Results 91 to 100 of about 11,244 (259)

Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5′-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes

Molecules, 2016
Aschantin is a bioactive neolignan found in Magnolia flos with antiplasmodial, Ca2+-antagonistic, platelet activating factor-antagonistic, and chemopreventive activities.
Soon-Sang Kwon, Ju-Hyun Kim, Hyeon-Uk Jeong, Yong Yeon Cho, Sei-Ryang Oh, Hye Suk Lee   +5 more
doaj   +1 more source

Anti-inflammatory, antinociceptive, and antipyretic effects of methanol extract of Cariniana rubra stem bark in animal models [PDF]

, 2011
Schmeda-Hirschmann, G (Schmeda-Hirschmann, Guillermo) Univ Talca, IQRN, Talca, ChileCariniana rubra Miers (Lecythidaceae), popularly known as "jequitiba-vermelho", is a large Brazilian tree whose bark is used in infusion and decoction for the treatment ...
Cechinel, V., Lima, E.F.F., Lima, J.C.S., Martins, D.T.O., Noldin, V.F., Rao, V.S.N., Santos, E.N., Schmeda-Hirschmann, G., Sousa, P.T.   +8 more
core  

Calycosin Influences the Metabolism of Five Probe Drugs in Rats

Drug Design, Development and Therapy, 2020
Mei-ling Wu, Yi-ping Lin, Yan-li Wei, Hong-jian Du, Xiao-qian Ying, Wen-zhuang Tan, Bi-e Tang Faculty of Medicine, Jinhua Polytechnic, Zhejiang, People’s Republic of ChinaCorrespondence: Bi-e TangFaculty of Medicine, Jinhua Polytechnic, No.
Wu M, Lin Y, Wei Y, Du H, Ying X, Tan W, Tang B   +6 more
doaj  

The influence of trans-resveratrol and quercetin on the activity of CYP1A2 in rat

Czech Journal of Food Sciences, 2008
Polyphenolic compounds are widely distributed in plants and are a common part of human diet. Polyphenols are known to be potent bioactive molecules, predominantly with protective effects.
Ondřej ZENDULKA, Lucia ZAHRADNÍKOVÁ, Jan JUŘICA, Jiří TOTUŠEK   +3 more
doaj   +1 more source

Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class [PDF]

, 2016
New psychoactive substances (NPS) are not tested for their cytochrome P450 (CYP) inhibition potential before consumption. Therefore, this potential was explored for tryptamine-derived NPS (TDNPS) including alpha-methyl tryptamines (AMTs), dimethyl ...
Brandt, SD, Dinger, J, Maurer, HH, Meyer, MR, Woods, C   +4 more
core   +1 more source

Influences of Oldenlandia diffusa on the CYP450 Activities in Rats Using a Cocktail Method by UHPLC-MS/MS

Biochemistry Research International, 2018
Oldenlandia diffusa has been used to treat various cancers. Cytochrome P450, a drug metabolic enzyme, might be influenced by herbal medicine. Currently, the problem that remains is the effective treatment in drug-drug interaction situation.
Yiping Lin, Yanli Wei, Xiaoxia Hu, Meilling Wu, Xiaoqian Ying, Mingxing Ding   +5 more
doaj   +1 more source

Phenacetin-induced haemolytic anaemia [PDF]

, 1971
Richard J. Davidson
openalex   +1 more source

An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes

Journal of Pharmaceutical Analysis, 2014
An efficient screening assay was developed and validated for simultaneous assessment of compound-mediated inhibition of six major human cytochrome P450 (CYP) enzymes. This method employed a cocktail of six probe substrates (i.e., phenacetin, amodiaquine,
Jing-Jing Wang, Jian-Jun Guo, Jenny Zhan, Hai-Zhi Bu, Jiunn H. Lin   +4 more
doaj   +1 more source

Pharmacokinetics of phenacetin in phenacetin abusers.

Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics, 1988
Although there are some reports which state that phenacetin is unlikely to be theprimary causative agent in analgesic nephropathy (Prescott, 1982), 80% of the 285phenacetin abusers observed in our clinic between 1962 and 1979 were suffering fromchronic interstitial nephritis (Nitzsche et al., 1980).
Satoru MINESHITA, N.R. KITTERINGHAM, T. NITZSCHE, K.D. BOCK, E.E. OHNHAUS   +4 more
openaire   +2 more sources

The Validation of Chromatographic Methods in the Detection of Cocaine and Diluents in Drugs Seized by the Civil Police in the State of Espírito Santo

Orbital: The Electronic Journal of Chemistry
Over the years, police have seized tons of cocaine in the form of cocaine hydrochloride and crack, which are often adulterated by traffickers. This work aims to use GC/MS and HPLC to determine the limit of detection (LoD) and limit of quantification ...
Karoline P. Miossi, Thays C. Valin, Ramon R. T. Bottocim, Bruno Q. Araújo, Wanderson Romão , Eustaquio V. R. de Castro, Valdemar Lacerda Jr., Alvaro Cunha Neto   +7 more
doaj   +1 more source