Results 71 to 80 of about 6,115 (211)
Acetanilide (ACN) and phenacetin (PNC) are compounds structurally related with acetaminophen widely used as model drugs in pharmaceutical chemistry. Based on published thermodynamic quantities for dissolution, partitioning and sublimation of ACN and PNC,
Yolima BAENA A +2 more
doaj
ABSTRACT Our aim was to investigate whether vatinoxan, a peripherally acting alpha2‐adrenoceptor antagonist, would affect the concentrations of medetomidine, midazolam, and fentanyl in the central nervous system after subcutaneous co‐administration. Twelve healthy male Wistar rats, aged between 13 and 15 weeks, were used in this study.
Juhana Honkavaara +5 more
wiley +1 more source
Plots of percentage of control in pharmacokinetic parameters of phenacetin versus AUC of baicalin.
Plots of percentage of control in pharmacokinetic parameters of phenacetin versus AUC of baicalin.
Hai-ling Qiao (5658073) +6 more
core +1 more source
Synthesis and analytical studies of phenacetin / Azlan Ahmad [PDF]
Phenacetin, an analgesic, can be synthesized in 2 ways; either Williamson Ether Synthesis or Amide Synthesis as the final process. This is due to the para substitution between ether and amide group on benzene ring. For this project, the starting material
Ahmad, Azlan
core
Paracetamol and analgesic nephropathy: Are you kidneying me?
Freya Waddington, Mark Naunton, Jackson Thomas Faculty of Health, University of Canberra, Canberra, ACT, Australia Introduction: Analgesic nephropathy is a disease resulting from the frequent use of combinations of analgesic medications over many years,
Waddington F, Naunton M, Thomas J
doaj
Based on published thermodynamic quantities for solution, partitioning and sublimation of acetanilide (ACN), acetaminophen (ACP) and Phenacetin (PNC), the thermodynamic quantities for drugs solvation in octanol-saturated water (W(ROH)) and water ...
Yolima Baena +2 more
doaj +1 more source
A thin-layer chromatography procedure is described suitable as a limit test for p-chloroacetanilide in paracetamol and phenacetin. The sample is chromatographed on silica gel together with a standard using the solvent mixture cyclohexane: acetone ...
R A Savidge, J S Wragg
core +1 more source
p53 mutations in phenacetin-associated human urothelial carcinomas
Chronic abuse of the analgesic drug phenacetin is associated with an increased risk of development of transitional cell carcinomas of the urinary tract. It is unclear whether phenacetin acts through chronic tissue damage (phenacetin nephropathy) or via a
Ohgaki, Hiroko +3 more
core
Thermodynamics of dissolution and infrared-spectroscopy of solid dispersions of phenacetin
© 2016 Journal of Advanced Pharmaceutical Technology and Research. In this work enthalpies of dissolution in water of polyethylene glycols (PEGs) having an average molecular weight of 1000 and 1400, Pluronic-F127, phenacetin as well as the composites ...
Usmanova L. +6 more
core

