Results 51 to 60 of about 6,115 (211)
Phenacetin o-deethylation by human liver microsomes: Kinetics and propranolol inhibition
, 1988 1. Phenacetin O-deethylation catalysed by human liver microcomes has been examined over a substrate concentration range of 2·5 to 700 μM using preparations of eight human liver samples.
Gillam, Elizabeth M. J. +1 more
core +1 more source
BMC Urology, 2007 Background Use of phenacetin and other analgesic and non-steroidal anti-inflammatory drugs (NSAIDs) potentially influences bladder cancer incidence, but epidemiologic evidence is limited.
Heaney John +7 more
doaj +1 more source
A case of renal pelvic tumor due to phenacetin abuse [PDF]
, 1990 An 80-year-old female had been taking phenacetin-containing analgesics due to severe pain in her legs and headache caused by SMON since 1957. The total accumulated dose of phenacetin that she had taken was about 2.3 kg.
山崎, 巌 +3 more
core
Phenacetin Isolated from , a Herbal Remedy with Antipyretic Properties
Natural Product Communications, 2009 Bursera grandifolia and other related species have been used in traditional herbal medicine in Mexico and other Latin American countries for their analgesic, antipyretic and anti-inflammatory properties.
Francisco Velázquez +4 more
doaj +1 more source
Drug Development Research, Volume 87, Issue 2, April 2026.ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu +7 more
wiley +1 more source
Food Risk Assess Europe, Volume 4, Issue 2, April 2026.Abstract Materials that come into contact with food as intended or as can be expected are also known as food contact materials or food contact articles. In addition to cardboard packaging, bakery bags and napkins, food contact materials made of paper and cardboard also include other utensils such as muffin tins and drinking straws.
German Federal Institute for Risk Assessment (BfR)
wiley +1 more source
Physiologically‐Based Pharmacokinetic Modeling of the PARP Inhibitor Niraparib
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.ABSTRACT A physiologically‐based pharmacokinetic (PBPK) model of niraparib and its primary metabolite using a relevant virtual cancer population is reported here. A series of in vitro experiments using liver S9, microsomes, and hepatocytes with various inhibitors and recombinant supersomes demonstrated that niraparib is specifically metabolized by ...
Gareth J. Lewis +3 more
wiley +1 more source
Phenacetin N-deacetylase and its non-identity with the serotonin sensitive aryl acylamidase of brain
, 1980 Phenacetin N-deacetylase was characterized in monkey brain. The enzyme needed Triton X-100 for maximal extraction and it had a high specific activity in cerebellum and in the nuclear fraction of whole monkey brain.
Oommen, Anna +2 more
core +1 more source
Journal of Chemistry, Volume 2026, Issue 1, 2026.The growing industrialization has caused the generation of highly toxic compounds such as nitroaromatic compounds. An adequate treatment to reduce the contamination of these organic compounds is necessary. The photocatalytic reduction of aromatic compounds using semiconductor materials favors the production of nitroaromatics.
Leimmy Calderon +8 more
wiley +1 more source
The gas-liquid chromatographic estimation of phenacetin and paracetamol in plasma and urine
, 1971 Methods are described for the gas-liquid chromatographic estimation of phenacetin and paracetamol in plasma and free and conjugated paracetamol in urine. p-Chloracetanilide and p-bromacetanilide were used as internal standards.
L F PRESCOTT
core +1 more source