Results 91 to 100 of about 6,598 (209)

Calycosin Influences the Metabolism of Five Probe Drugs in Rats

Drug Design, Development and Therapy, 2020
Mei-ling Wu, Yi-ping Lin, Yan-li Wei, Hong-jian Du, Xiao-qian Ying, Wen-zhuang Tan, Bi-e Tang Faculty of Medicine, Jinhua Polytechnic, Zhejiang, People’s Republic of ChinaCorrespondence: Bi-e TangFaculty of Medicine, Jinhua Polytechnic, No.
Wu M, Lin Y, Wei Y, Du H, Ying X, Tan W, Tang B   +6 more
doaj  

The influence of trans-resveratrol and quercetin on the activity of CYP1A2 in rat

Czech Journal of Food Sciences, 2008
Polyphenolic compounds are widely distributed in plants and are a common part of human diet. Polyphenols are known to be potent bioactive molecules, predominantly with protective effects.
Ondřej ZENDULKA, Lucia ZAHRADNÍKOVÁ, Jan JUŘICA, Jiří TOTUŠEK   +3 more
doaj   +1 more source

Gas chromatographic analysis of acetylsalicylic acid, phenacetin, caffeine, and codeine in APC and codeine tablets

, 1969
All active ingredients in APC and codeine tablets are determined by gas chromatographic procedures after separation of acetylsalicylic and phenacetin from caffeine and codeine.
L H Booth, M J Caughey, Earl B Dechene
core   +1 more source

Influences of Oldenlandia diffusa on the CYP450 Activities in Rats Using a Cocktail Method by UHPLC-MS/MS

Biochemistry Research International, 2018
Oldenlandia diffusa has been used to treat various cancers. Cytochrome P450, a drug metabolic enzyme, might be influenced by herbal medicine. Currently, the problem that remains is the effective treatment in drug-drug interaction situation.
Yiping Lin, Yanli Wei, Xiaoxia Hu, Meilling Wu, Xiaoqian Ying, Mingxing Ding   +5 more
doaj   +1 more source

Differential inhibition of human liver phenacetin o-deethylation by histamine and four histamine h2-receptor antagonists

, 1988
1. The effects of histamine and four histamine H-2 receptor antagonists on phenacetin O-deethylation by microsomal preparations of four human livers were quantified by a radiometric-thin layer chromatographic method. 2. Histamine and three of these drugs,
Reilly, P. E B, Gillam, E. M J, Mason, S. R.   +2 more
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Omeprazole Does Not Enhance the Metabolism of Phenacetin, a Marker of CYP1A2 Activity, in Healthy Volunteers

, 1994
Omeprazole has been reported to increase cytochrome P450IA2 (CYP1A2) activity in vitro, but whether this effect also occurs in vivo is controversial. To clarify this issue, the effect of omeprazole (20 mg/day for 8 days) on the kinetics and metabolism of
S. Xiaodong, PERUCCA, EMILIO, GATTI, GIULIANA, CREMA, FRANCESCA, CIPOLLA, GIOVANNA, A. Bartoli   +5 more
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Demonstrating the Influence of Solvent Choice and Crystallization Conditions on Phenacetin Crystal Habit and Particle Size Distribution

, 2015
Phenacetin was used as a model pharmaceutical compound to investigate the impact of solvent choice and crystallization conditions on the crystal habit and size distribution of the final crystallized product.
Croker, D. M., Lawrence, S. E., Horgan, D. E., Moynihan, H. A., Kelly, D. M., Rasmuson, Åke Christoffer,, Hodnett, B. K.   +6 more
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Effect of malaria infection and endotoxin-induced fever on phenacetin o-deethylation by rat liver microsomes

, 1993
We have investigated the effect of malaria infection with the rodent parasite Plasmodium berghei and fever induced by Escherichia colt endotoxin on the metabolism of phenacetin to paracetamol by rat liver microsomes from young (4 weeks old) male Wistar ...
Glazier, Anthony P., Ward, Steve, Edwards, Geoffrey, Kokwaro, Gilbert O., Breckenridge, Alasdair M.   +4 more
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The Validation of Chromatographic Methods in the Detection of Cocaine and Diluents in Drugs Seized by the Civil Police in the State of Espírito Santo

Orbital: The Electronic Journal of Chemistry
Over the years, police have seized tons of cocaine in the form of cocaine hydrochloride and crack, which are often adulterated by traffickers. This work aims to use GC/MS and HPLC to determine the limit of detection (LoD) and limit of quantification ...
Karoline P. Miossi, Thays C. Valin, Ramon R. T. Bottocim, Bruno Q. Araújo, Wanderson Romão , Eustaquio V. R. de Castro, Valdemar Lacerda Jr., Alvaro Cunha Neto   +7 more
doaj   +1 more source

A case of renal pelvic tumor due to phenacetin abuse [PDF]

, 2002
65歳女.慢性頭痛のためセデス末(フェナセチン含有量400mg/包)を内服していたが, その後, 市販薬のセデスA錠(フェナセチン含有せず)に内服変更していた.又, 近医の処方によりサリイタミン(フェナセチン含有量250mg/包)2包/日を内服していた.通算のフェナセチン総摂取量は約8kgであった.無症候性肉眼的血尿で受診した.DIPにより左腎盂腫瘍と診断した.左腎盂尿管全摘出術を施行した.術後経過は良好で退院し, 経過観察中である.組織学的所見は移行上皮癌grade 2で ...
小島, 圭太郎, 堀, 武, 前田, 真一, 西野, 好則, 玉木, 正義, 出口, 隆   +5 more
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