Results 41 to 50 of about 6,598 (209)
Preparation of Compounds Related to Phenacetin.
, 1936 Preparation of Compounds Related to ...
(Miss) B. N. KATRAK
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N-(4-Methoxy-3-nitrophenyl)acetamide
IUCrData, 2023 The title compound, C9H10N2O4, crystallizes with a disordered nitro group in twinned crystals. Both the methoxy group and the acetamide groups are nearly coplanar with the phenyl ring, and the C—N—C—O torsion angle [0.2 (4)°] is also insignificantly ...
James E. Hines III +4 more
doaj +1 more source
Caffeine-phenacetin interaction in the rat: effects on absorption, metabolism and locomotor activity
, 1977 The interactive effects of caffeine and phenacetin on the locomotor activity of the DA rat involved changes in absorption and metabolism as well as effects possibly exerted at the cns level.
G A Starmer +2 more
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JSFA reports, EarlyView.Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed +5 more
wiley +1 more source
Methaemoglobinaemia: From pathophysiology to contemporary clinical management
British Journal of Haematology, EarlyView.Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley +1 more source
Drug and Alcohol Review, Volume 45, Issue 6, September 2026.ABSTRACT Introduction Drug checking is a harm reduction strategy that provides information to people who use drugs. Currently, there is a lack of standardised, replicable methods to assess drug checking technicians' use of spectroscopy‐based technologies.
Yarelix Estrada +5 more
wiley +1 more source
Evaluation of lentinan effects on cytochrome P450 activity in rats by a cocktail method [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): In this study, a cocktail of probe drugs was used to assess whether lentinan could influence the activities of rat enzymes CYP3A4, CYP2D6, CYP1A2, CYP2C19, and CYP2C9 in vivo.
Yiping Lin +8 more
doaj +1 more source
Advanced Sorbent Materials in Solid‐Phase Extraction: A Decade of Innovation and Future Perspectives
Chemistry–Methods, Volume 6, Issue 8, August 2026.This review systematically summarizes five families of advanced sorbent materials for solid‐phase extraction (SPE): nanocarbons, porous frameworks (MOFs/COFs), smart polymers, biomass‐derived sorbents, and multifunctional composites. Key molecular interactions (π–π stacking, hydrogen bonding, electrostatic attraction, host–guest recognition) are ...
Xingchen Wang +4 more
wiley +1 more source
Phenacetin o-deethylation by human liver microsomes: Kinetics and propranolol inhibition
, 1988 1. Phenacetin O-deethylation catalysed by human liver microcomes has been examined over a substrate concentration range of 2·5 to 700 μM using preparations of eight human liver samples.
Gillam, Elizabeth M. J. +1 more
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DDIapp—A Web‐Based Application for Static Drug–Drug Interaction Assessment
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.ABSTRACT In this work we describe the development of a web‐based application for static drug–drug interaction (DDI) risk assessment in accordance with the International Council for Harmonization (ICH) M12 guidance. The app was built using the Shiny for Python framework and it employs a modular mathematical modeling structure that incorporates models ...
Hirotaka Watase +5 more
wiley +1 more source