification and quantification of their adulterants is essential for understanding unexpected side effects, tracking routes, and drug profiling.
Jefferson Urzola-Ortega   +2 more
doaj   +1 more source

Insights into the Adsorption Performance of Emerging Contaminants on Granular Activated Carbon

open access: yesSeparations, 2023
Emerging contaminants are being detected at a high frequency, posing significant environmental and human health challenges. This study aimed to investigate the potential of using commercial granular activated carbon for adsorbing nine aqueous emerging ...
Sang-Hoon Lee, Namgyu Kim, Donghee Park
doaj   +1 more source

Pharmacokinetics of phenacetin in phenacetin abusers.

open access: yesRinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics, 1988
Although there are some reports which state that phenacetin is unlikely to be theprimary causative agent in analgesic nephropathy (Prescott, 1982), 80% of the 285phenacetin abusers observed in our clinic between 1962 and 1979 were suffering fromchronic interstitial nephritis (Nitzsche et al., 1980).
MINESHITA, Satoru   +4 more
openaire   +2 more sources

Metabolism of phenacetin in the rat

open access: yes, 1984
The abuse of phenacetin-containing analgesic mixtures has been linked epidemiologically with nephrotoxicity and carcinogenicity in man. In addition, clinical and histopathological tests after chronic administration of phenacetin in man and animals have ...
D'Souza, Conrad Agnello (15931457)
core   +1 more source

The Colorimetric Determination of Phenacetin in Tablet Mixtures

open access: yes, 1960
Phenacetin may be quantitatively converted to nitrophenetidine by nitration and subsequent saponification with sodium hydroxide. The nitrophenetidine thus formed is soluble in alkaline solution and may be determined colorimetrically at 445 mμ. The method
Lee Kum-Tatt, Chan Chian-Seng
core   +1 more source

Increased Phenacetin Oxidation upon the L382V Substitution in Cytochrome P450 1A2 is Associated with Altered Substrate Binding Orientation

open access: yes, 2018
Leucine382 of cytochrome P450 1A2 (CYP1A2) plays an important role in binding and O-dealkylation of phenacetin, with the L382V mutation increasing substrate oxidation (Huang and Szklarz, 2010, Drug Metab. Dispos. 38:1039–1045).
Qingbiao Huang   +2 more
core   +2 more sources

Case-control study on analgesics and nephropathy (SAN): protocol

open access: yesBMC Nephrology, 2005
Background The association between intake of non-phenacetin-containing analgesics and the occurrence of chronic renal failure is still controversially discussed. A new epidemiologic study was planned and conducted in Germany and Austria.
van der Woude Fokko   +4 more
doaj   +1 more source

Effects of baicalin treatment on phenacetin pharmacokinetics.

open access: yes, 2014
(A) The concentration-time profiles of phenacetin (5 mg/kg,i.v.) after treatment with normal saline (control) or baicalin (450 mg/kg, i.v.) in rats. (B) The changes in concentrations(%)-time profile of phenacetin (5 mg/kg, i.v.) after treatment with ...
Hai-ling Qiao (5658073)   +6 more
core   +1 more source

Preparation of Compounds Related to Phenacetin.

open access: yes, 1936
Preparation of Compounds Related to ...
(Miss) B. N. KATRAK
core   +1 more source

N-(4-Methoxy-3-nitrophenyl)acetamide

open access: yesIUCrData, 2023
The title compound, C9H10N2O4, crystallizes with a disordered nitro group in twinned crystals. Both the methoxy group and the acetamide groups are nearly coplanar with the phenyl ring, and the C—N—C—O torsion angle [0.2 (4)°] is also insignificantly ...
James E. Hines III   +4 more
doaj   +1 more source

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